| 1. |
- Karlsson, Staffan, 1959-, et al.
(författare)
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Antipsychotic medication in relation to national directives in people with dementia in Sweden
- 2017
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Ingår i: Innovation in Aging. - Oxford : Oxford University Press. - 2399-5300. ; 1:S1, s. 348-349
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to explore trends in treatment with antipsychotic medication in Swedish dementia care as reported in the most recent empirical studies on the topic, and to relate these trends to directives and recommendations from national authorities.The study included two scoping review studies and two empirical studies. The scoping studies reviewed published data in electronic databases as well as Swedish recommendations and directives in the field.During the past decade, recommendations have been developed regarding antipsychotic medication in Sweden. These recommendations were generic at first, but have become increasingly specific and restrictive with time. The scoping review showed that treatment with antipsychotic drugs varied between 6% and 38%, and was higher in younger older persons and those with moderate cognitive impairment and living in nursing homes for people with dementia. A trend towards a decrease in antipsychotic use has been seen over the last 15 years. The empirical studies showed that the medication with antipsychotics decreased from 23.4% in 2001 to 11.5% in 2007, for older people in general as well as for older people with dementia. Among older people with dementia, 10% were utilizing antipsychotic medication, with no difference between those cared for at home and those in nursing homes.Directives from Swedish national authorities seem to have had an impact on antipsychotic medication for people with dementia. Treatment with antipsychotic medication has decreased, while other psychotropic medication has increased. National directives may possibly be even more effective, if applied in combination with systematic follow-ups.
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| 2. |
- Karlsson, Staffan, 1959-, et al.
(författare)
-
Antipsychotic medication in relation to national directives in people with dementia in Sweden
- 2017
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Ingår i: Program Abstracts from the 21st International Association of Gerontology and Geriatrics (IAGG) World Congress. - Washington, DC : The Gerontological Society of America. ; , s. 348-349
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Konferensbidrag (refereegranskat)abstract
- The aim of this study was to explore trends in treatment with antipsychotic medication in Swedish dementia care as reported in the most recent empirical studies on the topic, and to relate these trends to directives and recommendations from national authorities.The study included two scoping review studies and two empirical studies. The scoping studies reviewed published data in electronic databases as well as Swedish recommendations and directives in the field.During the past decade, recommendations have been developed regarding antipsychotic medication in Sweden. These recommendations were generic at first, but have become increasingly specific and restrictive with time. The scoping review showed that treatment with antipsychotic drugs varied between 6% and 38%, and was higher in younger older persons and those with moderate cognitive impairment and living in nursing homes for people with dementia. A trend towards a decrease in antipsychotic use has been seen over the last 15 years. The empirical studies showed that the medication with antipsychotics decreased from 23.4% in 2001 to 11.5% in 2007, for older people in general as well as for older people with dementia. Among older people with dementia, 10% were utilizing antipsychotic medication, with no difference between those cared for at home and those in nursing homes.Directives from Swedish national authorities seem to have had an impact on antipsychotic medication for people with dementia. Treatment with antipsychotic medication has decreased, while other psychotropic medication has increased. National directives may possibly be even more effective, if applied in combination with systematic follow-ups.
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| 3. |
- Karlsson, Staffan, 1959-, et al.
(författare)
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Dementia care in eight European countries from the perspective of recipients and their caregivers
- 2015
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Ingår i: Abstract Booklet. ; , s. 318-318
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Konferensbidrag (refereegranskat)abstract
- Objectives: To investigate persons with dementia and their informal caregivers’ views of inter-sectoral information, communication and collaboration throughout the trajectory of dementia care, in eight European countriesMethods: 137 persons with dementia and their informal caregivers participated in focus group interviews. Content analysis generated a tentative model of information, communication and collaboration for people with dementia and their caregivers.Results: The core nding was that information, communication and collaboration were to be focused on the persons with dementia and the informal caregivers. Entering into the trajectory of the disease and its consequences was addressed as an important point of departure. The relation to professional care required establishing a trusting relationship, tailor-made intervention and a single person or organisation to contact. Professional knowledge and commitment, variation in service, and care adapted to needs were important.Conclusion: As focus of care is on the person with dementia and their informal caregivers, a dyadic approach seems most suitable for dementia care. A trusting relationship and a speci c person or organisation to contact seem to be indicators of best practice, as does adaptation to the needs of the person with dementia and their informal caregiver.
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| 4. |
- Karlsson, Staffan, 1959-, et al.
