| 1. |
- Anderson, Nils-Eric, 1955, et al.
(författare)
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Storsatsning på Hantverkskunnandet
- 2012
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Ingår i: Byggindustrin 2012-08-22. - 1104-5981.
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Certifiering gesäll- och mästarbrev för murare finns med i en satsning ned syfte att stärka hantverkarrollen på mur- och putsområdet. Detta skulle kunna stå modell för liknande arbetet på andra håll inom byggsektorn, anser byggnadskonstruktören Tomas Gustavsson och lektorn Nils-Eric Anderson
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| 2. |
- Ring, M., et al.
(författare)
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Arterial Structure and Function in Mild Primary Hyperparathyroidism Is Not Directly Related to Parathyroid Hormone, Calcium, or Vitamin D
- 2012
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Ingår i: PLoS ONE. - 1932-6203. ; 7:7
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Elevated levels of calcium and parathyroid hormone (PTH), characteristics of primary hyperparathyroidism (PHPT), may be associated with cardiovascular morbidity and mortality in the general population. We evaluated the possible vascular effects of these risk factors in patients with mild PHPT by using standard methods and new imaging techniques. Design: A prospective case-control study. Subjects and Methods: Forty-eight patients with mild PHPT without any known cardiovascular risk factors were studied at baseline and at one year after parathyroidectomy (PTX) in comparison with 48 healthy age-and gender-matched controls. We measured biochemical variables, augmentation index (AIx), aortic pulse wave velocity (PWVao), radial (IMTrad) and common carotid artery (IMTcca) intima media thicknesses, and the grayscale median (IM-GSM) of the latter. Results: No significant differences were observed between PHPT patients and controls at baseline for AIx (28.6+/-12.2 vs. 27.7+/-12.8%), IMTrad (0.271+/-0.060 vs. 0.255+/-0.053 mm), IMTcca (0.688+/-0.113 vs. 0.680+/-0.135 mm), or IM-GSM (82.3+/-17.2 vs. 86.5+/-15.3), while PWVao was slightly higher in patients (8.68+/-1.50 vs. 8.13+/-1.55, p<0.05). Systolic blood pressure (SBP), calcium, and PTH were higher in patients compared with controls, and decreased after PTX, while vitamin D was lower in patients and increased after PTX. While AIx, PWVao, IMTrad, and IMTcca were related to SBP, neither correlated to vitamin D levels. Only PWVao correlated weakly to plasma PTH (r=0.29, p<0.01) and ionized calcium (r=0.22, p<0.05) but showed no relation when age and SBP were adjusted for. Conclusion: We found normal arterial function despite high calcium, PTH, and low vitamin D levels, in patients with mild PHPT without cardiovascular risk factors. The cardiovascular risk associated with low vitamin D and/or high PTH and calcium levels may be explained by their coupling to blood pressure and other risk factors rather than direct effects on arterial structure.
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| 3. |
- Ring, M., et al.
(författare)
-
Arterial Structure and Function in Mild Primary Hyperparathyroidism Is Not Directly Related to Parathyroid Hormone, Calcium, or Vitamin D
- 2012
-
Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203 .- 1932-6203. ; 7:7, s. Art. no. e39519-
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Elevated levels of calcium and parathyroid hormone (PTH), characteristics of primary hyperparathyroidism (PHPT), may be associated with cardiovascular morbidity and mortality in the general population. We evaluated the possible vascular effects of these risk factors in patients with mild PHPT by using standard methods and new imaging techniques.Design: A prospective case-control study.Subjects and Methods: Forty-eight patients with mild PHPT without any known cardiovascular risk factors were studied at baseline and at one year after parathyroidectomy (PTX) in comparison with 48 healthy age-and gender-matched controls. We measured biochemical variables, augmentation index (AIx), aortic pulse wave velocity (PWVao), radial (IMTrad) and common carotid artery (IMTcca) intima media thicknesses, and the grayscale median (IM-GSM) of the latter.Results: No significant differences were observed between PHPT patients and controls at baseline for AIx (28.6+/-12.2 vs. 27.7+/-12.8%), IMTrad (0.271+/-0.060 vs. 0.255+/-0.053 mm), IMTcca (0.688+/-0.113 vs. 0.680+/-0.135 mm), or IM-GSM (82.3+/-17.2 vs. 86.5+/-15.3), while PWVao was slightly higher in patients (8.68+/-1.50 vs. 8.13+/-1.55, p
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| 4. |
- Sundholm, Johnny, et al.
