| 1. |
|
|
| 2. |
|
|
| 3. |
- Bengtsson, Ulrika, et al.
(författare)
-
Aspects of hypertension - a multi-perspective approach on the way towards adherence and self-management
- 2012
-
Ingår i: Fifth Geneva conference on person-centerd medicine.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Hypertension is a long lasting condition for which a poor adherence to therapy becomes a substantial threat to the individual and public health. Major efforts have been made to explore reasons for poor adherence but few successful interventions have been designed. There is a need for effective strategies tailored for the unique needs of persons with hypertension. We set out to explore and describe relevant aspects of hypertension and hypertension treatment, from the perspective of persons with hypertension and health care providers. Focus group interviews were performed with 12 persons with hypertension and 15 health care providers and analysed according to thematic analysis. Persons with hypertension perceived trust, relationship to providers, well-being and prevention of complications as important aspects of hypertension care. Further they sought to understand the interplay between symptoms and variation of blood pressure. The providers emphasised accessibility, clear and consistent counselling, prevention of complications and educational efforts but doubted patients’ ability to be participating partners in care. The study presents aspects that persons with hypertension and health care providers deem important in hypertension self-management. Our findings provide input for future outcome measures and may increase the understanding of hypertension and treatment from a person-centred perspective.
|
|
| 4. |
- Bengtsson, Ulrika, et al.
(författare)
-
Development of a mobile phone self-report system for persons with hypertension: focus group interviews with patients and providers
- 2013
-
Ingår i: Kardiovaskulära Vårmötet 2013.
-
Konferensbidrag (refereegranskat)abstract
- Ulrika Bengtsson, Lena Ring, Inger Hallberg, Karin Kjellgren Background: Hypertension is a risk factor for cardiovascular disease for which poor adherence to therapy becomes a substantial threat to health. Major efforts have been made to explore reasons for poor adherence but few successful interventions have been designed. There is a need for effective strategies tailored for the unique needs of persons with hypertension. We set out to explore and describe relevant aspects of hypertension and hypertension treatment, from the perspective of persons with hypertension and health care providers. Methods: Focus group interviews were performed with 15 persons with hypertension and 12 health care providers and analysed according to thematic analysis. Results: Persons with hypertension perceived trust, relationship to providers, well-being and prevention of complications as important aspects of hypertension care. Further they sought to understand the interplay between symptoms and variation of blood pressure. The providers emphasised accessibility, clear and consistent counselling, prevention of complications and educational efforts but doubted patients’ ability to be participating partners in care. Conclusion: The study presents aspects that persons with hypertension and health care providers deem important in hypertension self-management. Our finding provides input for future outcome measures, such as self-reports, and may serve as a foundation for the development of a self-report system for persons with hypertension. It may further increase the understanding of hypertension and treatment, from a person-centred perspective.
|
|
| 5. |
- Bengtsson, Ulrika, et al.
(författare)
-
Development of a mobile phone self-report system for persons with hypertension: focus group interviews with patients and providers
- 2013
-
Ingår i: HPH 21 st International Conference on Health Promoting Hospitals and Health Services.
-
Konferensbidrag (refereegranskat)abstract
- Introduction: Hypertension is a risk factor for cardiovascular disease for which poor adherence to therapy becomes a substantial threat to health. Major efforts have been made to explore reasons for poor adherence but few successful interventions have been designed. There is a need for effective strategies designed to facilitate an increased understanding for the complexity of hypertension and treatment by strengthening of patient participation as well as patient empowerment. Purpose / Methods: The aim of this study was to explore and describe relevant aspects of hypertension and hypertension treatment, from the perspective of persons with hypertension and health care providers. Focus group interviews were performed with 15 persons with hypertension and 12 health care providers and analysed according to thematic analysis. Results: Persons with hypertension perceived trust, relationship to providers, well-being and prevention of complications as important aspects of hypertension care. Further they sought to understand the interplay between symptoms and variation of blood pressure. The providers emphasised accessibility, clear and consistent counselling, prevention of complications and educational efforts but doubted patients’ ability to be participating partners in care. Conclusion: The study presents aspects that persons with hypertension and health care providers deem important in hypertension management. Our finding provides input for future outcome measures, such as self-reports and may serve as a foundation for the development of a self-report system for persons with hypertension. They may further facilitate patient empowerment by increasing the understanding of hypertension and its’ treatment, from a person-centred perspective.
|
|
| 6. |
- Bosnyak, S., et al.
