| 1. |
- Niemi, MEK, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 2. |
- Kanai, M, et al.
(författare)
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- 2023
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swepub:Mat__t
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| 3. |
- Abbafati, Cristiana, et al.
(författare)
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- 2020
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Tidskriftsartikel (refereegranskat)
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| 4. |
- Poyatos, R., et al.
(författare)
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Global transpiration data from sap flow measurements: the SAPFLUXNET database
- 2021
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Ingår i: Earth System Science Data. - : Copernicus GmbH. - 1866-3508 .- 1866-3516. ; 13:6, s. 2607-2649
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Tidskriftsartikel (refereegranskat)abstract
- Plant transpiration links physiological responses of vegetation to water supply and demand with hydrological, energy, and carbon budgets at the land-atmosphere interface. However, despite being the main land evaporative flux at the global scale, transpiration and its response to environmental drivers are currently not well constrained by observations. Here we introduce the first global compilation of whole-plant transpiration data from sap flow measurements (SAPFLUXNET, https://sapfluxnet.creaf.cat/, last access: 8 June 2021). We harmonized and quality-controlled individual datasets supplied by contributors worldwide in a semi-automatic data workflow implemented in the R programming language. Datasets include sub-daily time series of sap flow and hydrometeorological drivers for one or more growing seasons, as well as metadata on the stand characteristics, plant attributes, and technical details of the measurements. SAPFLUXNET contains 202 globally distributed datasets with sap flow time series for 2714 plants, mostly trees, of 174 species. SAPFLUXNET has a broad bioclimatic coverage, with woodland/shrubland and temperate forest biomes especially well represented (80 % of the datasets). The measurements cover a wide variety of stand structural characteristics and plant sizes. The datasets encompass the period between 1995 and 2018, with 50 % of the datasets being at least 3 years long. Accompanying radiation and vapour pressure deficit data are available for most of the datasets, while on-site soil water content is available for 56 % of the datasets. Many datasets contain data for species that make up 90 % or more of the total stand basal area, allowing the estimation of stand transpiration in diverse ecological settings. SAPFLUXNET adds to existing plant trait datasets, ecosystem flux networks, and remote sensing products to help increase our understanding of plant water use, plant responses to drought, and ecohydrological processes. SAPFLUXNET version 0.1.5 is freely available from the Zenodo repository (https://doi.org/10.5281/zenodo.3971689; Poyatos et al., 2020a). The "sapfluxnetr" R package - designed to access, visualize, and process SAPFLUXNET data - is available from CRAN.
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| 5. |
- Feigin, Valery L., et al.
(författare)
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Global, regional, and national burden of stroke and its risk factors, 1990-2019 : a systematic analysis for the Global Burden of Disease Study 2019
- 2021
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Ingår i: Lancet Neurology. - : Elsevier. - 1474-4422 .- 1474-4465. ; 20:10, s. 795-820
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Tidskriftsartikel (refereegranskat)abstract
- Background Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are important for evidence-based stroke care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national levels. Methods We applied GBD 2019 analytical tools to calculate stroke incidence, prevalence, mortality, disability-adjusted life-years (DALYs), and the population attributable fraction (PAF) of DALYs (with corresponding 95% uncertainty intervals [UIs]) associated with 19 risk factors, for 204 countries and territories from 1990 to 2019. These estimates were provided for ischaemic stroke, intracerebral haemorrhage, subarachnoid haemorrhage, and all strokes combined, and stratified by sex, age group, and World Bank country income level. Findings In 2019, there were 12.2 million (95% UI 11.0-13.6) incident cases of stroke, 101 million (93.2-111) prevalent cases of stroke, 143 million (133-153) DALYs due to stroke, and 6.55 million (6.00-7.02) deaths from stroke. Globally, stroke remained the second-leading cause of death (11.6% [10.8-12.2] of total deaths) and the third-leading cause of death and disability combined (5.7% [5.1-6.2] of total DALYs) in 2019. From 1990 to 2019, the absolute number of incident strokes increased by 70.0% (67.0-73.0), prevalent strokes increased by 85.0% (83.0-88.0), deaths from stroke increased by 43.0% (31.0-55.0), and DALYs due to stroke increased by 32.0% (22.0-42.0). During the same period, age-standardised rates of stroke incidence decreased by 17.0% (15.0-18.0), mortality decreased by 36.0% (31.0-42.0), prevalence decreased by 6.0% (5.0-7.0), and DALYs decreased by 36.0% (31.0-42.0). However, among people younger than 70 years, prevalence rates increased by 22.0% (21.0-24.0) and incidence rates increased by 15.0% (12.0-18.0). In 2019, the age-standardised stroke-related mortality rate was 3.6 (3.5-3.8) times higher in the World Bank low-income group than in the World Bank high-income group, and the age-standardised stroke-related DALY rate was 3.7 (3.5-3.9) times higher in the low-income