| 1. |
- Gagliardi, F. M., et al.
(författare)
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Intra-cavitary dosimetry for IMRT head and neck treatment using thermoluminescent dosimeters in a naso-oesophageal tube
- 2009
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Ingår i: Physics in Medicine and Biology. - : IOP Publishing. - 1361-6560 .- 0031-9155. ; 54:12, s. 3649-3657
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Tidskriftsartikel (refereegranskat)abstract
- Complex intensity-modulated radiation therapy (IMRT) treatment plans require rigorous quality assurance tests. The aim of this study was to independently verify the delivered dose inside the patient in the region of the treatment site. A flexible naso-gastric tube containing thermoluminescent dosimeters (TLDs) was inserted into the oesophagus via the sinus cavity before the patient's first treatment. Lead markers were also inserted into the tube in order that the TLD positions could be accurately determined from the lateral and anterior posterior electronic portal images taken prior to treatment. The measured dose was corrected for both daily linac output variations and the estimated dose received from the portal images. The predicted dose for each TLD was determined from the treatment planning system and compared to the measured TLD doses. The results comprise 431 TLD measurements on 43 patients. The mean measured-to-predicted dose ratio was 0.988 +/- 0.011 (95% confidence interval) for measured doses above 0.2 Gy. There was a variation in this ratio when the measurements were separated into low dose (0.2-1.0 Gy), medium dose (1.0-1.8 Gy) and high dose (> 1.8 Gy) measurements. The TLD-loaded, naso-oesophageal tube for in vivo dose verification is straightforward to implement, and well tolerated by patients. It provides independent reassurance of the delivered dose for head and neck IMRT.
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| 2. |
- Gagliardi, F, et al.
(författare)
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The EU datagrid project : Building and Operating a large scale Grid Infrastructure
- 2006
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Ingår i: Engineering the Grid. - : American Scientific Publishers. - 1588830381
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Bokkapitel (refereegranskat)abstract
- The EU DataGrid project (EDG) has its aim to develop a large-scale research testbed for Grid computing. During the lifetime of the Project (January 2001 - March 2004) high level Grid middleware has been developed and a large scale testbed has been up and running continuously since the beginning of 2002. Three application domains are using this testbed to explore the potential Grid computing has for their production environments: Particle Physics, Earth Observation and Biomedics. The EDG testbed, spanning some 20 major sites all over Europe as well as sites in the US and Asia is one of the largest Grid infrastructures in the world. The software developed by EDG is being exploited in many national and international Grid projects, most notably the LCG production infrastructure. In this talk we give a brief overview on Grid computing, present the architecture of the EDG middleware, report on our experiences in deploying and operating a large scale Grid infrastructure and discuss how our application groups are using this infrastructure. An outlook on the future perspectives of Grid computing is concluding the talk.
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