(författare)
-
Stimulation of angiotensin AT(2) receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats
- 2010
-
Ingår i: British Journal of Pharmacology. - : Wiley. - 0007-1188 .- 1476-5381. ; 159:3, s. 709-716
-
Tidskriftsartikel (refereegranskat)abstract
- Background and purpose: Angiotensin type 2 receptor (AT(2) receptor) stimulation evokes vasodilator effects in vitro and in vivo that oppose the vasoconstrictor effects of angiotensin type 1 receptors (AT(1) receptors). Recently, a novel non-peptide AT(2) receptor agonist, Compound 21, was described, which exhibited high AT(2) receptor selectivity. Experimental approach: Functional cardiovascular effects of the drug candidate Compound 21 were assessed, using mouse isolated aorta and rat mesenteric arteries in vitro and in conscious spontaneously hypertensive rats (SHR). Key results: Compound 21 evoked dose-dependent vasorelaxations in aortic and mesenteric vessels, abolished by the AT(2) receptor antagonist, PD123319. In vivo, Compound 21 administered alone, at doses ranging from 50 to 1000 ng center dot kg-1 center dot min-1 over 4 h did not decrease blood pressure in conscious normotensive Wistar-Kyoto rats or SHR. However, when given in combination with the AT(1) receptor antagonist, candesartan, Compound 21 (300 ng center dot kg-1 center dot min-1) lowered blood pressure in SHR only. Further analysis in separate groups of conscious SHR revealed that, at a sixfold lower dose, Compound 21 (50 ng center dot kg-1 center dot min-1) still evoked a significant depressor response in adult SHR (similar to 30 mmHg) when combined with different doses of candesartan (0.01 or 0.1 mg center dot kg-1). Moreover, the Compound 21-evoked depressor effect was abolished when co-infused (50 mu g center dot kg-1 center dot min-1 for 2 h) with the AT(2) receptor antagonist PD123319. Conclusion and implications: Collectively, our results indicate that acute administration of Compound 21 evoked blood pressure reductions via AT(2) receptor stimulation. Thus Compound 21 can be considered an excellent drug candidate for further study of AT(2) receptor function in cardiovascular disease.
|
|
| 7. |
|
|
| 8. |
|
|
| 9. |
|
|
| 10. |
- Hallberg, Inger, 1956, et al.
(författare)
-
Patientmedverkan i behandling av högt blodtryck med hjälp av mobiltelefon
- 2012
-
Ingår i: Medicinska riksstämman.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Dålig följsamhet gör att patienter inte får avsedd effekt av läkemedel och/eller livsstilsförändringar vid behandling av högt blodtryck. Det innebär stora ekonomiska förluster för samhället samt påverkar den enskilde patientens hälsa och livskvalitet. Studiens syfte var att analysera erfarenheter och effekter av uppföljning av högt blodtryck med hjälp av mobiltelefon samt undersöka om detta leder till ökad följsamhet och delaktighet i behandlingen. I studien ingick 50 patienter (>30 år) med läkemedel för högt blodtryck. Deltagarna utrustades med en blodtrycksmätare och rapporterade dagligen under 2 månader in blodtryck, välmående, fysisk aktivitet och olika symtom via ett program i sin egen mobiltelefon. De värden som rapporterades i mobiltelefonen var framtagna tillsammans med patienter med högt blodtryck, läkare, sjuksköterskor och farmaceuter. Efter inloggning via internet kunde både patient, behandlande läkare och sjuksköterska se inrapporterade värden i en graf. Uppföljning av erfarenheter av rapportering med mobiltelefon gjordes med intervjuer och inspelade samtal med ljud/video från återbesök för högt blodtryck hos läkare/sjuksköterska. Preliminära analyser visar att både personal och patienter upplevde det värdefullt att kunna se relationen mellan livsstil, symtom, läkemedelsintag och blodtryck, t ex att blodtrycket blev lägre de dagar då de var fysiskt aktiva. Patienterna upplevde att de blev mer delaktiga i det uppföljande återbesöket vilket också bekräftades av personalen. Ett tydligt resultat hittills är att patienterna uppskattar att kunna se hur livsstil påverkar blodtrycket. Detta motiverar en förändrad livsstil och därigenom en bättre följsamhet och ökad delaktighet i behandlingen. Modern informationsteknik kan vara ett stöd till bättre hälsa.
|
|
