| 1. |
- Kanai, M, et al.
(author)
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- 2023
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swepub:Mat__t
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| 2. |
- Niemi, MEK, et al.
(author)
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- 2021
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swepub:Mat__t
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| 3. |
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| 4. |
- Gassner, Christoph, et al.
(author)
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International Society of Blood Transfusion Working Party on Red Cell Immunogenetics and Blood Group Terminology Report of Basel and three virtual business meetings : Update on blood group systems
- 2022
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In: Vox Sanguinis. - : Wiley. - 1423-0410 .- 0042-9007. ; 117:11, s. 1332-1344
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Journal article (peer-reviewed)abstract
- BACKGROUND AND OBJECTIVES: Under the ISBT, the Working Party (WP) for Red Cell Immunogenetics and Blood Group Terminology is charged with ratifying blood group systems, antigens and alleles. This report presents the outcomes from four WP business meetings, one located in Basel in 2019 and three held as virtual meetings during the COVID-19 pandemic in 2020 and 2021.MATERIALS AND METHODS: As in previous meetings, matters pertaining to blood group antigen nomenclature were discussed. New blood group systems and antigens were approved and named according to the serologic, genetic, biochemical and cell biological evidence presented.RESULTS: Seven new blood group systems, KANNO (defined numerically as ISBT 037), SID (038), CTL2 (039), PEL (040), MAM (041), EMM (042) and ABCC1 (043) were ratified. Two (039 and 043) were de novo discoveries, and the remainder comprised reported antigens where the causal genes were previously unknown. A further 15 blood group antigens were added to the existing blood group systems: MNS (002), RH (004), LU (005), DI (010), SC (013), GE (020), KN (022), JMH (026) and RHAG (030).CONCLUSION: The ISBT now recognizes 378 antigens, of which 345 are clustered within 43 blood group systems while 33 still have an unknown genetic basis. The ongoing discovery of new blood group systems and antigens underscores the diverse and complex biology of the red cell membrane. The WP continues to update the blood group antigen tables and the allele nomenclature tables. These can be found on the ISBT website (http://www.isbtweb.org/working-parties/red-cell-immunogenetics-and-blood-group-terminology/).
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| 5. |
- Capitanio, L., et al.
(author)
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EREBUS: the EuRopean Extinction BUmp Survey
- 2020
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In: Experimental astronomy. - : Springer. - 0922-6435 .- 1572-9508. ; 50:1, s. 145-158
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Journal article (peer-reviewed)abstract
- Dust in the Interstellar Medium (ISM) is intimately linked to the life cycle of stars. Despite being of such fundamental importance to galaxy evolution, the dynamic behaviour and composition of the ISM are not yet fully understood. Observations of reddened Milky Way OB stars have revealed a strong UV extinction feature around 2175 Å and a precipitous extinction rise to the far UV along the lines of sight. Whilst the carrier(s) for this are at present still being debated, multiple laboratory studies suggest carbonate grains to be the key constituent. EREBUS is a mission concept being developed to study the composition of the ISM in both the Milky Way and Local Group Galaxies, primarily by mapping the spatial distribution of the UV extinction features. As these features are sensitive to the dust composition along the line of sight, EREBUS will provide a wealth of information about the spatial distribution and dynamic behaviour of the carrier(s). The mission proposes to deploy a satellite observatory equipped with a coarse UV spectrograph to map the extinction curve variability in the Milky Way in 3 dimensions and in the Local Group in 2 dimensions. In this paper, we discuss the scientific goals for the project, discuss a proposed observation strategy using an iterative process to develop a hierarchical map, and finally outline the instrument requirements and preliminary spacecraft architecture.
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| 6. |
- Gassner, Christoph, et al.
