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Träfflista för sökning "WFRF:(Gu F) srt2:(1996-1999)"

Search: WFRF:(Gu F) > (1996-1999)

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1.	Bauren, G, et al. (author) Demonstration of a dynamic, transcription-dependent organization of pre-mRNA splicing factors in polytene nuclei 1996 In: The Journal of cell biology. - : Rockefeller University Press. - 0021-9525 .- 1540-8140. ; 133:5, s. 929-941 Journal article (peer-reviewed)abstract We describe the dynamic organization of pre-mRNA splicing factors in the intact polytene nuclei of the dipteran Chironomus tentans. The snRNPs and an SR non-snRNP splicing factor are present in excess, mainly distributed throughout the interchromatin. Approximately 10% of the U2 snRNP and an SR non-snRNP splicing factor are associated with the chromosomes, highly enriched in active gene loci where they are bound to RNA. We demonstrate that the splicing factors are specifically recruited to a defined gene upon induction of transcription during physiological conditions. Concomitantly, the splicing factors leave gene loci in which transcription is turned off. We also demonstrated that upon general transcription inhibition, the splicing factors redistribute from active gene loci to the interchromatin. Our findings demonstrate the dynamic intranuclear organization of splicing factors and a tight linkage between transcription and the intranuclear organization of the splicing machinery.
2.	Gu, F, et al. (author) Primed in situ labeling (PRINS) detection of the telomeric (CCCTAA) sequences in chromosomes of domestic animals 1996 In: Mammalian genome : official journal of the International Mammalian Genome Society. - : Springer Science and Business Media LLC. - 0938-8990. ; 7:3, s. 231-232 Journal article (peer-reviewed)
3.	Gu, H F, et al. (author) Using PRINS for gene mapping in polytene chromosomes. 1997 In: Chromosome Res. - 0967-3849. ; 5:7, s. 463-5 Journal article (peer-reviewed)

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Type of publication: journal article (3)

Type of content: peer-reviewed (3)

Author/Editor: Wieslander, L (2); Gu, F (2); Landegren, U (1); Melefors, O (1); Söderhäll, K (1); Bauren, G (1); show more...; Jiang, WQ (1); Bernholm, K (1); Hindkjaer, J (1); Gu, H F (1); Lind, M I (1); show less...

University: Karolinska Institutet (3); Uppsala University (1)

Language: English (3)

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