| 1. |
- Fransson, Thord, et al.
(författare)
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Svensk ringmärkning 2013
- 2014
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Ingår i: SOF 2014. Fågelåret 2013. - Halmstad : Swedish Ornithological Society. ; , s. 23-30
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 2. |
- Magnusson, Lina, et al.
(författare)
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Malawian prosthetic and orthotic users' mobility and satisfaction with their lower limb assistive device
- 2013
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Ingår i: Journal of Rehabilitation Medicine. - : Medical Journals Sweden AB. - 1650-1977 .- 1651-2081. ; 45:4, s. 385-391
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To investigate patients’ mobility and satisfaction with their lower limb prosthetic or orthotic device and related service delivery in Malawi and to compare groups of patients regarding type and level of device and demographics.METHODS: Questionnaires were used to collect self-report data from 83 patients.RESULTS: Ninety percent of prostheses or orthoses were in use by patients, but approximately half of these needed repair. Thirty-nine percent reported pain when using their assistive device. The majority of patients were able to rise from a chair (77%), move around the home (80%), walk on uneven ground (59%) and travel by bus or car (56%). However, patients had difficulties walking up and down hills (78%) and stairs (60%). In general, patients were quite satisfied with their assistive device (mean of 3.9 out of 5) and very satisfied with the service provided (mean of 4.4 out of 5). Access to repairs and servicing were rated as most important, followed by durability and follow-up services. Lack of finances to pay for transport was a barrier to accessing the prosthetic and orthotic centre.CONCLUSION: Patients were satisfied with the assistive device and service received, despite reporting pain associated with use of the device and difficulties ambulating on challenging surfaces.
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| 3. |
- Magnusson, Lina, et al.
(författare)
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Malawian Prosthetic And Orthotic Users’ Performance And Satisfaction With Their Lower Limb Assistive Device
- 2013
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Konferensbidrag (refereegranskat)abstract
- Introduction: This study aimed to investigate patients’ performance and satisfaction with their lower limb prosthetic or orthotic device and their satisfaction with prosthetic and orthotic service delivery in Malawi.Method: Eighty-three patients participated in the study. Questionnaires were used to collect self- reported data.Result: Ninety per cent of prosthetic and orthotic devices were in use. Patients were quite satisfied with their device (mean score of 3.9 out of 5) and very satisfied with the service provided (mean score of 4.4 out of 5). The majority of patients were able to move around the home (80%), rise from a chair (77%), walk on uneven ground (59%) and travel by bus or car (56%). Patients had difficulties or could not walk at all on; stairs (60%) and hills (79%),Thirty-nine percent reported pain when using the assistive device. Forty-eight percent of the devices were in use but needed repairs and 10 % were never used or completely broken. Access to repairs and servicing were rated by patients as most important, followed by durability of the device and follow up services. Lack of finances to pay for transport was a common barrier to accessing the prosthetic and orthotic centre.Discussion: Prosthetic and orthotic devices can be further improved in order to accommodate for ambulation on uneven surfaces, hills and stairs, as well as increasing patients’ ability to walk long distances with reduced pain.Conclusion:Patients were satisfied with the device and service received and the majority of prosthetic and orthotic patients in this study reported increased mobility when using their assistive devices. However, patients reported pain associated with use of the device and difficulties were experienced when walking in hills and on stairs. Costs associated with transport to the prosthetic and orthotic facility prevented them from receiving follow-up and repair services
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| 4. |
- Magnusson, Lina, et al.
(författare)
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Mobility and satisfaction with lower-limb prostheses and orthoses among users in Sierra Leone: A cross-sectional study
- 2014
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Ingår i: Journal of Rehabilitation Medicine. - : Medical Journals Sweden AB. - 1651-2081 .- 1650-1977. ; 46:5, s. 438-446
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: To investigate patients' mobility and satisfaction with their lower-limb prosthetic or orthotic device and related service delivery in Sierra Leone; to compare groups of patients regarding type and level of assistive device, gender, area of residence, income; and to identify factors associated with satisfaction with the assistive device and service. Methods: A total of 139 patients answered questionnaires, including the Quebec User Evaluation of Satisfaction with Assistive Technology questionnaire (QUEST 2.0). Results: Eighty-six percent of assistive devices were in use, but half needed repair. Thirty-three percent of patients reported pain when using their assistive device. Patients had difficulties or could not walk at all on: uneven ground (65%); hills (75%); and stairs (66%). Patients were quite satisfied with their assistive device and the service (mean 3.7 out of 5 in QUEST), but reported 886 problems. Approximately half of the patients could not access services. In relation to mobility and service delivery, women, orthotic patients and patients using above-knee assistive devices had the poorest results. The general condition of the assistive device and patients' ability to walk on uneven ground were associated with satisfaction with the assistive devices and service. Conclusion: Patients reported high levels of mobility while using their device although they experienced pain and difficulties walking on challenging surfaces. Limitations in the effectiveness of assistive devices and limited access to follow-up services and repairs were issues desired to be addressed.
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| 5. |
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| 6. |
- Peyrard-Janvid, Myriam, et al.
(författare)
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Dominant Mutations in GRHL3 Cause Van der Woude Syndrome and Disrupt Oral Periderm Development
- 2014
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Ingår i: American Journal of Human Genetics. - : Elsevier BV. - 0002-9297 .- 1537-6605. ; 94:1, s. 23-32
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Tidskriftsartikel (refereegranskat)abstract
- Mutations in interferon regulatory factor 6 (IRF6) account for similar to 70% of cases of Van der Woude syndrome (VWS), the most common syndromic form of cleft lip and palate. In 8 of 45 VWS-affected families lacking a mutation in IRF6, we found coding mutations in grainyhead-like 3 (GRHL3). According to a zebrafish-based assay, the disease-associated GRHL3 mutations abrogated periderm development and were consistent with a dominant-negative effect, in contrast to haploinsufficiency seen in most VWS cases caused by IRF6 mutations. In mouse, all embryos lacking Grhl3 exhibited abnormal oral periderm and 17% developed a cleft palate. Analysis of the oral phenotype of double heterozygote (Irf6(+/-);Grhl3(+/-)) murine embryos failed to detect epistasis between the two genes, suggesting that they function in separate but convergent pathways during palatogenesis. Taken together, our data demonstrated that mutations in two genes, IRF6 and GRHL3, can lead to nearly identical phenotypes of orofacial cleft. They supported the hypotheses that both genes are essential for the presence of a functional oral periderm and that failure of this process contributes to VWS.
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