| 1. |
- Danesh, John, et al.
(författare)
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Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis
- 2005
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Ingår i: JAMA: The Journal of the American Medical Association. - : American Medical Association (AMA). - 1538-3598 .- 0098-7484. ; 294:14, s. 1799-1809
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Forskningsöversikt (refereegranskat)abstract
- CONTEXT: Plasma fibrinogen levels may be associated with the risk of coronary heart disease (CHD) and stroke. OBJECTIVE: To assess the relationships of fibrinogen levels with risk of major vascular and with risk of nonvascular outcomes based on individual participant data. DATA SOURCES: Relevant studies were identified by computer-assisted searches, hand searches of reference lists, and personal communication with relevant investigators. STUDY SELECTION: All identified prospective studies were included with information available on baseline fibrinogen levels and details of subsequent major vascular morbidity and/or cause-specific mortality during at least 1 year of follow-up. Studies were excluded if they recruited participants on the basis of having had a previous history of cardiovascular disease; participants with known preexisting CHD or stroke were excluded. DATA EXTRACTION: Individual records were provided on each of 154,211 participants in 31 prospective studies. During 1.38 million person-years of follow-up, there were 6944 first nonfatal myocardial infarctions or stroke events and 13,210 deaths. Cause-specific mortality was generally available. Analyses involved proportional hazards modeling with adjustment for confounding by known cardiovascular risk factors and for regression dilution bias. DATA SYNTHESIS: Within each age group considered (40-59, 60-69, and > or =70 years), there was an approximately log-linear association with usual fibrinogen level for the risk of any CHD, any stroke, other vascular (eg, non-CHD, nonstroke) mortality, and nonvascular mortality. There was no evidence of a threshold within the range of usual fibrinogen level studied at any age. The age- and sex- adjusted hazard ratio per 1-g/L increase in usual fibrinogen level for CHD was 2.42 (95% confidence interval [CI], 2.24-2.60); stroke, 2.06 (95% CI, 1.83-2.33); other vascular mortality, 2.76 (95% CI, 2.28-3.35); and nonvascular mortality, 2.03 (95% CI, 1.90-2.18). The hazard ratios for CHD and stroke were reduced to about 1.8 after further adjustment for measured values of several established vascular risk factors. In a subset of 7011 participants with available C-reactive protein values, the findings for CHD were essentially unchanged following additional adjustment for C-reactive protein. The associations of fibrinogen level with CHD or stroke did not differ substantially according to sex, smoking, blood pressure, blood lipid levels, or several features of study design. CONCLUSIONS: In this large individual participant meta-analysis, moderately strong associations were found between usual plasma fibrinogen level and the risks of CHD, stroke, other vascular mortality, and nonvascular mortality in a wide range of circumstances in healthy middle-aged adults. Assessment of any causal relevance of elevated fibrinogen levels to disease requires additional research.
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| 2. |
- Gupta, M P, et al.
(författare)
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Medical ethnobotany of the Teribes of Bocas del Toro, Panama
- 2005
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Ingår i: Journal of Ethnopharmacology. - : Elsevier BV. - 0378-8741 .- 1872-7573. ; 96:3, s. 389-401
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Tidskriftsartikel (refereegranskat)abstract
- Ethnomedical uses of 108 medicinal plant species, belonging to 52 families, 89 genera, used by the Teribe Amerindians of Bocas del Toro Province in Panama. along with their socio-cultural practices are reported here. The methods of administration of the herbal remedies, the plant parts used, their families and local names are also documented. The recorded medicinal plants were used mainly for fever, various type of pain and inflammation. The potential value of 26 plants and their traditional uses was elucidated through literature search.
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| 3. |
- Volski, V., et al.
(författare)
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Overview of the software integration activities within ACE
- 2006
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Ingår i: First European Conference on Antennas and Propagation (EuCAP), 2006, Nice, France, 6 - 10 November 2006. - : IEEE. - 0379-6566. - 9789290929376 ; 626 SP
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Konferensbidrag (refereegranskat)abstract
- The ACE project initiated the start of several integration activities between European institutions involved in electromagnetic modeling of antennas with planar or conformal topologies. The goal of the integration activities was / is not to create a global software package that integrates the software of all partners, but to initiate a long term process for antenna software integration activities within the European antenna community. During the first two years of ACE the integration activities were performed in several groups with a rather small number of partners in each group. The groups were formed by partners who wanted to integrate a specific approach developed by one partner into the software code of another partner. This allows increasing the capability and efficiency of a software code. In this paper a short overview of all integration activities is given.
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| 4. |
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| 5. |
- Espinosa, E. H., et al.
(författare)
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Highly Selective NO2 Gas Sensors made of MWCNTs and WO3 Hybrid Layers
- 2007
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Ingår i: Journal of the Electrochemical Society. - : The Electrochemical Society. - 0013-4651 .- 1945-7111. ; 154:5, s. J141-J149
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Tidskriftsartikel (refereegranskat)abstract
- Hybrid gas sensors were fabricated by means of multiwalled carbon nanotubes (MWCNTs) covered by W O3 deposited by an advanced reactive gas deposition method. In order to increase the dispersion of nanotubes and attach functional groups to their surface so as to enhance their compatibility with other compounds, the MWCNTs were functionalized in two different radio-frequency plasmas (oxygen or hydrogen) under different operating conditions. X-ray photoelectron spectroscopy, scanning electron microscopy, and atomic force microscopy were employed to analyze the composition and morphology of the hybrid films. Gas sensors based on such films were found to be very selective to N O2 when operated at room temperature. No cross-sensitivity was found to other hazardous gases such as N H3 or CO.
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