| 1. |
|
|
| 2. |
|
|
| 3. |
- Brown, Harvey R., et al.
(författare)
-
Remarks on identical particles in de Broglie-Bohm theory
- 1999
-
Ingår i: Physics Letters A. - 0375-9601 .- 1873-2429. ; 251:4, s. 229-235
-
Tidskriftsartikel (refereegranskat)abstract
- It is argued that the topological approach to the (anti-) symmetrisation condition for the quantum state of a collection of identical particles, defined in the "reduced" configuration space, is particularly natural from the perspective of de Broglie-Bohm pilot-wave theory.
|
|
| 4. |
- Brown, J, et al.
(författare)
-
Frontotemporal dementia linked to chromosome 3
- 2004
-
Ingår i: Dementia and Geriatric Cognitive Disorders. - : S. Karger AG. - 1420-8008 .- 1421-9824. ; 17:4, s. 274-276
-
Tidskriftsartikel (refereegranskat)abstract
- A large pedigree with autosomal dominant frontotemporal dementia has been identified. Positional cloning has linked the disease gene to the pericentromeric region of chromosome 3. Clinical, neuropsychological, imaging, pathological and molecular genetic data are presented. The genetic mutation responsible for the disease has not been identified.
|
|
| 5. |
- Rousk, Johannes, et al.
(författare)
-
Fungal and bacterial growth responses to N fertilization and pH in the 150-year 'Park Grass' UK grassland experiment.
- 2011
-
Ingår i: FEMS Microbiology Ecology. - : Oxford University Press (OUP). - 1574-6941 .- 0168-6496. ; 76, s. 89-99
-
Tidskriftsartikel (refereegranskat)abstract
- The effects of nitrogen (N) fertilization (0-150 kg N ha(-1) year(-1) since 1865) and pH (3.3-7.4) on fungal and bacterial growth, biomass and phospholipid fatty acid (PLFA) composition were investigated in grassland soils from the 'Park Grass Experiment', Rothamsted Research, UK. Bacterial growth decreased and fungal growth increased with lower pH, resulting in a 50-fold increase in the relative importance of fungi between pH 7.4 and 3.3. The PLFA-based fungal : bacterial biomass ratio was unchanged between pH 4.5 and 7.4, and decreased only below pH 4.5. Respiration and substrate-induced respiration biomass both decreased three- to fourfold with lower pH, but biomass concentrations estimated using PLFAs were unaffected by pH. N fertilization did not affect bacterial growth and marginally affected fungal growth while PLFA biomass marker concentrations were all reduced by higher N additions. Respiration decreased with higher N application, suggesting a reduced quality of the soil organic carbon. The PLFA composition was strongly affected by both pH and N. A comparison with a pH gradient in arable soil allowed us to generalize the pH effect between systems. There are 30-50-fold increases in the relative importance of fungi between high (7.4-8.3) and low (3.3-4.5) pH with concomitant reductions of respiration by 30-70%.
|
|
| 6. |
|
|
| 7. |
- Diekstra, Frank P., et al.
(författare)
-
UNC13A is a modifier of survival in amyotrophic lateral sclerosis
- 2012
-
Ingår i: Neurobiology of Aging. - : Elsevier. - 0197-4580 .- 1558-1497. ; 33:3, s. 630.e3-630.e8
-
Tidskriftsartikel (refereegranskat)abstract
- A large genome-wide screen in patients with sporadic amyotrophic lateral sclerosis (ALS) showed that the common variant rs12608932 in gene UNC13A was associated with disease susceptibility. UNC13A regulates the release of neurotransmitters, including glutamate. Genetic risk factors that, in addition, modify survival, provide promising therapeutic targets in ALS, a disease whose etiology remains largely elusive. We examined whether UNC13A was associated with survival of ALS patients in a cohort of 450 sporadic ALS patients and 524 unaffected controls from a population-based study of ALS in The Netherlands. Additionally, survival data were collected from individuals of Dutch, Belgian, or Swedish descent (1767 cases, 1817 controls) who had participated in a previously published genome-wide association study of ALS. We related survival to rs12608932 genotype. In both cohorts, the minor allele of rs12608932 in UNC13A was not only associated with susceptibility but also with shorter survival of ALS patients. Our results further corroborate the role of UNC13A in ALS pathogenesis. (C) 2012 Elsevier Inc. All rights reserved.
|
|
| 8. |
- Ribul, Miriam, et al.
(författare)
-
The Material Affinity of Design and Science for a Circular Economy
- 2016
-
Ingår i: Circular Transitions Proceedings. ; , s. 236-248
-
Konferensbidrag (refereegranskat)abstract
- This paper presents a design and material science collaboration in a science laboratory for regenerated cellulose. The material affinity outlines how both disciplines are connected through a materials practice in communication and production of cellulose films. The outcome presents new transdisciplinary approaches for design and science towards circularity of materials.
|
|
| 9. |
- Sá, Juliana, et al.
(författare)
-
Transiciones en la educación médica : llenando los espacios en blanco
- 2021
-
Ingår i: Educacion Medica. - : Elsevier BV. - 1575-1813. ; 22:6, s. 346-351
-
Tidskriftsartikel (refereegranskat)abstract
- Transitions in medical education are moments of intense learning, bringing significant challenges for the trainees, the medical programs and healthcare provision. Frequently, transitional periods are not prepared or mentored; this process of transformation in the trainee is left to occur by chance and opportunity. Promotion of medical education continuity requires formal support in the continuous process of learning and professionalization. This is a review of the formal transitional periods in medical education considering the most significant points of transition. The challenges of each period of transition are analyzed and strategies for improvement are discussed. Educational strategies should not be directly translated to other settings; however, they need to be adapted to the cultural context of medical training to be effective. Research on transitions, considering the socialization process and the cultural environment, should be performed to better support the medical professional pathway.
|
|
