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Träfflista för sökning "WFRF:(Geirsson A.) srt2:(2006-2009)"

Sökning: WFRF:(Geirsson A.) > (2006-2009)

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2.
  • Amundadottir, Laufey T., et al. (författare)
  • A common variant associated with prostate cancer in European and African populations
  • 2006
  • Ingår i: Nature Genetics. - DeCODE Genet, IS-101 Reykjavik, Iceland. Univ Iceland, Landspitali Hosp, Dept Pathol, IS-101 Reykjavik, Iceland. Univ Iceland, Landspitali Hosp, Dept Urol, IS-101 Reykjavik, Iceland. Univ Michigan, Dept Human Genet, Ann Arbor, MI 48109 USA. Orebro Univ Hosp, Dept Urol & Clin Med, Orebro, Sweden. Karolinska Inst, Dept Med Epidemiol & Biostat, SE-17177 Stockholm, Sweden. Univ Michigan, Dept Urol, Ann Arbor, MI 48109 USA. Northwestern Univ, Feinberg Sch Med, Dept Urol, Chicago, IL 60611 USA. Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA. Univ Chicago, Dept Human Genet, Chicago, IL 60637 USA. Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA. : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 38:6, s. 652-658
  • Tidskriftsartikel (refereegranskat)abstract
    • With the increasing incidence of prostate cancer, identifying common genetic variants that confer risk of the disease is important. Here we report such a variant on chromosome 8q24, a region initially identified through a study of Icelandic families. Allele -8 of the microsatellite DG8S737 was associated with prostate cancer in three case-control series of European ancestry from Iceland, Sweden and the US. The estimated odds ratio (OR) of the allele is 1.62 (P = 2.7 x 10(-11)). About 19% of affected men and 13% of the general population carry at least one copy, yielding a population attributable risk (PAR) of approximately 8%. The association was also replicated in an African American case-control group with a similar OR, in which 41% of affected individuals and 30% of the population are carriers. This leads to a greater estimated PAR (16%) that may contribute to higher incidence of prostate cancer in African American men than in men of European ancestry.
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3.
  • Hreinsdottir, S, et al. (författare)
  • A complex earthquake sequence captured by the continuous GPS network in SW Iceland
  • 2009
  • Ingår i: Geophysical Research Letters. - 0094-8276 .- 1944-8007. ; 36:12, s. L12309-
  • Tidskriftsartikel (refereegranskat)abstract
    • A complex sequence of earthquakes struck the western part of the South Iceland Seismic Zone (SISZ) on 29 May 2008. The sequence initiated with a M(w)6.3 (NEIC) earthquake in the western part of the SISZ. Aftershocks from the earthquake delineate two parallel N-S trending structures 4 km apart, in addition to activity along an E-W zone further westward. Continuous GPS measurements can best be explained by right-lateral strike-slip motion on two parallel N-S trending faults, with little slip occurring on other structures illuminated by earthquake activity. We estimate a total moment release of M(w)6.2, with M(w)6.1 on the first rupture and M(w)6.0 on the second rupture. High rate (1 Hz) CGPS data from a near-field station suggest that the main asperity on the Kross fault ruptured within 3 s of the initial mainshock on the Ingolfsfjall fault. Citation: Hreinsdottir, S., T. Amadottir, J. Decriem, H. Geirsson, A. Tryggvason, R. A. Bennett, and P. LaFemina (2009), A complex earthquake sequence captured by the continuous GPS network in SW Iceland, Geophys. Res. Lett., 36, L12309, doi: 10.1029/2009GL038391.
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