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The use of Faecal M...
The use of Faecal Microbiota Transplantation (FMT) in Europe : A Europe-wide survey
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- Baunwall, Simon Mark Dahl (författare)
- Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark,Aarhus Univ Hosp, Denmark
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- Terveer, Elisabeth M. (författare)
- Department of Medical Microbiology, Leiden University Medical Center, Leiden, the Netherlands; Netherlands Donor Feces Bank, Leiden University Medical Center, Leiden, the Netherlands,Leiden Univ Med Ctr, Netherlands; Leiden Univ Med Ctr, Netherlands
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- Dahlerup, Jens Frederik (författare)
- Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark,Aarhus Univ Hosp, Denmark
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- Erikstrup, Christian (författare)
- Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark,Aarhus Univ Hosp, Denmark
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- Arkkila, Perttu (författare)
- Department of Gastroenterology, Helsinki University Hospital and Helsinki University, Helsinki, Finland,Helsinki Univ Hosp, Finland; Univ Helsinki, Finland
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- Vehreschild, Maria Jgt (författare)
- Department of Internal Medicine II, Infectious Diseases, University Hospital Frankfurt, Frankfurt am Main, Germany; ESCMID Study Group for Host and Microbiota Interaction (ESGHAMI), Basel, Switzerland; Department I of Internal Medicine, University of Cologne, Cologne, Germany; German Centre for Infection Research (DZIF), Partner site Bonn-Cologne, Germany,Univ Hosp Frankfurt, Germany; ESCMID Study Grp Host & Microbiota Interact ESGHA, Switzerland; Univ Cologne, Germany; German Ctr Infect Res DZIF, Germany
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- Ianiro, Gianluca (författare)
- Digestive Disease Center, CEMAD, Fondazione Policlinico Universitario Gemelli IRCCS, Rome, Italy,Fdn Policlin Univ Gemelli IRCCS, Italy
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- Gasbarrini, Antonio (författare)
- Digestive Disease Center, CEMAD, Fondazione Policlinico Universitario Gemelli IRCCS, Rome, Italy,Fdn Policlin Univ Gemelli IRCCS, Italy
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- Sokol, Harry (författare)
- Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, CRSA, AP-HP, Saint Antoine Hospital, Gastroenterology Department, Paris, France; INRA, UMR1319 Micalis, AgroParisTech, Jouy-en-Josas, France; French Group of Faecal Microbiota Transplantation (GFTF), Paris, France,Sorbonne Univ, France; AgroParisTech, France; French Grp Faecal Microbiota Transplantat GFTF, France
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- Kump, Patrizia K. (författare)
- Division of Gastroenterology and Hepatology, Medical University of Graz, Graz, Austria,Med Univ Graz, Austria
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- Satokari, Reetta (författare)
- Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland,Univ Helsinki, Finland
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- De Looze, Danny (författare)
- Department of Gastroenterology, Ghent University Hospital, Ghent, Belgium,Ghent Univ Hosp, Belgium
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- Vermeire, Séverine (författare)
- Department Gastroenterology and Hepatology, KU Leuven University Hospitals Leuven & KU Leuven, Belgium,Katholieke Univ Leuven, Belgium; Katholieke Univ Leuven, Belgium
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- Nakov, Radislav (författare)
- Clinic of Gastroenterology, Tsaritsa Yoanna University Hospital, Sofia, Bulgaria,Tsaritsa Yoanna Univ Hosp, Bulgaria
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- Brezina, Jan (författare)
- Hepatogastroenterology Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic,Inst Clin & Expt Med, Czech Republic
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- Helms, Morten (författare)
- Department of Infectious Diseases, Copenhagen University Hospital Hvidovre, Denmark,Copenhagen Univ Hosp Hvidovre, Denmark
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- Kjeldsen, Jens (författare)
- Department of Medical Gastroenterology, Odense University Hospital Research Unit of Medical Gastroenterology, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark,Odense Univ Hosp, Denmark; Univ Southern Denmark, Denmark
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- Rode, Anne A. (författare)
- Department of Medicine, Zealand University Hospital, Køge, Denmark,Zealand Univ Hosp, Denmark
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- Kousgaard, Sabrina Just (författare)
- Department of Gastrointestinal Surgery, Aalborg University Hospital, Aalborg, Denmark,Aalborg Univ Hosp, Denmark
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- Alric, Laurent (författare)
- Department of Internal Medicine and Digestive Diseases, IRD Toulouse 3 University, Toulouse, France,IRD Toulouse 3 Univ, France
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- Trang-Poisson, Caroline (författare)
- Gastroenterology Department, Institut des maladies de l'Appareil Digestif (IMAD), Centre d'investigation Clinique IMAD, University Hospital, Hotel-Dieu, Nantes, France,Hop Hotel Dieu, France
