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Träfflista för sökning "WFRF:(Hakkarainen A) srt2:(2005-2009)"

Sökning: WFRF:(Hakkarainen A) > (2005-2009)

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1.
  • Hakkarainen, J, et al. (författare)
  • Human and bovine milk oligosaccharides inhibit Neisseria meningitidis pili attachment in vitro.
  • 2005
  • Ingår i: Journal of Nutrition. - 0022-3166 .- 1541-6100. ; 135:10, s. 2445-2448
  • Tidskriftsartikel (refereegranskat)abstract
    • Milk oligosaccharides have been shown to interfere with adhesion of many pathogens to host mucosal surfaces. Characterization of the adhesion mechanisms of the bacteria to host cell surface is needed to develop novel functional food, infant formulas, and anti-infective drugs. Adhesion of Neisseria meningitidis, a human specific pathogen causing meningitis and septicemia, is not completely understood but is mediated by type IV pili. Here, we developed a microtiter well pili binding assay to investigate the binding activities of N. meningitidis isolated type IV pili to different glycoproteins. Pili binding activities to bovine thyroglobulin and human salivary agglutinin but not to chicken ovalbumin were present. Inhibition of these binding activities was demonstrated by fractionated human or bovine milk oligosaccharides. The binding of neisserial pili to bovine thyroglobulin was most effective and was clearly inhibited by human milk neutral or bovine milk acidic oligosaccharides.
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3.
  • Lourdudoss, Sebastian, et al. (författare)
  • Heteroepitaxy and selective epitaxy for discrete and integrated devices
  • 2006
  • Ingår i: 2006 CONFERENCE ON OPTOELECTRONIC AND MICROELECTRONIC MATERIALS & DEVICES. - NEW YORK : IEEE. - 9781424405770 ; , s. 309-311
  • Konferensbidrag (refereegranskat)abstract
    • We present first results on heteroepitaxy of InP on silicon on insulator (SOI). We also demonstrate InP nanopillar fabrication by means of selective epitaxy. Selective epitaxy is also exploited to fabricate advanced photonic integrated devices for Optical Code Division Multiplex Access (OCDMA) networking applications.
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