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Sökning: WFRF:(Ha Nguyen Thanh) > (2020-2024)

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1.
  • Nguyen, Thanh-Nha, et al. (författare)
  • Gender relations and social media : a grounded theory inquiry of young Vietnamese women’s self-presentations on Facebook
  • 2020
  • Ingår i: Gender, Technology and Development. - : Taylor & Francis. - 0971-8524 .- 0973-0656. ; 24:2, s. 174-193
  • Tidskriftsartikel (refereegranskat)abstract
    • Since the introduction of Đổi Mới (market economic reforms) in 1986, Vietnam has experienced rapid social, cultural, economic and technological changes. The purpose of this study is to explore the nexus between gender relations and social media with a focus on how young urban Vietnamese women present themselves on Facebook. Grounded theory was employed to inquire into this phenomenon, revealing that the participants use various self-presentation techniques (strategies) including an ideal appearance, competency (mastery) and a positive image. The participants’ self-presentations were found to be simultaneously influenced by Confucian ethics, socialist ideology and neoliberal global culture. The intersection of these social forces has changed the nature of gender relations and expectations for young Vietnamese women, leading to the emergence of a neoliberal gendered self in their presentations on Facebook. This study foregrounds how gender relations in early twenty-first century Vietnam are being reconfigured by competing values and how these can be analyzed through and influenced by social media use.
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2.
  • Pham, Em Canh, et al. (författare)
  • N,2,6-Trisubstituted 1H-benzimidazole derivatives as a new scaffold of antimicrobial and anticancer agents : design, synthesis, in vitro evaluation, and in silico studies
  • 2023
  • Ingår i: RSC Advances. - : Royal Society of Chemistry. - 2046-2069. ; 13:1, s. 399-420
  • Tidskriftsartikel (refereegranskat)abstract
    • Compounds containing benzimidazole moiety occupy privileged chemical space for discovering new bioactive substances. In continuation of our recent work, 69 benzimidazole derivatives were designed and synthesized with good to excellent yields of 46-99% using efficient synthesis protocol i.e. sodium metabisulfite catalyzed condensation of aromatic aldehydes with o-phenylenediamines to form 2-arylbenzimidazole derivatives followed by N-alkylation by conventional heating or microwave irradiation for diversification. Potent antibacterial compounds against MSSA and MRSA were discovered such as benzimidazole compounds 3k (2-(4-nitrophenyl), N-benzyl), 3l (2-(4-chlorophenyl), N-(4-chlorobenzyl)), 4c (2-(4-chlorophenyl), 6-methyl, N-benzyl), 4g (2-(4-nitrophenyl), 6-methyl, N-benzyl), and 4j (2-(4-nitrophenyl), 6-methyl, N-(4-chlorobenzyl)) with MIC of 4-16 mu g mL(-1). In addition, compound 4c showed good antimicrobial activities (MIC = 16 mu g mL(-1)) against the bacteria strains Escherichia coli and Streptococcus faecalis. Moreover, compounds 3k, 3l, 4c, 4g, and 4j have been found to kill HepG2, MDA-MB-231, MCF7, RMS, and C26 cancer cells with low mu M IC50 (2.39-10.95). These compounds showed comparable drug-like properties as ciprofloxacin, fluconazole, and paclitaxel in computational ADMET profiling. Finally, docking studies were used to assess potential protein targets responsible for their biological activities. Especially, we found that DHFR is a promising target both in silico and in vitro with compound 4c having IC50 of 2.35 mu M.
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3.
