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| 2. |
- Abul-Kasim, Kasim, et al.
(författare)
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Low-dose helical computed tomography (CT) in the perioperative workup of adolescent idiopathic scoliosis.
- 2009
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Ingår i: European Radiology. - : Springer Science and Business Media LLC. - 0938-7994 .- 1432-1084. ; 19, s. 610-618
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Tidskriftsartikel (refereegranskat)abstract
- The study aims were to estimate the radiation dose in patients examined with low dose spine CT and to compare it with that received by patients undergoing standard CT for trauma of the same region, as well as to evaluate the impact of dose reduction on image quality. Radiation doses in 113 consecutive low dose spine CTs were compared with those in 127 CTs for trauma. The inter- and intraobserver agreement in measurements of pedicular width, and vertebral rotation, measurements of signal-to-noise ratio and assessment of hardware status were the indicators in the evaluation of image quality. The effective dose of the low dose spine CT (0.37 mSv) was 20 times lower than that of a standard CT for trauma (13.09 mSv). This dose reduction conveyed no impact on image quality. This low dose spine CT protocol allows detailed evaluation that is necessary for preoperative planning and postoperative evaluation.
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| 3. |
- Abul-Kasim, Kasim, et al.
(författare)
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Radiation dose optimization in CT planning of corrective scoliosis surgery. A phantom study.
- 2008
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Ingår i: The Neuroradiology Journal. ; 21:3, s. 374-382
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Tidskriftsartikel (refereegranskat)abstract
- The aim of the study was to explore the possibility of obtaining a helical CT scan of a long segment of vertebral column, optimally reduce the radiation dose, compare the radiation dose of the low dose helical CT with that of some of the CT protocols used in clinical practice and finally assess the impact of such a dose reduction on the image quality. A chest phantom was examined with a 16-slice CT scanner. Six scans were performed with different radiation doses. The lowest radiation dose which had no impact on image quality with regard to the information required for surgical planning of patients with scoliosis, was 20 times lower than that of routinely used protocol for CT examination of the spine in children (0.38 mSv vs 7.76 mSv). Patients with scoliosis planned for corrective spinal surgery can be examined with low dose helical CT scan. The dose reduction systems (DRS) available in modern CT scanners contribute to dose reduction and should be used.
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| 4. |
- Alegret, Joan, 1977, et al.
(författare)
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Plasmonic properties of silver trimers with trigonal symmetry fabricated by electron-beam lithography
- 2008
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Ingår i: Journal of Physical Chemistry C. - : American Chemical Society (ACS). - 1932-7447 .- 1932-7455. ; 112:37, s. 14313-14317
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Tidskriftsartikel (refereegranskat)abstract
- We investigate the dipolar plasmon modes of nanoparticle trimers formed by three equal silver disks of diameter D = 100 nm located on the vertexes of an equilateral triangle. Samples were fabricated by electron-beam lithography and studied experimentally by dark-field spectroscopy. The results are found to be in good agreement with electrodynamical simulations based on the discrete dipole approximation (DDA). Similar to nanoparticle dimers, the trimer system exhibits two hybridized dipole resonances to the red and to the blue of the single particle resonance. However, the far-field spectra are polarization-insensitive for light incident normal to the plane of the trimer, and the peak shifts, which occur as the edge-to-edge distance d between the particles decrease, are smaller than for dimers. Moreover, we find that the dipolar displacement patterns are well described by linear combinations of bonding and antibonding symmetry adapted coordinates obtained through symmetry analysis based on the ideal D-3h point-group.
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| 5. |
- Chen, Si, 1985, et al.
(författare)
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Ultrahigh sensitivity made simple : nanoplasmonic label-free biosensing with an extremely low limit-of-detection for bacterial and cancer diagnostics.
- 2009
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Ingår i: Nanotechnology. - : Institute of Physics (IOP). - 0957-4484 .- 1361-6528. ; 20:43
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Tidskriftsartikel (refereegranskat)abstract
- We present a simple and robust scheme for biosensing with an ultralow limit-of-detection down to several pg cm(-2) (or several tens of attomoles cm(-2)) based on optical label-free biodetection with localized surface plasmon resonances. The scheme utilizes cost-effective optical components and comprises a white light source, a properly functionalized sensor surface enclosed in a simple fluidics chip, and a spectral analyzer. The sensor surface is produced by a bottom-up nanofabrication technique with hole mask colloidal lithography. Despite its simplicity, the method is able to reliably detect protein-protein binding events at low picomolar and femtomolar concentrations, which is exemplified by the label-free detection of the extracellular adherence protein (EAP) found on the outer surface of the bacterium Staphylococcus aureus and of prostate-specific antigen (PSA), which is believed to be a prostate cancer marker. These experiments pave the way towards an ultra-sensitive yet compact biodetection platform for point-of-care diagnostics applications.
