| 1. |
- Elsik, Christine G., et al.
(författare)
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The Genome Sequence of Taurine Cattle : A Window to Ruminant Biology and Evolution
- 2009
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 324:5926, s. 522-528
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Tidskriftsartikel (refereegranskat)abstract
- To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.
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| 2. |
- Kaput, J, et al.
(författare)
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The case for strategic international alliances to harness nutritional genomics for public and personal health
- 2005
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Ingår i: The British journal of nutrition. - : Cambridge University Press (CUP). - 0007-1145 .- 1475-2662. ; 94:5, s. 623-632
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Tidskriftsartikel (refereegranskat)abstract
- Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene–nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need for new methodologies and the use of comprehensive analyses of nutrient–genotype interactions involving large and diverse populations. The objective of the present paper is to stimulate discourse and collaboration among nutrigenomic researchers and stakeholders, a process that will lead to an increase in global health and wellness by reducing health disparities in developed and developing countries.
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| 3. |
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| 4. |
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| 5. |
- Jansons, K., et al.
(författare)
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Modelling of different measures for improving removal in a storm pond
- 2005
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Ingår i: Water Science and Technology. - 1996-9732 .- 0273-1223. ; 52:5, s. 105-112
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Tidskriftsartikel (refereegranskat)abstract
- The effect of retrofitting an existing pond on removal efficiency and hydraulic performance was modelled using the commercial software Mike21 and compartmental modelling. The Mike21 model had previously been calibrated on the studied pond. Installation of baffles, the addition of culverts under a causeway and removal of an existing island were all studied as possible improvement measures in the pond. The subsequent effect on hydraulic performance and removal of. suspended solids was then evaluated. Copper, cadmium, BOD, nitrogen and phosphorus removal were,also investigated for that specific improvement measure showing the best results. Outcomes of this study reveal that all measures increase the removal efficiency of suspended solids. The hydraulic efficiency is improved for all cases, except for the case where the island is removed. Compartmental modelling was also used to evaluate hydraulic performance and facilitated a better understanding of the way each of the different measures affected the flow pattern and performance. It was concluded that the installation of baffles is the best of the studied measures resulting in a reduction in the annual load on the receiving lake by approximately 8,000 kg of suspended solids (25% reduction of the annual load), 2 kg of copper (10% reduction of the annual load) and 600 kg of BOD (10% reduction of the annual load).
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| 6. |
- Salazar-Alvarez, German, et al.
(författare)
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Enhanced coercivity in Co-rich near-stoichiometric CoFe3-xO4+delta nanoparticles prepared in large batches
- 2007
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Ingår i: Chemistry of Materials. - : American Chemical Society (ACS). - 0897-4756 .- 1520-5002. ; 19:20, s. 4957-4963
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Tidskriftsartikel (refereegranskat)abstract
- The relationship between the structure and composition with the magnetic properties of near stoichiometric cobalt ferrite nanoparticles CoxFe3-xO4+delta (0.85 < x < 1.1) prepared in large batches with average sizes in the range 60-210 nm has been investigated. Chemical analysis and Rietveld refinement of the X-ray diffraction data in conjunction with Mossbauer spectroscopy allowed us to identify an interplay between particle size, microstructure (concentration of interstitial ions, microstrain, cation arrangement in octahedral and tetrahedral sites), and composition, which sensitively controls the magnetic properties such as coercivity and saturation magnetization. In all cases, cobalt-rich compositions resulted in a higher coercivity, whereas lower degrees of inversion and higher iron contents led to slightly higher saturation magnetization values.
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