| 1. |
- Noterdaeme, J. M., et al.
(författare)
-
Heating, current drive and energetic particle studies on JET in preparation of ITER operation
- 2003
-
Ingår i: Nuclear Fusion. - : IOP Publishing. - 0029-5515 .- 1741-4326. ; 43:3, s. 202-209
-
Tidskriftsartikel (refereegranskat)abstract
- This paper summarizes the recent work on JET in the three areas of heating, current drive and energetic particles. The achievements have extended the possibilities of JET, have a direct connection to ITER operation and provide new and interesting physics. Toroidal rotation profiles of plasmas heated far off axis with little or no refuelling or momentum input are hollow with only small differences on whether the power deposition is located on the low field side or on the high field side. With LH current drive the magnetic shear was varied from slightly positive to negative. The improved coupling (through the use of plasma shaping and CD4) allowed up to 3.4 MW of PLH in internal transport barrier (ITB) plasmas with more than 15 MW of combined NBI and ICRF heating. The q-profile with negative magnetic shear and the ITB could be maintained for the duration of the high heating pulse (8 s). Fast ions have been produced in JET with ICRF to simulate alpha particles: by using third harmonic He-4 heating, beam injected He-4 at 120 kV were accelerated to energies above 2 MeV taking advantage of the unique capability of JET to use NBI with 4 He and to confine MeV class ions. ICRF heating was used to replicate the dynamics of alpha heating and the control of an equivalent Q = 10 `burn' was simulated.
|
|
| 2. |
- Heisel, B, et al.
(författare)
-
mu SR-Experiments on proton-conducting oxides
- 2000
-
Ingår i: PHYSICA B. - : ELSEVIER SCIENCE BV. - 0921-4526. ; 289, s. 487-490
-
Tidskriftsartikel (refereegranskat)abstract
- Positive muons implanted in proton-conducting oxides can be used to gain insight into the diffusion and trapping behaviour of light particles in these materials which are used as solid oxide electrolytes in high-temperature fuel cells. We have studied bot
|
|
| 3. |
- Kalvius, GM, et al.
(författare)
-
High pressure mu SR studies: rare earths and related materials
- 2000
-
Ingår i: HYPERFINE INTERACTIONS. - : BALTZER SCI PUBL BV. - 0304-3843. ; 128:1-3, s. 275-303
-
Tidskriftsartikel (refereegranskat)abstract
- After a short introduction to mu SR with respect to the study of magnetic properties, followed by a brief outline of the principle of the high pressure-low temperature mu SR spectrometer installed at the Paul Scherrer Institute, we discuss some measuremen
|
|
| 4. |
- Martin, EM, et al.
(författare)
-
Magnetic properties of GdMn2 from mu SR
- 2000
-
Ingår i: PHYSICA B. - : ELSEVIER SCIENCE BV. - 0921-4526. ; 289, s. 265-268
-
Tidskriftsartikel (refereegranskat)abstract
- GdMn2 has a Neel transition around 100 K and a second magnetic transition near 40 K, which is considered a Curie point. The mu SR data show that both the Gd and the Mn sublattice order at T-N, in contrast to a published model. Using the signal from muons
|
|
| 5. |
- Murin, YA, et al.
(författare)
-
A scintillator based time-of-flight hodoscope with a new type of emitter follower divider
- 2004
-
Ingår i: Nuclear Instruments & Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. - : Elsevier BV. - 0167-5087 .- 0168-9002. ; 533:3, s. 361-369
-
Tidskriftsartikel (refereegranskat)abstract
- A high precision, time-of-flight hodoscope has been constructed to analyse the secondary pion beam at GSI, Darmstadt. The hodoscope comprises three scintillator planes with the individual scintillator rods read out by photomultipliers in both ends. A new active base of the emitter follower type has been developed for stabilization of voltages at the last dynodes of the photomultiplier. The time resolution of this system was found to be sigma less than or equal to 150 ps for counting rates up to 2 MHz.
|
|
| 6. |
|
|
| 7. |
|
|
| 8. |
|
|
| 9. |
- Fellström, Bengt, et al.
