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Träfflista för sökning "WFRF:(Hamm A) srt2:(2000-2004)"

Sökning: WFRF:(Hamm A) > (2000-2004)

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1.
  • Hanson, Hans, et al. (författare)
  • Beach nourishment projects, practices, and objectives - a European overview
  • 2002
  • Ingår i: Coastal Engineering. - 0378-3839. ; 47:2, s. 81-111
  • Tidskriftsartikel (refereegranskat)abstract
    • The uses of beach fill in the countries of the European Union are highlighted and discussed with respect to the general situation, project type and objectives, design and evaluation procedures, legal framework, and financial aspects. As expected, significant differences were found among the investigated countries. In general, the study shows that it would be very profitable for south European countries to learn about the Dutch and German practices, particularly regarding the long-term coastal management and the regular monitoring of the coastal morphology. On the other hand, recent Dutch experience has shown that their legal system is a bit rigid, leading sometimes to renourishments that are less necessary to reach the global objective. (C) 2002 Elsevier Science B.V. All rights reserved.
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  • Wikström, Johan, et al. (författare)
  • Gadobenate dimeglumine-enhanced magnetic resonance angiography of the pelvic arteries
  • 2003
  • Ingår i: Investigative Radiology. - : Ovid Technologies (Wolters Kluwer Health). - 0020-9996 .- 1536-0210. ; 38:8, s. 504-515
  • Tidskriftsartikel (refereegranskat)abstract
    • RATIONALE AND OBJECTIVES: To evaluate 4 doses of gadobenate dimeglumine (Gd-BOPTA) for contrast-enhanced magnetic resonance angiography (CE-MRA) of the pelvic arteries and to compare CE-MRA with unenhanced time-of-flight MRA (2D-TOF-MRA). METHODS: A multicenter Phase II dose-finding study was performed in 136 patients with Gd-BOPTA doses of 0.025, 0.05, 0.1, and 0.2 mmol/kg bodyweight. Evaluation of CE-MRA images and comparison with 2D-TOF-MRA images was performed onsite and by 2 blinded offsite reviewers in terms of subjective image quality, number of lesions detected, and confidence in lesion characterization. RESULTS: Significant (P < 0.05) improvements over unenhanced findings were observed for CE-MRA at all dose levels. For reviewer 1 and the onsite investigators, the overall image quality increased up to a dose of 0.1 mmol/kg and then plateaued. For reviewer 2, increased image quality was noted up to a dose of 0.2 mmol/kg. Significant (P < 0.005) increases in diagnostic confidence on CE-MRA versus unenhanced MRA was observed for all dose groups by reviewer 1 and the onsite investigators and for the 0.1 and 0.2 mmol/kg dose groups by reviewer 2. No serious adverse events were recorded that were attributable to the study drug and no trends in laboratory parameters, vital signs, or electrocardiogram recordings were observed. CONCLUSIONS: Gadobenate dimeglumine-enhanced MRA is safe and significantly more effective than unenhanced 2D-TOF-MRA for imaging the pelvic arteries. A dose of 0.1 mmol/kg appears the most appropriate dose for subsequent Phase III clinical evaluation.
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  • Resultat 1-6 av 6

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