  • Kariippanon, Katharina E., et al. (författare)
  • Levels and Correlates of Objectively Measured Sedentary Behavior in Young Children : SUNRISE Study Results from 19 Countries
  • 2022
  • Ingår i: Medicine & Science in Sports & Exercise. - : Lippincott, Williams & Wilkins. - 0195-9131 .- 1530-0315. ; 54:7, s. 1123-1130
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose There is a paucity of global data on sedentary behavior during early childhood. The purpose of this study was to examine how device-measured sedentary behavior in young children differed across geographically, economically, and sociodemographically diverse populations, in an international sample. Methods This multinational, cross-sectional study included data from 1071 children 3-5 yr old from 19 countries, collected between 2018 and 2020 (pre-COVID). Sedentary behavior was measured for three consecutive days using activPAL accelerometers. Sedentary time, sedentary fragmentation, and seated transport duration were calculated. Linear mixed models were used to examine the differences in sedentary behavior variables between sex, country-level income groups, urban/rural settings, and population density. Results Children spent 56% (7.4 h) of their waking time sedentary. The longest average bout duration was 81.1 +/- 45.4 min, and an average of 61.1 +/- 50.1 min center dot d(-1) was spent in seated transport. Children from upper-middle-income and high-income countries spent a greater proportion of the day sedentary, accrued more sedentary bouts, had shorter breaks between sedentary bouts, and spent significantly more time in seated transport, compared with children from low-income and lower-middle-income countries. Sex and urban/rural residential setting were not associated with any outcomes. Higher population density was associated with several higher sedentary behavior measures. Conclusions These data advance our understanding of young childrens sedentary behavior patterns globally. Country income levels and population density appear to be stronger drivers of the observed differences, than sex or rural/urban residential setting.
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4.
  • Le, Phong Q., et al. (författare)
  • Iodine-promoted amide formation via oxidative cleavage of indoles : novel quinazoline-4(3H)-one and tryptanthrin syntheses
  • 2024
  • Ingår i: RSC Advances. - : Royal Society of Chemistry. - 2046-2069. ; 14:22, s. 15597-15603
  • Tidskriftsartikel (refereegranskat)abstract
    • A highly efficient method for the direct construction of amide bonds via a selective cleavage of C-H and C=C bonds in indole structures using an iodine-promoted approach was developed. Mechanistic studies indicated the formation of superoxide radicals obtained from molecular oxygen activation as a key intermediate step, which provided a precursor for subsequent oxidative ring-opening and intermolecular cyclization. A broad range of quinazolin-4(3H)-ones and tryptanthrins were synthesized in moderate to good yields under mild and environmentally benign conditions.
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5.
  • McCauley, Brian, et al. (författare)
  • Digital gaming culture in Vietnam : an exploratory study
  • 2020
  • Ingår i: Leisure Studies. - : Taylor & Francis. - 0261-4367 .- 1466-4496. ; 39:3, s. 372-386
  • Tidskriftsartikel (refereegranskat)abstract
    • New information and communication technologies continue to spread rapidly into the Asian marketplace, which has led to new patterns of leisure consumption, one of the most popular being digital gaming. However, in Vietnam there is limited research on gaming as a leisure activity. The purpose of this study is to explore the phenomenon of digital gaming in Vietnam to better understand how it is practiced in this culture. Semi-structured interviews were conducted with twenty-five gaming industry figures and gamers. Thematic analysis was used to guide data collection and analysis. The findings indicate that glocalisation, socialised gaming practices and competitiveness characterise the Vietnamese gaming experience. The distinct culture of Vietnam combined with globalised gaming consumption habits has created new modes of play culture, and hence leisure experiences that are growing in pervasive and influential ways.
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6.
  • Okely, Anthony D., et al. (författare)
  • Cross-sectional examination of 24-hour movement behaviours among 3-and 4-year-old children in urban and rural settings in low-income, middle-income and high-income countries : the SUNRISE study protocol
  • 2021
  • Ingår i: BMJ Open. - : BMJ Publishing Group Ltd. - 2044-6055. ; 11:10
  • Tidskriftsartikel (refereegranskat)abstract
    • Introduction 24-hour movement behaviours (physical activity, sedentary behaviour and sleep) during the early years are associated with health and developmental outcomes, prompting the WHO to develop Global guidelines for physical activity, sedentary behaviour and sleep for children under 5 years of age. Prevalence data on 24-hour movement behaviours is lacking, particularly in low-income and middle-income countries (LMICs). This paper describes the development of the SUNRISE International Study of Movement Behaviours in the Early Years protocol, designed to address this gap. Methods and analysis SUNRISE is the first international cross-sectional study that aims to determine the proportion of 3- and 4-year-old children who meet the WHO Global guidelines. The study will assess if proportions differ by gender, urban/rural location and/or socioeconomic status. Executive function, motor skills and adiposity will be assessed and potential correlates of 24-hour movement behaviours examined. Pilot research from 24 countries (14 LMICs) informed the study design and protocol. Data are collected locally by research staff from partnering institutions who are trained throughout the research process. Piloting of all measures to determine protocol acceptability and feasibility was interrupted by COVID-19 but is nearing completion. At the time of publication 41 countries are participating in the SUNRISE study. Ethics and dissemination The SUNRISE protocol has received ethics approved from the University of Wollongong, Australia, and in each country by the applicable ethics committees. Approval is also sought from any relevant government departments or organisations. The results will inform global efforts to prevent childhood obesity and ensure young children reach their health and developmental potential. Findings on the correlates of movement behaviours can guide future interventions to improve the movement behaviours in culturally specific ways. Study findings will be disseminated via publications, conference presentations and may contribute to the development of local guidelines and public health interventions.