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| 6. |
- Dahlin, Andreas, 1980, et al.
(författare)
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High-Resolution Microspectroscopy of Plasmonic Nanostructures for Miniaturized Biosensing
- 2009
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Ingår i: Analytical Chemistry. - : American Chemical Society. - 0003-2700 .- 1520-6882. ; 81:16, s. 6572-6580
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Tidskriftsartikel (refereegranskat)abstract
- In this article, we demonstrate how to perform microscale spectroscopy of plasmonic nanostructures in order to minimize the noise when determining the resonance peak wavelength. This is accomplished using an experimental setup containing standard optical components mounted on an ordinary light microscope. We present a detailed comparison between extinction spectroscopy in transmission mode and scattering spectroscopy under dark field illumination, which shows that extinction measurements provide higher signal-to-noise in almost all situations. Furthermore, it is shown that rational selection of nanostructure, hardware components, and data analysis algorithms enables tracking of the particle plasmon resonance wavelength from a 10 mu m x 50 mu m area with a resolution of 10(-3) nm in transmission mode. We investigate how the temporal resolution, which can be improved down to 17 Ins, affects, the noise characteristics. In addition, we show how data can be acquired from an area as small as 2 mu m x 10 mu m (similar to 240 particles) at the expense of higher noise on longer time scales. In comparison with previous work on macroscopic sensor designs, this represents a sensor miniaturization of 5 orders of magnitude, without any loss in signal-to-noise performance. As a model system, we illustrate biomolecular detection using gold nanodisks prepared by colloidal lithography. The microextinction measurements of nanodisks described here provide detection of protein surface coverages as low as 40 pg/cm(2) (less than0.1% of saturated binding). In fact, the miniaturized system provides a detection limit in terms of surface coverage comparable to state of the art macroscopic sensors, while simultaneously being as close to single protein molecule detection as sensors based on a single nanoparticle.
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| 7. |
- Ekelund, L, et al.
(författare)
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Imaging of Four-Corner Fusion (SLAC Arthrodesis) of the Wrist with 64-Slice Computed Tomography.
- 2007
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Ingår i: Acta Radiologica. - : SAGE Publications. - 1600-0455 .- 0284-1851. ; 48:1, s. 76-79
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: To find out whether it is possible to evaluate the healing of wrist arthrodesis, carried out with a metallic spider plate, by means of 64-slice computed tomography (CT). Material and Methods: 18 CT examinations were performed in 12 patients 2 weeks to 37 months following scapholunate advanced collapse (SLAC) arthrodesis fixed with a metallic plate. Ten patients also had plain films of the wrist. Radiation doses were estimated. Results: Plain films were difficult to evaluate due to overprojection of the spider plate. With 64-slice CT, however, it was possible to evaluate the healing process in all patients in spite of metallic artifacts. Radiation doses were low. Conclusion: The healing of SLAC arthrodesis of the wrist is difficult to evaluate with conventional radiography due to the metallic plate. By means of 64-slice CT, however, it was possible to “see under” the plate in all 12 patients.
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| 8. |
- Enqvist, Martin, 1976-, et al.
(författare)
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The CDIO Initiative from an Automatic Control Project Course Perspective
- 2005
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Ingår i: Proceedings of the 16th IFAC World Congress. - 9783902661753 ; , s. 2283-2283
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Konferensbidrag (refereegranskat)abstract
- The CDIO (Conceive Design Implement Operate) Initiative is explained, and some of the results at the Applied Physics and Electrical Engineering program at Linköping University, Sweden, are presented. A project course in Automatic Control is used as an example. The projects within the course are carried out using the LIPS (Linköping interactive project steering) model. An example of a project, the golf playing industrial robot, and the results from this project are also covered.
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| 9. |
- Fujimori, Atsushi, et al.
(författare)
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A Gain Scheduling Control of Nonlinear Systems along a Reference Trajectory
- 2005
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Ingår i: Proceedings of the 16th IFAC World Congress. - 9783902661753 ; , s. 609-609
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Konferensbidrag (refereegranskat)abstract
- This paper presents a gain scheduling control of a nonlinear system in which the reference trajectory is given in advance. Multiple frozen operating times are chosen on the reference trajectory and a linear time invariant model is obtained at each operating time. A linear parameter varying model is then constructed by interpolating the region between the neighbor frozen operating times. A gain scheduling state feedback law is designed by a linear matrix inequality formulation. The effectiveness is demonstrated in a numerical simulation of a traing control of a two-link robot arm.
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