group than the high-income group. Ischaemic stroke constituted 62.4% of all incident strokes in 2019 (7.63 million [6.57-8.96]), while intracerebral haemorrhage constituted 27.9% (3.41 million [2.97-3.91]) and subarachnoid haemorrhage constituted 9.7% (1.18 million [1.01-1.39]). In 2019, the five leading risk factors for stroke were high systolic blood pressure (contributing to 79.6 million [67.7-90.8] DALYs or 55.5% [48.2-62.0] of total stroke DALYs), high body-mass index (34.9 million [22.3-48.6] DALYs or 24.3% [15.7-33.2]), high fasting plasma glucose (28.9 million [19.8-41.5] DALYs or 20.2% [13.8-29.1]), ambient particulate matter pollution (28.7 million [23.4-33.4] DALYs or 20.1% [16.6-23.0]), and smoking (25.3 million [22.6-28.2] DALYs or 17.6% [16.4-19.0]). Interpretation The annual number of strokes and deaths due to stroke increased substantially from 1990 to 2019, despite substantial reductions in age-standardised rates, particularly among people older than 70 years. The highest age-standardised stroke-related mortality and DALY rates were in the World Bank low-income group. The fastest-growing risk factor for stroke between 1990 and 2019 was high body-mass index. Without urgent implementation of effective primary prevention strategies, the stroke burden will probably continue to grow across the world, particularly in low-income countries.
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| 6. |
- Alexander, Stephen P. H., et al.
(författare)
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The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
- 2023
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Ingår i: BRITISH JOURNAL OF PHARMACOLOGY. - : British pharmacological society. - 0007-1188 .- 1476-5381. ; 180
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Tidskriftsartikel (refereegranskat)abstract
- The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at . G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
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| 7. |
- Christopoulos, Arthur, et al.
(författare)
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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.
- 2021
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Ingår i: British journal of pharmacology. - : Wiley. - 1476-5381 .- 0007-1188. ; 178 Suppl 1
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Forskningsöversikt (refereegranskat)abstract
- The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15538. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
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| 8. |
- Cornell, David H., 1948, et al.
(författare)
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Dating of Guperas Formation rhyolites changes the stratigraphy of the Mesoproterozoic Sinclair Supergroup of Namibia
- 2020
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Ingår i: South African Journal of Geology. - : Geological Society of South Africa. - 1012-0750 .- 1996-8590. ; 123:4, s. 633-648
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Tidskriftsartikel (refereegranskat)abstract
- The volcanosedimentary Guperas Formation contains the youngest volcanic rocks of the Sinclair Supergroup in the Konkiep Terrane of southern Namibia. Precise U-Pb zircon microbeam dating shows that the Guperas Formation as mapped includes felsic volcanic rocks which belong to both the first (1.37 to 1.33 Ga) and the third (1.11 to 1.07 Ga) magmatic cycle of the Sinclair Supergroup. Volcanic rocks of the 'true' Guperas Formation are dated by three samples, with a combined age of 1108 +/- 10 Ma. The sedimentary rocks mapped as Guperas Formation are also distinguished by two different detrital age spectra into the similar to 1 100 Ma true Guperas Formation and the Aruab Member of the similar to 1 217 Ma Barby Formation. Geochronology now resolves the previous stratigraphic separation of the very similar Nubib and Rooiberg (Sonntag) Granites. The two small outcrops of 1 334 +/- 5 Ma Rooiberg Granite are now shown to be part of the regional 1 334 +/- 8 Ma Nubib Granite batholith. The Konkiep Terrane was affected by faulting and shear zones, but was only gently folded and not involved in regional metamorphism, despite its proximity to the Namaqua-Natal Province to the southwest. This is due to the Konkiep Terrane having a thick and strong continental basement which may have formed as part of the mainly Palaeoproterozoic Rehoboth Province. IIowever no Palaeoproterozoic rocks are exposed in the Konkiep Terrane, which is now interpreted as an unaffiliated terrane. The three cycles of extrusive and plutonic magmatism in the Sinclair Supergroup formed in chronologically distinct periods and different tectonic settings, which requires revision of the stratigraphic nomenclature. The Konkiep Group is replaced by three new groups which are separated by >100 million-year unconformities. The Betta Group, represented by the mainly volcanic Kumbis, Nagatis and Welverdiend formations in the first magmatic cycle, probably formed in a passive continental rift setting due to breakup of the Rehoboth Province between 1 374 and 1 334 Ma. The Vergenoeg Group, represented by the sedimentary Kunjas and volcanic Barby and Haiber Flats formations, formed in a subduction setting at the margin of the Konkiep Terrane. This similar to 1 217 to 1204 Ma magmatic cycle ended with the accretion of Namaqua-Natal terranes to the Kalahari Craton. The similar to 1 100 Ma Ganaams Group, represented by the volcanic Guperas Formation and sedimentary Aubures Formation, was the result of interplay between the continentalscale Umkondo mantle heating event and movements between crustal blocks following the Namaqua-Natal collisional orogeny.