(författare)
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The trends in treatment with antipsychotic medication in relation to national directives in people with dementia : Review in a Swedish context
- 2017
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Ingår i: Capacity, Creativity and Ageing in Clinical Practice. ; , s. 36-36
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Konferensbidrag (refereegranskat)abstract
- Background: Antipsychotic medication has been commonly used in dementia treatment despite various side effects, which differ for different drug generations. As there is no clear evidence for treatment with antipsychotic medication among older people with dementia, may a review of empirical studies and national directives be beneficial.Objectives: The aim of this study was to explore trends in treatment with antipsychotic medication in Swedish dementia care in nursing homes as reported in the most recent empirical studies on the topic, and to relate these trends to directives from the national authorities.Methods: The study included two scoping review studies based on searches of electronic databases as well as the Swedish directives in the field.Findings: During the past decade, directives have been developed for antipsychotic medication in Sweden. These directives were generic at first, but have become increasingly specific and restrictive with time. The scoping review showed that treatment with antipsychotic drugs varied between 6% and 38%, and was higher in younger older persons and in those with moderate cognitive impairment and living in nursing homes for people with dementia. A decreasing trend in antipsychotic use has been seen over the last 15 years.Conclusions: Directives from the authorities in Sweden may have had an impact on treatment with antipsychotic medication for people with dementia. Treatment with antipsychotic medication has decreased, while treatment with combinations of psychotropic medications is common. National directives may possibly be even more effective, if applied in combination with systematic follow-ups.
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| 5. |
- Karlsson, Staffan, 1959-, et al.
(författare)
-
Treatment with antipsychotic medication in relation to national directives in people with dementia in a Swedish context
- 2016
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Ingår i: 26th Alzheimer Europe Conference – Excellence in dementia research and care. ; , s. 52-52
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Konferensbidrag (refereegranskat)abstract
- The aim of this study was to explore trends in treatment with antipsychotic medication in Swedish dementia care as reported in the most recent empirical studies on the topic, and to relate these trends to directives and recommendations from national authorities.The study included two scoping review studies and two empirical studies. The scoping studies reviewed published data in electronic databases as well as Swedish recommendations and directives in the field.During the past decade, recommendations have been developed regarding antipsychotic medication in Sweden. These recommendations were generic at first, but have become increasingly specific and restrictive with time. The scoping review showed that treatment with antipsychotic drugs varied between 6% and 38%, and was higher in younger older persons and those with moderate cognitive impairment and living in nursing homes for people with dementia. A trend towards a decrease in antipsychotic use has been seen over the last 15 years. The empirical studies showed that the medication with antipsychotics decreased from 23.4% in 2001 to 11.5% in 2007, for older people in general as well as for older people with dementia. Among older people with dementia, 10% were utilizing antipsychotic medication, with no difference between those cared for at home and those in nursing homes.Directives from Swedish national authorities seem to have had an impact on antipsychotic medication for people with dementia. Treatment with antipsychotic medication has decreased, while other psychotropic medication has increased. National directives may possibly be even more effective, if applied in combination with systematic follow-ups.
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| 6. |
- Karlsson, Staffan, 1959-, et al.
(författare)
-
Treatment with antipsychotic medication in relation to national directives in people with dementia in a Swedish context
- 2016
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Ingår i: Presented at the 26th Alzheimer Europe Conference: Excellence in dementia research and care, Copenhagen, Denmark, October 31-November 2, 2016. ; , s. 52-52
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Konferensbidrag (refereegranskat)abstract
- Background: The aim of this study was to explore trends in treatment with antipsychotic medication in Swedish dementia care in the most recent empirical studies on the treatment with antipsychotic treatment and relate it to directives and recommendations from national authorities.Methods: The study included; two scoping review studies and two empirical studies. The scoping studies were review of published data in electronic databases as well as Swedish recommendations and directives in the area.Results: The last decade, recommendations were developed regarding antipsychotic medication in Sweden, in the beginning overviewing to be more and more specific and restrictive. The scoping review showed that the treatment with antipsychotic drugs varied between 6%-38%, and was higher in younger older persons and those with moderate cognitive impairment and living in nursing homes for people with dementia. A trend of a decreased treatment with antipsychotics was seen over the last 15 years. The empirical studies showed that the medication with antipsychotics decreased from 23.5 % in 2001 to 12 % in 2007, for older people in general as well as for older people with dementia. In older people with dementia only, 10% were utilizing antipsychotic medication, with no difference between those in ordinary homes compared to those in nursing homes.Conclusions: Directives from Swedish national authorities seems to have had an impact on antipsychotic medication in people with dementia. The treatment with antipsychotic medication decreased, while other psychotropic medication increased. National directives complemented with systematic follow-ups may possibly be even more effective.Conclusion: Treatment with orexin suppressed phagocytosis and degradation of Aβ. Further investigation suggested that the effects of orexin may be mainly on, or mediated through actin. Further investigations concerning the effects of orexin antagonists may be able to offer new methods to arrest the progress of, or possibly treat, AD.
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