HIV-1 protease inhibitors based on acyclic carbohydrates

• A series of acyclic C2-symmetric HIV protease inhibitors readily accessible from D-mannitol have been developed. Several of the compounds synthesized showed significant in vitro activity against HIV-1 protease.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Farmaceutiska vetenskaper (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Pharmaceutical Sciences (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)

Nyckelord

HUMAN-IMMUNODEFICIENCY-VIRUS; BETA-D-GLUCOSE; D-MANNITOL; GLYCIDYL DERIVATIVES; VIRAL INFECTIVITY; AIDS; DRUGS; PEPTIDOMIMETICS; SYMMETRY; DESIGN

PHARMACY

FARMACI

Biochemistry

Biokemi

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