| 1. |
- Roland, P, et al.
(author)
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A database generator for human brain imaging
- 2001
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In: TINS - Trends in Neurosciences. - 0166-2236 .- 1878-108X. ; 24:10, s. 562-564
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Journal article (peer-reviewed)abstract
- Sharing scientific data containing complex information requires new concepts and new technology. NEUROGENERATOR is a database generator for the neuroimaging community. A database generator is a database that generates new databases. The scientists submit raw PET and fMRI data to NEUROGENERATOR, which then processes the data in a uniform way to create databases of homogenous data suitable for data sharing, met-analysis and modelling the human brain at the systems level. These databases are then distributed to the scientists.
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| 2. |
- Fredriksson, A., et al.
(author)
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Labeling of human C-peptide by conjugation with N-succinimidyl-4- F-18 fluorobenzoate
- 2001
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In: Journal of labelled compounds & radiopharmaceuticals. - : Wiley. - 0362-4803 .- 1099-1344. ; 44:7, s. 509-519
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Journal article (peer-reviewed)abstract
- We have labeled proinsulin connecting peptide (C-peptide) with fluorine-18 (t(1/2) = 109.7min) in order to perform in vivo biodistribution and pharmacokinetic studies with position emission tomography (PET). This study reports the optimization of the conjugation labeling in the N-terminal with N-succinimidyl-4-[F-18]fluorobenzoate ([F-18]SFB). In preparative runs N-4-[F-18]fluorobenzoyl-C-peptide ([F-18]FB-C-peptide) was produced in 8-12% decay-corrected yields, counted from resolubilized [F-18]F-, in less than 5h. The specific radioactivity of [F-18]FB-C-peptide, determined using ELISA for one of the preparations, was around 70 GBq/mu mol at end of synthesis.
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| 5. |
- Mahmoudi, J., et al.
(author)
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An experimental and numerical study on the modelling of fluid flow, heat transfer and solidification in a copper continuous strip casting process
- 2003
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In: Materials transactions. - : Japan Institute of Metals. - 1345-9678 .- 1347-5320. ; 44:9, s. 1741-1751
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Journal article (peer-reviewed)abstract
- An experimental and numerical study was carried out to investigate the solidification process in a copper continuous strip casting process. Heat flow and solidification process has been experimentally studied. Cooling curves during solidification were registered using a thermocouple of type K connected to a data acquisition system. Temperature measurements in the mould and cooling water were also performed. The numerical model considers a generalized set of mass, momentum and heat equations that is valid for the solid, liquid and solidification interval in the cast. A k - epsilon turbulence model, produced with the commercial program CFX, is used to analyse the solidification process of pure copper in the mould region of the caster. The fluid flow, temperature and heat flux distributions in the mould region of the caster were computed. The shape and location of the solidification front were also determined. The effects of the parameters such as heat transfer coefficient, casting speed, casting temperature. heat of fusion and specific heat on the shape and location of the solidification front and the heat transport at the mould-cast interface were investigated. The predicted temperature and heat flux distributions were compared with experimental measurements, and reasonable agreement was obtained.
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| 7. |
- Tinoco, J., et al.
(author)
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Thermal analysis of nodular and lamellar eutectic cast iron under different cooling rates
- 2003
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In: International Journal of Cast Metals Research. - : Informa UK Limited. - 1364-0461 .- 1743-1336. ; 16:03-jan, s. 53-58
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Journal article (peer-reviewed)abstract
- Thermal analysis was performed on neareutectic nodular and lamellar cast iron,alloys under different cooling rates. In a DTA setup, cooling rates from 0.08 K/sec to 0.35 K/sec were used, while in a mirror furnace setup cooling rates up to 55 K/sec were reached. At low cooling rates, the solidification behaviour was analyzed by interrupting the process through quenching. The volume fraction of each phase and substructure was evaluated together with the latent heat at different solidification times. It was observed that the growth rate of the nodules decreases with time. Measurements on the number of nodules indicate that the nucleation rate is constant through the solidification process. The measured latent heat of fusion varies along the solidification process for nodular cast iron but not for lamellar cast iron. This difference in the solidification behaviour may be explained by different diffusion kinetic laws. It was also found that the measured latent heat of fusion decreases when the cooling rate increases. Alloys with nodular graphite showed lower latent heat in comparison with the alloys with lamellar graphite at high cooling rates. This effect is explained by means of thermodynamics of lattice defects, such as vacancies, formed in the austenite and graphite phase during solidification.
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