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- Scanzi, Julien (författare)
- French Group of Faecal Microbiota Transplantation (GFTF), Paris, France; Gastroenterology Department, Centre Hospitalier de Thiers, Thiers, France,French Grp Faecal Microbiota Transplantat GFTF, France; Ctr Hosp Thiers, France
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- Link, Alexander (författare)
- Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University, Magdeburg, Germany,Otto von Guericke Univ, Germany
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- Stallmach, Andreas (författare)
- Department of Internal Medicine IV (Gastroenterology, Hepatology, and Infectious Diseases), Jena University Hospital, Jena, Germany,Jena Univ Hosp, Germany
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- Kupcinskas, Juozas (författare)
- Department of Gastroenterology and Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania,Lithuanian Univ Hlth Sci, Lithuania; Lithuanian Univ Hlth Sci, Lithuania
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- Johnsen, Peter Holger (författare)
- University Hospital of North Norway Harstad, Harstad, Norway,Univ Hosp North Norway Harstad, Norway
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- Garborg, Kjetil (författare)
- Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway; Institute of Health and Society, University of Oslo, Oslo, Norway,Oslo Univ Hosp, Norway; Univ Oslo, Norway
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- Rodríguez, Eugenia Sánchez (författare)
- Servicio de Gastroenterología y Hepatología, Hospital Universitario Ramón y Cajal, Madrid, Spain,Hosp Univ Ramon y Cajal, Spain
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- Serrander, Lena (författare)
- Linköpings universitet,Avdelningen för inflammation och infektion,Medicinska fakulteten,Region Östergötland, Klinisk mikrobiologi
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- Brummer, Robert Jan, 1957- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Nutrition-Gut-Brain Interactions Research Centre,Orebro Univ, Sweden
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- Galpérine, Katerina Tatiana (författare)
- French Group of Faecal Microbiota Transplantation (GFTF), Paris, France; Infectious Diseases Service, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland,French Grp Faecal Microbiota Transplantat GFTF, France; Univ Lausanne, Switzerland
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- Goldenberg, Simon D. (författare)
- Centre for Clinical Infection and Diagnostics Research (CIDR), King's College London and Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom,Kings Coll London, England; Guys & St Thomas NHS Fdn Trust, England
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- Mullish, Benjamin H. (författare)
- Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom,Imperial Coll London, England
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- Williams, Horace Rt. (författare)
- Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, United Kingdom,Imperial Coll London, England
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- Iqbal, Tariq H. (författare)
- Department of Gastroenterology, Institute of Immunology and Immunotherapy, University of Birmingham, University Hospital, Birmingham, United Kingdom,Univ Birmingham, England
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- Ponsioen, Cyriel (författare)
- Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, Amsterdam, the Netherlands,Amsterdam Univ Med Ctr, Netherlands
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- Kuijper, Ed J. (författare)
- Netherlands Donor Feces Bank, Leiden University Medical Center, Leiden, the Netherlands; ESCMID Study Group for Host and Microbiota Interaction (ESGHAMI), Basel, Switzerland; Centre for Microbiota Analysis and Therapeutics, Leiden University Medical Centre, Leiden, the Netherlands; National Reference Laboratory for Clostridium difficile, Department of Medical Microbiology, Leiden University Medical Center, Leiden, the Netherlands; National Institute for Public Health and the Environment, Bilthoven, the Netherlands,Leiden Univ Med Ctr, Netherlands; ESCMID Study Grp Host & Microbiota Interact ESGHA, Switzerland; Leiden Univ Med Ctr, Netherlands; Leiden Univ Med Ctr, Netherlands; Natl Inst Publ Hlth & Environm, Netherlands
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- Cammarota, Giovanni (författare)
- Digestive Disease Center, CEMAD, Fondazione Policlinico Universitario Gemelli IRCCS, Rome, Italy,Fdn Policlin Univ Gemelli IRCCS, Italy
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- Keller, Josbert J. (författare)
- Netherlands Donor Feces Bank, Leiden University Medical Center, Leiden, the Netherlands; Department of Gastroenterology, Haaglanden Medical Center, The Hague, the Netherlands; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands,Leiden Univ Med Ctr, Netherlands; Haaglanden Med Ctr, Netherlands; Leiden Univ Med Ctr, Netherlands
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- Hvas, Christian Lodberg (författare)
- Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark,Aarhus Univ Hosp, Denmark
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(creator_code:org_t)
- Elsevier, 2021
- 2021
- Engelska.