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7.
  • Thi Thanh Ngo, Huong, et al. (författare)
  • Prediction of Flash Flood Susceptibility of Hilly Terrain Using Deep Neural Network: A Case Study of Vietnam
  • 2023
  • Ingår i: CMES - Computer Modeling in Engineering & Sciences. - : Tech Science Press. - 1526-1492 .- 1526-1506. ; 135:3, s. 2219-2241
  • Tidskriftsartikel (refereegranskat)abstract
    • Flash floods are one of the most dangerous natural disasters, especially in hilly terrain, causing loss of life, property, and infrastructures and sudden disruption of traffic. These types of floods are mostly associated with landslides and erosion of roads within a short time. Most of Vietnam is hilly and mountainous; thus, the problem due to flash flood is severe and requires systematic studies to correctly identify flood susceptible areas for proper landuse planning and traffic management. In this study, three Machine Learning (ML) methods namely Deep Learning Neural Network (DL), Correlation-based Feature Weighted Naive Bayes (CFWNB), and Adaboost (AB-CFWNB) were used for the development of flash flood susceptibility maps for hilly road section (115 km length) of National Highway (NH)-6 in Hoa Binh province, Vietnam. In the proposed models, 88 past flash flood events were used together with 14 flash floods affecting topographical and geo-environmental factors. The performance of the models was evaluated using standard statistical measures including Receiver Operating Characteristic (ROC) Curve, Area Under Curve (AUC) and Root Mean Square Error (RMSE). The results revealed that all the models performed well (AUC > 0.80) in predicting flash flood susceptibility zones, but the performance of the DL model is the best (AUC: 0.972, RMSE: 0.352). Therefore, the DL model can be applied to develop an accurate flash flood susceptibility map of hilly terrain which can be used for proper planning and designing of the highways and other infrastructure facilities besides landuse management of the area.
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8.
  • Tran, Hang Thi Thanh, et al. (författare)
  • Therapeutic hypothermia after perinatal asphyxia in Vietnam : medium-term outcomes at 18 months - a prospective cohort study
  • 2024
  • Ingår i: BMJ Paediatrics Open. - : BMJ Publishing Group Ltd. - 2399-9772. ; 8:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Aim To determine neurodevelopmental outcome at 18 months after therapeutic hypothermia for hypoxic-ischaemic encephalopathy (HIE) infants in Vietnam, a low-middle-income country. Method Prospective cohort study investigating outcomes at 18 months in severely asphyxiated outborn infants who underwent therapeutic hypothermia for HIE in Hanoi, Vietnam, during the time period 2016-2019. Survivors were examined at discharge and at 6 and 18 months by a neonatologist, a neurologist and a rehabilitation physician, who were blinded to the infants' clinical severity during hospitalisation using two assessment tools: the Ages and Stages Questionnaire (ASQ) and the Hammersmith Infant Neurological Examination (HINE), to detect impairments and promote early interventions for those who require it. Results In total, 130 neonates, 85 (65%) with moderate and 45 (35%) with severe HIE, underwent therapeutic hypothermia treatment using phase change material. Forty-three infants (33%) died during hospitalisation and in infancy. Among the 87 survivors, 69 (79%) completed follow-up until 18 months. Nineteen children developed cerebral palsy (8 diplegia, 3 hemiplegia, 8 dyskinetic), and 11 had delayed neurodevelopment. At each time point, infants with a normal or delayed neurodevelopment had significantly higher ASQ and HINE scores (p<0.05) than those with cerebral palsy. Conclusion The rates of mortality and adverse neurodevelopment rate were high and comparable to recently published data from other low-middle-income settings. The ASQ and HINE were useful tools for screening and evaluation of neurodevelopment and neurological function.
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