(author)
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Two Prevalent ∼100-kb GYPB Deletions Causative of the GPB-Deficient Blood Group MNS Phenotype S-s-U-in Black Africans
- 2020
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In: Transfusion Medicine and Hemotherapy. - : S. Karger AG. - 1660-3796 .- 1660-3818. ; 47:4, s. 326-336
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Journal article (peer-reviewed)abstract
- The U antigen (MNS5) is one of 49 antigens belonging to the MNS blood group system (ISBT002) carried on glycophorins A (GPA) and B (GPB). U is present on the red blood cells in almost all Europeans and Asians but absent in approximately 1.0% of Black Africans. U negativity coincides with negativity for S (MNS3) and s (MNS4) on GPB, thus be called S-s-U-, and is thought to arise from homozygous deletion of GYPB. Little is known about the molecular background of these deletions. Bioinformatic analysis of the 1000 Genomes Project data revealed several candidate regions with apparent deletions in GYPB. Highly specific Gap-PCRs, only resulting in positive amplification from DNAs with deletions present, allowed for the exact genetic localization of 3 different breakpoints; 110.24- A nd 103.26-kb deletions were proven to be the most frequent in Black Americans and Africans. Among 157 CEPH DNAs, deletions in 6 out of 8 African ethnicities were present. Allele frequencies of the deletions within African ethnicities varied greatly and reached a cumulative 23.3% among the Mbuti Pygmy people from the Congo. Similar observations were made for U+var alleles, known to cause strongly reduced GPB expression. The 110- A nd 103-kb deletional GYPB haplotypes were found to represent the most prevalent hereditary factors causative of the MNS blood group phenotype S-s-U-. Respective GYPB deletions are now accessible by molecular detection of homo- A nd hemizygous transmission.
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| 7. |
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| 8. |
- Kopriva, David A., et al.
(author)
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On the theoretical foundation of overset grid methods for hyperbolic problems : Well-posedness and conservation
- 2022
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In: Journal of Computational Physics. - : ACADEMIC PRESS INC ELSEVIER SCIENCE. - 0021-9991 .- 1090-2716. ; 448
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Journal article (peer-reviewed)abstract
- We use the energy method to study the well-posedness of initial-boundary value problems approximated by overset mesh methods in one and two space dimensions for linear constant-coefficient hyperbolic systems. We show that in one space dimension, for both scalar equations and systems of equations, the problem where one domain partially oversets another is well-posed when characteristic coupling conditions are used. If a system cannot be diagonalized, as is usually the case in multiple space dimensions, then the energy method does not give proper bounds in terms of initial and boundary data. For those problems, we propose a novel penalty approach. We show, by using a global energy that accounts for the energy in the overlap region of the domains, that under well-defined conditions on the coupling matrices the penalized overset domain problems are energy bounded, conservative, well-posed and have solutions equivalent to the original single domain problem.
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| 9. |
- Kopriva, David A., et al.
(author)
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On the theoretical foundation of overset grid methods for hyperbolic problems II : Entropy bounded formulations for nonlinear conservation laws
- 2022
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In: Journal of Computational Physics. - : Elsevier. - 0021-9991 .- 1090-2716. ; 471
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Journal article (peer-reviewed)abstract
- We derive entropy conserving and entropy dissipative overlapping domain formulations for systems of nonlinear hyperbolic equations in conservation form, such as would be approximated by overset mesh methods. The entropy conserving formulation imposes a two-way coupling at the artificial interface boundaries through nonlinear penalty functions that vanish when the solutions coincide. The penalty functions are expressed in terms of entropy conserving fluxes originally introduced for finite volume schemes. In addition to the interface coupling, which is required, entropy dissipation and coupling can optionally be added through the use of linear penalties within the overlap region.
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| 10. |
- Kopriva, David A., et al.
(author)
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Stability of Discontinuous Galerkin Spectral Element Schemes for Wave Propagation when the Coefficient Matrices have Jumps
- 2021
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In: Journal of Scientific Computing. - : Springer. - 0885-7474 .- 1573-7691. ; 88:1
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Journal article (peer-reviewed)abstract
- We use the behavior of the L2 norm of the solutions of linear hyperbolic equations withdiscontinuous coefficient matrices as a surrogate to infer stability of discontinuous Galerkinspectral element methods (DGSEM). Although the L2 norm is not bounded in terms of theinitial data for homogeneous and dissipative boundary conditions for such systems, the L2norm is easier to work with than a norm that discounts growth due to the discontinuities. Weshow that the DGSEM with an upwind numerical flux that satisfies the Rankine–Hugoniot(or conservation) condition has the same energy bound as the partial differential equationdoes in the L2 norm, plus an added dissipation that depends on how much the approximatesolution fails to satisfy the Rankine–Hugoniot jump.
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