| 1. |
|
|
| 2. |
|
|
| 3. |
|
|
| 4. |
- Evangeli, M, et al.
(författare)
-
ERRATUM
- 2009
-
Ingår i: AIDS care. - : Informa UK Limited. - 1360-0451 .- 0954-0121. ; 21:4, s. 539-539
-
Tidskriftsartikel (refereegranskat)
|
|
| 5. |
|
|
| 6. |
- Analitis, A, et al.
(författare)
-
Effects of cold weather on mortality : results from 15 European cities within the PHEWE project.
- 2008
-
Ingår i: American journal of epidemiology. - : Oxford University Press (OUP). - 1476-6256 .- 0002-9262. ; 168:12, s. 1397-408
-
Tidskriftsartikel (refereegranskat)abstract
- Weather-related health effects have attracted renewed interest because of the observed and predicted climate change. The authors studied the short-term effects of cold weather on mortality in 15 European cities. The effects of minimum apparent temperature on cause- and age-specific daily mortality were assessed for the cold season (October-March) by using data from 1990-2000. For city-specific analysis, the authors used Poisson regression and distributed lag models, controlling for potential confounders. Meta-regression models summarized the results and explored heterogeneity. A 1 degrees C decrease in temperature was associated with a 1.35% (95% confidence interval (CI): 1.16, 1.53) increase in the daily number of total natural deaths and a 1.72% (95% CI: 1.44, 2.01), 3.30% (95% CI: 2.61, 3.99), and 1.25% (95% CI: 0.77, 1.73) increase in cardiovascular, respiratory, and cerebrovascular deaths, respectively. The increase was greater for the older age groups. The cold effect was found to be greater in warmer (southern) cities and persisted up to 23 days, with no evidence of mortality displacement. Cold-related mortality is an important public health problem across Europe. It should not be underestimated by public health authorities because of the recent focus on heat-wave episodes.
|
|
| 7. |
- Bergemalm, Daniel, 1977-, et al.
(författare)
-
Changes in the spinal cord proteome of an amyotrophic lateral sclerosis murine model determined by differential in-gel electrophoresis
- 2009
-
Ingår i: Molecular and cellular proteomics. - : The American Society for Biochemistry and Molecular Biology,Inc. - 1535-9484. ; 8:6, s. 1306-1317
-
Tidskriftsartikel (refereegranskat)abstract
- Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by loss of motor neurons resulting in progressive paralysis. To date, more than 140 different mutations in the gene encoding CuZn-superoxide dismutase (SOD1) have been associated with ALS. Several transgenic murine models exist in which various mutant SOD1s are expressed. We have used differential in-gel electrophoresis (DIGE) to analyze the changes in the spinal cord proteome induced by expression of the unstable SOD1 truncation mutant G127insTGGG (G127X) in mice. Unlike mutants used in most other models, G127X lacks SOD activity and is present at low levels, thus reducing the risk of overexpression artifacts. The mice were analyzed at their peak body weights, just before onset of symptoms. Variable importance plot (VIP) analysis showed that 420 of 1,800 detected protein spots contributed significantly to the differences between the groups. By MALDI-TOF MS analysis, 54 proteins were identified. One spot was found to be a covalently linked mutant SOD1 dimer, apparently analogous to SOD1 immunoreactive bands migrating at double the molecular weight of SOD1 monomers previously detected in humans and mice carrying mutant SOD1s and in sporadic ALS cases. Analyses of affected functional pathways, and the subcellular representation of alterations suggest that the toxicity exerted by mutant SODs induces oxidative stress and affects mitochondria, cellular assembly/organization, and protein degradation.
|
|
| 8. |
- Duda, L.-C., et al.
(författare)
-
Resonant inelastic X-ray scattering at the NiO O K-resonance: non-local charge-transfer and double singlet excitations
- 2007
-
Ingår i: MAX-lab. - Lund : MAX-lab. ; , s. 270-271
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- NiO is one of the prototypical compounds that has highlighted the importance of correlation effects in transition metal oxides. Core level spectroscopies bear evidence for the highly correlated nature of low energy excitations. For instance, the asymmetry of the Ni2p-line shape has been attributed to non-local charge transfer excitations and multi-site cluster calculations show that solidstate effects generally are appreciable for correlated materials, such as cuprates and high Tc-compounds.....
|
|
| 9. |
|
|
| 10. |
|
|
