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- Wänman, Johan, et al.
(författare)
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Predictive Value of the Spinal Instability Neoplastic Score for Survival and Ambulatory Function After Surgery for Metastatic Spinal Cord Compression in 110 Patients with Prostate Cancer
- 2021
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Ingår i: Spine. - : Wolters Kluwer. - 0362-2436 .- 1528-1159. ; 46:8, s. 550-558
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Tidskriftsartikel (refereegranskat)abstract
- STUDY DESIGN: We retrospectively analyzed Spinal Instability Neoplastic Score (SINS) in 110 patients with prostate cancer operated for metastatic spinal cord compression (MSCC). OBJECTIVE: We aimed to investigate the association between SINS and clinical outcomes after surgery for MSCC in patients with prostate cancer. SUMMARY OF BACKGROUND DATA: The SINS is a useful tool for assessing tumor-related spinal instability, but its prognostic value regarding survival and neurological outcome is still controversial. METHODS: We analyzed 110 consecutive patients with prostate cancer who underwent surgery for MSCC. The patients were categorized according to their SINS. Patients with castration-resistant prostate cancer (CRPC, n = 84) and those with hormone-naïve disease (n = 26) were analyzed separately. RESULTS: In total, 106 of 110 patients met the SINS criteria for potential instability or instability (scores 7-18). The median SINS was 10 (range 6-15) for patients with CRPC and 9 (7-16) for hormone-naïve patients. In the CRPC group, the SINS was classified as stable (score 0-6) in 4 patients, as potentially unstable (score 7-12) in 70 patients, and as unstable (score 13-18) in 10 patients. In the hormone-naïve group, 22 patients met the SINS criteria for potential instability and 4 patients for instability. There was no statistically significant difference in the overall risk for death between the SINS potentially unstable and unstable categories (adjusted hazard ratio 1.3, P = 0.4), or in the risk of loss of ambulation 1 month after surgery (adjusted odds ratio 1.4, P = 0.6). CONCLUSION: The SINS is helpful in assessing spinal instability when selecting patients for surgery, but it does not predict survival or neurological outcomes. Patients with a potential spinal instability benefit equally from surgery for MSCC as do patients with spinal instability.Level of Evidence: 3.
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| 2. |
- Grabowski, Radoslaw
(författare)
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Burnt grain and crop cleaning residues: An archaeobotanical contribution to the understanding of 3rd–6th century ad longhouses in jutland and funen (Denmark)
- 2020
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Ingår i: Interdisciplinaria Archaeologica. - : Archeologicke Centrum Olomouc. - 1804-848X .- 2336-1220. ; 11:1, s. 47-62
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Tidskriftsartikel (refereegranskat)abstract
- This paper uses the composition and spatial distribution of carbonised archaeobotanical material from postholes to identify and delineate agrarian and household activities within settlements. The paper presents the analyses of seven houses/farmsteads dating to the 3rd–6th century AD, which were excavated on four separate sites: Flensted, Skovby Nygård and Gedved Vest in east-central Jutland, and Odensevej on the island of Funen. To infer settlement activities from the distributions of carbonised plant macro remains, the paper defines the various stages of plant processing and carbonisation circumstances. It also discusses assumptions about plant processing sequences and the formation of charred plant assemblages that were made during the analysis. The results show that the distribution of charred plant macro-remains can assist in the identification and delineation of spaces with different functions. The presented cases identify the locations of dwelling spaces, spaces where processed crops were stored and/or used, and spaces where fine sieving of grain was performed. The results also show a similarity between the analysed houses, which suggests the existence of a regional tradition of ordering household space. These patterns also confirm assumptions about mid-1st millennium houses previously made on the basis of other archaeological evidence.
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| 3. |
- Grabowski, Radoslaw, et al.
(författare)
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The use of space on two Early Iron Age house sites in South-West Jutland, South Scandinavia : A geoarchaeological multiproxy approach
- 2022
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Ingår i: Journal of Archaeological Science. - : Elsevier. - 2352-409X .- 2352-4103. ; 42
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Tidskriftsartikel (refereegranskat)abstract
- This paper describes analyses for understanding the general use of space on two Early Iron Age house sites on the site of Sønderris in South-West Jutland (South Scandinavia). The main method consists of the geoarchaeological techniques of soil P analysis by citric acid extraction, low frequency magnetic susceptibility analysis, and measurement of the soils organic content by loss-on-ignition. The results of these analyses are, moreover, interpreted alongside artefact distribution data, data on the dispersal of plant macrofossils, and an evaluation of the architectural details of the sites.At both house sites, the geoarchaeological data shows patterning indicative of human activities. The main achievements are inference of outdoor areas which may have contained pyres or kilns, delineation of yard spaces with refuse deposition, and the characterisation of functional aspects of two small outbuildings. In general, the geoarchaeological results are consistent with the inferences attained from non-geoarchaeological sources. A notable exception is that few clear traces of stalling were identified in the geoarchaeological record, despite the presence of animal booth partition walls indicating the presence of byres in the longhouses. Possible reasons for this are discussed.Overall, this study demonstrates the continued usefulness of long-established geoarchaeological methods for gaining insights about the nature, extent, and orientation of activities on prehistoric house sites. A key take-away from the study is that the potential of any individual method for reading activities (geoarchaeological or otherwise), increases when several techniques with overlapping, but not identical, scope for inferring activities are integrated. The resulting multiproxy analysis is, as a whole, more useful than the sum of its constituent parts.
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