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Ingår i: The Lancet Regional Health. - : Elsevier. - 2666-7762. ; 9
- Relaterad länk:
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https://doi.org/10.1...
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https://doi.org/10.1...
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https://liu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background: Faecal microbiota transplantation (FMT) is an emerging treatment modality, but its current clinical use and organisation are unknown. We aimed to describe the clinical use, conduct, and potential for FMT in Europe.Methods: We invited all hospital-based FMT centres within the European Council member states to answer a web-based questionnaire covering their clinical activities, organisation, and regulation of FMT in 2019. Responders were identified from trials registered at clinicaltrials.gov and from the United European Gastroenterology (UEG) working group for stool banking and FMT.Findings: In 2019, 31 FMT centres from 17 countries reported a total of 1,874 (median 25, quartile 10-64) FMT procedures; 1,077 (57%) with Clostridioides difficile infection (CDI) as indication, 791 (42%) with experimental indications, and 6 (0•3%) unaccounted for. Adjusted to population size, 0•257 per 100,000 population received FMT for CDI and 0•189 per 100,000 population for experimental indications. With estimated 12,400 (6,100-28,500) annual cases of multiple, recurrent CDI and indication for FMT in Europe, the current European FMT activity covers approximately 10% of the patients with indication. The participating centres demonstrated high safety standards and adherence to international consensus guidelines. Formal or informal regulation from health authorities was present at 21 (68%) centres.Interpretation: FMT is a widespread routine treatment for multiple, recurrent CDI and an experimental treatment. Embedded within hospital settings, FMT centres operate with high standards across Europe to provide safe FMT. A significant gap in FMT coverage suggests the need to raise clinical awareness and increase the FMT activity in Europe by at least 10-fold to meet the true, indicated need.Funding: NordForsk under the Nordic Council and Innovation Fund Denmark (j.no. 8056-00006B).
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)
Nyckelord
- Abbreviations: CDI
- Clostridioides difficile infection
- Clostridioides difficile
- ECDC
- European Centre for Disease Prevention and Control
- FMT
- FMT
- Faecal microbiota transplantation
- Faecal microbiota transplantation
- IQR
- Interquartile range
- REDCap
- Research Data Capture software
- SARS-CoV-2
- Severe acute respiratory syndrome coronavirus 2
- Stool banking
- UEG
- United Gastroenterology European
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Baunwall, Simon ...
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Terveer, Elisabe ...
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Dahlerup, Jens F ...
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Erikstrup, Chris ...
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Arkkila, Perttu
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Vehreschild, Mar ...
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visa fler...
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Ianiro, Gianluca
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Gasbarrini, Anto ...
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Sokol, Harry
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Kump, Patrizia K ...
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Satokari, Reetta
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De Looze, Danny
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Vermeire, Séveri ...
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Nakov, Radislav
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Brezina, Jan
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Helms, Morten
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Kjeldsen, Jens
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Rode, Anne A.
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Kousgaard, Sabri ...
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Alric, Laurent
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Trang-Poisson, C ...
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Scanzi, Julien
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Link, Alexander
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Stallmach, Andre ...
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Kupcinskas, Juoz ...
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Johnsen, Peter H ...
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Garborg, Kjetil
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Rodríguez, Eugen ...
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Serrander, Lena
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Brummer, Robert ...
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Galpérine, Kater ...
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Goldenberg, Simo ...
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Mullish, Benjami ...
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Williams, Horace ...
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Iqbal, Tariq H.
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Ponsioen, Cyriel
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Kuijper, Ed J.
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Cammarota, Giova ...
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Keller, Josbert ...
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Hvas, Christian ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Gastroenterologi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Hälso och sjukvå ...
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The Lancet Regio ...
- Av lärosätet
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Örebro universitet
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Linköpings universitet