| 1. |
- Ceccato, Vania, et al.
(författare)
-
Assessing the geography of vandalism : Evidence from a Swedish city
- 2005
-
Ingår i: Urban Studies. - : SAGE Publications. - 0042-0980 .- 1360-063X. ; 42:9, s. 1637-1656
-
Tidskriftsartikel (refereegranskat)abstract
- This paper investigates the occurrence of vandalism at the small-area level for the Swedish city of Malmo using data from the Skane Police Authority's database. Demographic, socioeconomic and land use characteristics measured at the small-area level are used as predictors of vandalism with particular interest in the role of collective resources. Standardised vandalism ratios were calculated and mapped using a geographical information system (GIS). Spatial regression models were used to test hypotheses relating to the variation in vandalism rates. Findings show that spatial variation in vandalism is significantly related to social disorganisation risk factors as well as land use factors, but that the physical presence of local leisure associations (a 'collective resource') produces higher vandalism rates.
|
|
| 2. |
- Ceccato, Vania, Professor, 1968-, et al.
(författare)
-
Short and medium term dynamics and their influence on acquisitive crime rates in the transition States of Estonia, Latvia and Lithuania
- 2008
-
Ingår i: Applied Spatial Analysis and Policy. - : Springer. - 1874-463X .- 1874-4621. ; 1, s. 215-244
-
Tidskriftsartikel (refereegranskat)abstract
- The 1990s saw the three Baltic states of Estonia, Latvia and Lithuania change from centrally planned to more market oriented economies with associated societal transformations. Profound changes such as these create uncertainty and social instability that can lead to social problems including increased rates of crime and disorder. We report and comment upon Police recorded crime data that shows numbers of acquisitive and drug related crimes in the three states from 1993 to 2000. However the scale of economic change including the mediating effects of social institutions may vary from place to place within each state. Acquisitive crime is a phenomenon typical of urban or densely populated regions in the Baltic countries. Analysing regional variation in crime rates provides an opportunity to test whether negative socio-economic change impacts on rates for these crimes. Findings show weak evidence of the effect of social change on crime. Spatial statistical techniques and GIS (Geographical Information Systems) underpin the methodology employed.
|
|
| 3. |
- Ceccato, Vania, et al.
(författare)
-
The geography of homicide in Sao Paulo, Brazil
- 2007
-
Ingår i: Environment and planning A. - : SAGE Publications. - 0308-518X .- 1472-3409. ; 39:7, s. 1632-1653
-
Tidskriftsartikel (refereegranskat)abstract
- The authors investigate geographical patterns of homicide in Sao Paulo, Brazil. The geography of crime in developing world cities has been an underresearched area in part because of the lack of good-quality, geocoded offence data. In the case of Sao Paulo the availability of a new digital police dataset has provided the opportunity to improve our understanding of its crime patterns. The authors report the testing of hypotheses about the spatial variation in homicide rates. This variation is explained by poverty, situational conditions determined by differences in land use, and processes that indicate links with the geography of drug markets and the availability of firearms.
|
|
| 4. |
- Ramesh Babu, J., et al.
(författare)
-
Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration
- 2008
-
Ingår i: Journal of Neurochemistry. - : Wiley. - 0022-3042 .- 1471-4159. ; 106:1, s. 107-120
-
Tidskriftsartikel (refereegranskat)abstract
- The signaling adapter p62 plays a coordinating role in mediating phosphorylation and ubiquitin-dependent trafficking of interacting proteins. However, there is little known about the physiologic role of this protein in brain. Here, we report age-dependent constitutive activation of glycogen synthase kinase 3beta, protein kinase B, mitogen-activated protein kinase, and c-Jun-N-terminal kinase in adult p62(-/-) mice resulting in hyperphosphorylated tau, neurofibrillary tangles, and neurodegeneration. Biochemical fractionation of p62(-/-) brain led to recovery of aggregated K63-ubiquitinated tau. Loss of p62 was manifested by increased anxiety, depression, loss of working memory, and reduced serum brain-derived neurotrophic factor levels. Our findings reveal a novel role for p62 as a chaperone that regulates tau solubility thereby preventing tau aggregation. This study provides a clear demonstration of an Alzheimer-like phenotype in a mouse model in the absence of expression of human genes carrying mutations in amyloid-beta protein precursor, presenilin, or tau. Thus, these findings provide new insight into manifestation of sporadic Alzheimer disease and the impact of obesity.
|
|
