| 1. |
- Haglund, Håkan, et al.
(författare)
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Snow Accumulation in Real-time
- 2002
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Ingår i: Proceedings from SIGRAD 2002. ; , s. 11-15
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Konferensbidrag (refereegranskat)abstract
- Whenever real-time snowfall is animated in computer games, no snow accumulation is simulated, as far as we know. Instead, so-called zero thickness is used, which means that the blanket of snow does not grow when the snowflakes reach the ground. In this paper we present a method for simulation of snow accumulation, which simulates the different stages, starting with a snow free environment and ending with a totally snow covered scene, all in real-time. The main focus is not on the physical properties of snow but on speed and visual result.
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| 2. |
- Haglund, Mattias, et al.
(författare)
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Cerebral amyloid angiopathy, white matter lesions and Alzheimer encephalopathy - A histopathological assessment
- 2002
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Ingår i: Dementia and Geriatric Cognitive Disorders. - : S. Karger AG. - 1420-8008 .- 1421-9824. ; 14:3, s. 161-166
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Tidskriftsartikel (refereegranskat)abstract
- To test the hypothesis that the cerebral amyloid angiopathy (CAA) of Alzheimer's disease (AD) is quantitatively associated with white matter lesions (WML), the brains of 63 demented patients exhibiting varying degrees of Alzheimer encephalopathy (AE) were examined, along with those of 10 nondemented control cases. The ratio of amyloid-positive to amyloid-negative vessels in the leptomeninges of the frontal pole from each patient was calculated subsequent to microscopical examination, and the severity of WML was graded according to previously published criteria. In AD cases without a significant component of vascular dementia, the level of CAA was found to correlate with the degree of WML diagnosed and graded by neuropathology. Neither age nor severity of AE correlated significantly with WML. There may be several reasons for the conflicting results of this study vis-a-vis earlier investigations; the roles played by different methods of staining, CAA quantitation and patient subgroup selection are also discussed. Copyright (C)2002 S. Karger AG, Basel.
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| 3. |
- Haglund, Mattias, et al.
(författare)
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Severe Cerebral Amyloid Angiopathy Characterizes an Underestimated Variant of Vascular Dementia.
- 2004
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Ingår i: Dementia and Geriatric Cognitive Disorders. - : S. Karger AG. - 1420-8008 .- 1421-9824. ; 18:2, s. 132-137
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Tidskriftsartikel (refereegranskat)abstract
- Cerebral amyloid angiopathy (CAA) is a frequent finding on neuropathological examination of patients with Alzheimer’s disease (AD). A recent study from our laboratory showed that CAA also frequently occurred in vascular dementia with additional mild Alzheimer encephalopathy (VaD-ae, i.e. Alzheimer pathology that does not fulfill criteria for AD). Because CAA is associated with cerebral hemorrhages and infarctions, it is of significant interest to confirm or dismiss the hypothesis that CAA contributes clinically in the many patients that present with VaD-ae. Therefore, we examined entire temporal lobes of 11 VaD-ae cases and 11 age-matched AD cases with Aβ immunohistochemistry. Six of 11 VaD-ae cases had severe CAA, more extensive than in any AD case. There was a trend toward more cortical infarctions in this group, indicating that CAA in VaD may be of clinical importance and an underestimated cause of dementia.
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