(författare)
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Semi-automatic border detection software for the quantification of arterial lumen, intima-media and adventitia layer thickness with very-high resolution ultrasound
- 2014
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Ingår i: Atherosclerosis. - : Elsevier BV. - 1879-1484 .- 0021-9150. ; 234:2, s. 283-287
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Tidskriftsartikel (refereegranskat)abstract
- Background: The aim was to evaluate the accuracy, precision and feasibility of semi-automatic border detection software (AMS) in comparison to manual electronic calipers (EC) in the analysis of arterial images obtained with transcutaneous very-high resolution vascular ultrasound (VHRU, 25-55 MHz). Methods: 100 images from central elastic and peripheral muscular arteries were obtained on two separate imaging occasions from 10 healthy subjects, and independently measured with AMS and EC. Results: No bias between AMS and EC was found. The intraobserver coefficients of variation (CV) for carotid lumen dimension (mean dimension 5.60 mm) was lower with AMS compared with EC (0.4 vs. 1.9%, p = 0.033; N = 20). No consistently significant differences in intra, inter or test-retest CVs were observed overall for muscular artery dimensions between AMS and EC. The intra CV for adventitial thickness (AT, mean 0.111 mm; 15.6 vs 24.8%, p = 0.011; N 41) and inter CV for intima-media thickness (IMT, mean 0.219 mm; 14.3 vs. 21.2%, p = 0.001; N = 58) obtained with AMS in higher quality thin muscular artery images was lower compared with EC. The mean reading time was significantly lower with AMS compared with EC (71.5 s vs. 156.6 s, p
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| 5. |
- Yousry, M., et al.
(författare)
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Real-time imaging required for optimal echocardiographic assessment of aortic valve calcification
- 2012
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Ingår i: Clinical Physiology and Functional Imaging. - 1475-0961 .- 1475-097X. ; 32:6, s. 470-475
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Tidskriftsartikel (refereegranskat)abstract
- Introduction Aortic valve calcification (AVC), even without haemodynamic significance, may be prognostically import as an expression of generalized atherosclerosis, but techniques for echocardiographic assessment are essentially unexplored. Methods Two-dimensional (2D) echocardiographic recordings (Philips IE33) of the aortic valve in short-axis and long-axis views were performed in 185 consecutive patients within 1 week before surgery for aortic stenosis (n = 109, AS), aortic regurgitation (n = 61, AR), their combination (n = 8) or dilation of the ascending aorta (n = 7). The grey scale mean (GSMn) of the aortic valve in an end-diastolic short-axis still frame was measured. The same frame was scored visually 15 as indicating that the aortic valve was normal, thick, or had mild, moderate or severe calcification. The visual echodensity of each leaflet was determined real time applying the same 5-grade scoring system for each leaflet, and the average for the whole valve was calculated. Finally, a similar calcification score for the whole valve based on inspection and palpation by the surgeon was noted. Results Visual assessment of real-time images using the proposed scoring system showed better correlation with the surgical evaluation of the degree of valve calcification (r = 0.83, P<0.001) compared to evaluation of stop frames by visual assessment (r = 0.66, P<0.001) or the GSMn score (r = 0.64, P<0.001). High inter- and intra-observer correlations were observed for real-time visual score (both intraclass correlation coefficient = 0.93). Conclusion Real-time evaluation of the level of AVC is superior to using stop frames assessed either visually or by dedicated computer grey scale measurement software.
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