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Träfflista för sökning "WFRF:(Friberg Emilie) srt2:(2010-2014)"

Sökning: WFRF:(Friberg Emilie) > (2010-2014)

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1.
  • Friberg, Emilie, et al. (författare)
  • Sucrose, High-Sugar Foods, and Risk of Endometrial Cancer-a Population-Based Cohort Study
  • 2011
  • Ingår i: Cancer Epidemiology, Biomarkers and Prevention. - : AMER ASSOC CANCER RESEARCH. - 1055-9965 .- 1538-7755. ; 20:9, s. 1831-1837
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Consumption of high-sugar foods stimulates insulin production, which has been associated with endometrial cancer. Although a relationship between sucrose, high-sugar food consumption, and endometrial cancer risk is biologically plausible, this hypothesis has previously been explored in very few studies. Methods: We used data from the Swedish Mammography Cohort, including 61,226 women aged 40 to 74 years. We examined the association between consumption of total sucrose, high-sugar foods (at baseline 1987-1990 and 1997) and endometrial cancer risk by using Cox proportional hazards models to estimate incidence rate ratios (RR) with 95% CI. Results: During 18.4 years of follow-up, 729 participants were diagnosed with incident endometrial cancer. Total sucrose intake and consumption of sweet buns and cookies was associated with increased risk of endometrial cancer. RRs (with 95% CIs) for consuming more than 35 grams of sucrose per day and consuming sweet buns and cookies more than 3 times per week were 1.36 (1.04-1.77) and 1.42 (1.15-1.75) as compared with less than 15 grams of sucrose per day and consuming sweet buns and cookies less than 0.5 times per week, respectively. RRs for consuming more than 15 grams of sucrose per day as compared with 15 grams or less were 1.97 (1.27-3.04) among obese women and 1.56 (1.20-2.04) among women with low fat intake. Conclusions: These data indicate that sucrose intake and consumption of sweet buns and cookies may be associated with increased risk of endometrial cancer. Impact: Given the high intake of sweetened foods, these results have public health implications in terms of prevention of endometrial cancer. Cancer Epidemiol Biomarkers Prev; 20(9); 1831-7. (C)2011 AACR.
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2.
  • Genkinger, Jeanine M., et al. (författare)
  • Long-term dietary heme iron and red meat intake in relation to endometrial cancer risk
  • 2012
  • Ingår i: American Journal of Clinical Nutrition. - : OXFORD UNIV PRESS. - 0002-9165 .- 1938-3207. ; 96:4, s. 848-854
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Heme and total iron, present in meat, have been hypothesized to promote carcinogenesis. Few prospective studies have examined the associations between intakes of heme and total iron, types of meat, and endometrial cancer risk. Objective: We evaluated the associations between intakes of heme and total iron, types of meat, and risk of endometrial cancer in a large cohort of women. Design: Among 60,895 women in the Swedish Mammography Cohort, 720 endometrial cancer cases were confirmed during 21 y of follow-up. RRs and 95% CIs were calculated by Cox proportional hazards models. Results: A comparison of the highest with the lowest quartile showed a 20-30% higher risk of endometrial cancer for higher intakes of heme iron (RR: 1.24; 95% CI: 1.01, 1.53 for >= 1.63 compared with <0.69 mg/d), total iron (RR: 1.31; 95% CI: 1.07, 1.61 for >= 15.09 compared with <12.27 mg/d), and liver (RR: 1.29; 95% CI: 1.06, 1.56 for >= 100 compared with <100 g/wk). No statistically significant associations were observed between intakes of red and processed meats and endometrial cancer risk. RRs did not greatly differ when we stratified by BMI, parity, and intakes of alcohol, vitamin C, or zinc or when we excluded patients with diabetes. Conclusions: Our study suggests a modest positive association between heme iron, total iron, and liver intakes and endometrial cancer risk; no statistically significant associations were observed for intakes of other red and processed meats and endometrial cancer risk. The Swedish Mammography Cohort was registered at clinicaltrials.gov as NCT01127698. Am J Clin Nutr 2012;96:848-54.
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3.
  • Wawrzyniak, Agata, et al. (författare)
  • Dietary, anthropometric, and lifestyle correlates of serum carotenoids in postmenopausal women
  • 2013
  • Ingår i: European Journal of Nutrition. - : SPRINGER HEIDELBERG. - 1436-6207 .- 1436-6215. ; 52:8, s. 1919-1926
  • Tidskriftsartikel (refereegranskat)abstract
    • Concentration of carotenoids in the serum is a biomarker of mainly vegetable and fruit consumption. However, the levels of carotenoids in humans may decline with age and can also depend on body fat, alcohol consumption, and cigarette smoking. Food intake and characteristics of 159 randomly chosen women aged 56-75 years were obtained by a self-administered questionnaire. Serum concentrations of carotenoids were determined by high-performance liquid chromatography. Estimation of fat mass was carried out by dual energy X-ray absorptiometry. The estimated total daily intake of carotenoids was 9.75 mg: alpha-carotene 10.6 %; beta-carotene 35.6 %; lutein/zeaxanthin 27.1 %; beta-cryptoxanthin 4.7 %; and lycopene 22.0 %. We observed statistically significant positive correlations between concentrations of serum carotenoids and their estimated intakes (r = 0.11 lycopene to 0.38 beta-carotene) and fruit and vegetable intake (r = 0.15 lycopene to 0.30 beta-carotene). Concentration of serum carotenoids positively correlated with education (r = 0.17 alpha-carotene to 0.29 lycopene) and alcohol intake (r = 0.02 alpha-carotene to r = 0.25 lycopene). Inverse correlations were with the age (r = -0.18 alpha-carotene to -0.42 lycopene) and fat mass (r = -0.15 lycopene to -0.29 alpha-, beta-carotene). In this population of healthy postmenopausal women, serum concentrations of carotenoids declined with increasing age and body fat mass. The concentrations were increased among women with high vegetable and fruit consumption, moderate alcohol intake, and high level of education.
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