(författare)
-
Effect of fluvastatin on renal end points in the Assessment of Lescol in Renal Transplant (ALERT) trial
- 2004
-
Ingår i: Kidney International. - : Elsevier BV. - 0085-2538 .- 1523-1755. ; 66:4, s. 1549-1555
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Hyperlipidemia is a risk factor for long-term renal transplant dysfunction, but no prospective clinical trials have investigated the effects of statin treatment on graft function in renal transplant recipients. The aim of the present study was to evaluate the effect of fluvastatin on long-term renal transplant function and development of chronic allograft nephropathy in the ALERT (Assessment of Lescol in Renal Transplantation) study. METHODS: ALERT was a randomized, double-blind, placebo-controlled study of the effect of fluvastatin, 40 mg and 80 mg daily, in renal transplant recipients. Patients were randomized to receive either fluvastatin (N= 1050) or placebo (N= 1052) and followed for five to six years. Renal end points included graft loss or doubling of serum creatinine or death; glomerular filtration rate (GFR) was also measured during follow-up in a subset of patients (N= 439). RESULTS: There were 283 patients (13.5%) with graft loss, mainly due to chronic rejection (82%), yielding an annual rate of 2.4%. Fluvastatin treatment significantly lowered mean low-density lipoprotein (LDL)-cholesterol levels by 32% (95% CI -33 to -30) compared with placebo, but had no significant effect on the incidence of renal graft loss or doubling of serum creatinine, or decline in GFR throughout follow-up in the whole study population. Neither was any treatment effect by fluvastatin found in any of the subgroups analyzed. CONCLUSION: Fluvastatin treatment significantly improves lipid values in renal transplant recipients but has no effect on graft loss or doubling of serum creatinine.
|
|
| 10. |
- Holdaas, H., et al.
(författare)
-
Effect of fluvastatin on cardiac outcomes in renal transplant recipients : A multicentre, randomised, placebo-controlled trial
- 2003
-
Ingår i: The Lancet. - 0140-6736 .- 1474-547X. ; 361:9374, s. 2024-2031
-
Tidskriftsartikel (refereegranskat)abstract
- Background: Renal transplant recipients are at increased risk of premature cardiovascular disease. Although statins reduce cardiovascular risk in the general population, their efficacy and safety in renal transplant recipients have not been established. We investigated the effects of fluvastatin on cardiac and renal endpoints in this population. Methods: We did a multicentre, randomised, double-blind, placebo-controlled trial in 2102 renal transplant recipients with total cholesterol 4·0-9·0 mmol/L. We randomly assigned patients fluvastatin (n=1050) or placebo (n=1052) and follow up was for 5-6 years. The primary endpoint was the occurrence of a major adverse cardiac event, defined as cardiac death, non-fatal myocardial infarction (MI), or coronary intervention procedure. Secondary endpoints were individual cardiac events, combined cardiac death or non-fatal MI, cerebrovascular events, non-cardiovascular death, all-cause mortality, and graft loss or doubling of serum creatinine. Analysis was by intention to treat. Findings: After a mean follow-up of 5·1 years, fluvastatin lowered LDL cholesterol concentrations by 32%. Risk reduction with fluvastatin for the primary endpoint (risk ratio 0·83 [95% CI 0·64-1·06], p=0·139) was not significant, although there were fewer cardiac deaths or non-fatal MI (70 vs 104, 0·65 [0·48-0·88] p=0·005) in the fluvastatin group than in the placebo group. Coronary intervention procedures and other secondary endpoints did not differ significantly between groups. Interpretation: Although cardiac deaths and non-fatal MI seemed to be reduced, fluvastatin did not generally reduce rates of coronary intervention procedures or mortality. Overall effects of fluvastatin were similar to those of statins in other populations.
|
|