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| 9. |
- Harris, M., et al.
(författare)
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Chronostratigraphic correlation of the volcanic 1.21 Ga Barby and Haiber Flats Formations in the Sinclair Supergroup of Namibia
- 2021
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Ingår i: Journal of African Earth Sciences. - : Elsevier BV. - 1464-343X. ; 178
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Tidskriftsartikel (refereegranskat)abstract
- This work investigates Mesoproterozoic volcanic rocks of the Haiber Flats, Barby, Welverdiend and Kairab Formations, and associated intrusive rocks in the Konkiep Terrane. Various correlations have been made in the past and recent dating work yields contrasting ages. U–Pb dating of zircons is applied in combination with Sm–Nd and Lu–Hf isotopes to determine the age, assess correlation and ascertain the much-debated tectonic setting. Ion probe U–Pb zircon dating yields ages of 1218 ± 5 Ma, 1212 ± 4 Ma and 1212 ± 5 Ma (all errors 2σ) for three samples of the Haiber Flats Formation and 1219 ± 13 Ma, 1215 ± 19 Ma for the Barby Formation. The ages obtained for the Barby Formation agree with the 1217 ± 2 Ma and 1214 ± 5 Ma ages reported from previous investigations. Rocks mapped as the supposedly older Kairab rhyolite and felsic tuff gave younger ages of 1220 ± 4 Ma and 1222 ± 10 Ma, respectively, which are coeval with the Barby and Haiber Flats Formations. Two Gorab Gabbro samples, previously mapped as Kairab Formation, yield ages of 1341 ± 8 Ma and 1336 ± 8 Ma. These older ages are within error of two Welverdiend Formation samples which gave ages of 1344 ± 6 Ma and 1337 ± 9 Ma, and the formation was previously dated in the type area at 1327 ± 10 Ma. These ages confirm the reassignment of rocks originally mapped as tholeiitic Barby Formation into the Welverdiend Formation, north of a newly identified stratigraphic hiatus corresponding to the geophysically defined Wêreldend Lineament. Sm–Nd and Lu–Hf isotopic signatures for the Barby, Haiber Flats and coeval Kairab samples indicate that they are co-magmatic and derived from partly depleted mantle contaminated by older crust. TDM model ages of these samples range from 2.5 to 1.5 Ga with a major 2.2 to 1.8 Ga group. This suggests that the older crustal component was Paleoproterozoic but included some Archean material. The Welverdiend Formation and Gorab Gabbros show similarity in age, Sm–Nd and Lu–Hf characteristics and were probably derived from partially depleted mantle, or from a well-homogenised mixture of depleted mantle and older crust. REE diagrams indicate enrichment in LREE (La–Gd) and a flat HREE pattern (Tb to Lu). On spidergrams, most samples are characterised by negative Nb–Ta anomalies and positive K and Pb anomalies which indicate a subduction-related setting (with positive Sr anomaly) or a reworked crustal origin. The similarity in ages, isotopic signatures and geochemistry confirms the correlation of the Barby and Haiber Flats Formation. © 2021 Elsevier Ltd
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