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Träfflista för sökning "WFRF:(Hartz S. M.) srt2:(2015-2019)"

Sökning: WFRF:(Hartz S. M.) > (2015-2019)

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Numrering	Referens	Omslagsbild	Hitta
1.	Abe, K., et al. (författare) J-PARC Neutrino Beamline Upgrade Technical Design Report 2019 Rapport (refereegranskat)abstract In this document, technical details of the upgrade plan of the J-PARC neutrino beamline for the extension of the T2K experiment are described. T2K has proposed to accumulate data corresponding to 2×1022 protons-on-target in the next decade, aiming at an initial observation of CP violation with 3σ or higher significance in the case of maximal CP violation. Methods to increase the neutrino beam intensity, which are necessary to achieve the proposed data increase, are described.
2.	Polimanti, R, et al. (författare) Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium 2019 Ingår i: Psychological medicine. - 1469-8978. ; 49:7, s. 1218-1226 Tidskriftsartikel (refereegranskat)
3.	Walters, RK, et al. (författare) Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders 2018 Ingår i: Nature neuroscience. - : Springer Science and Business Media LLC. - 1546-1726 .- 1097-6256. ; 21:12, s. 1656- Tidskriftsartikel (refereegranskat)
4.	Hartz, B, et al. (författare) THE MINIMUM REQUIRED LEVEL OF DONOR CHIMERISM IN HEREDITARY HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS - A RETROSPECTIVE STUDY WITH 103 PATIENTS 2015 Ingår i: PEDIATRIC BLOOD & CANCER. - 1545-5009. ; 62, s. S127-S128 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
5.	Johansson, E, et al. (författare) Cost effectiveness of ixekizumab versus secukinumab in the treatment of moderate-to-severe plaque psoriasis in Spain 2018 Ingår i: ClinicoEconomics and outcomes research : CEOR. - 1178-6981. ; 10, s. 747-759 Tidskriftsartikel (refereegranskat)
6.	Strawbridge, RJ, et al. (författare) Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort 2018 Ingår i: Translational psychiatry. - : Springer Science and Business Media LLC. - 2158-3188. ; 8:1, s. 39- Tidskriftsartikel (refereegranskat)abstract Risk-taking behaviour is a key component of several psychiatric disorders and could influence lifestyle choices such as smoking, alcohol use, and diet. As a phenotype, risk-taking behaviour therefore fits within a Research Domain Criteria (RDoC) approach, whereby identifying genetic determinants of this trait has the potential to improve our understanding across different psychiatric disorders. Here we report a genome-wide association study in 116,255 UK Biobank participants who responded yes/no to the question “Would you consider yourself a risk taker?” Risk takers (compared with controls) were more likely to be men, smokers, and have a history of psychiatric disorder. Genetic loci associated with risk-taking behaviour were identified on chromosomes 3 (rs13084531) and 6 (rs9379971). The effects of both lead SNPs were comparable between men and women. The chromosome 3 locus highlights CADM2, previously implicated in cognitive and executive functions, but the chromosome 6 locus is challenging to interpret due to the complexity of the HLA region. Risk-taking behaviour shared significant genetic risk with schizophrenia, bipolar disorder, attention-deficit hyperactivity disorder, and post-traumatic stress disorder, as well as with smoking and total obesity. Despite being based on only a single question, this study furthers our understanding of the biology of risk-taking behaviour, a trait that has a major impact on a range of common physical and mental health disorders.

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Typ av publikation: tidskriftsartikel (4); rapport (1); konferensbidrag (1)

Typ av innehåll: refereegranskat (5); övrigt vetenskapligt/konstnärligt (1)

Författare/redaktör: Mbarek, H (2); Gordon, S (2); Hottenga, JJ (2); Magnusson, P (2); Rose, R (2); Palviainen, T (2); visa fler...; Meyers, JL (2); Agrawal, A (2); Degenhardt, L (2); Thomas, N (2); Boomsma, DI (2); Sanchez-Roige, S (2); Fontanillas, P (2); Pedersen, NL (2); Palmer, AA (2); Penninx, BWJH (2); Rujescu, D (2); Adkins, DE (2); Webb, BT (2); Choi, DS (2); Hoffmann, P (2); Milaneschi, Y (2); Cichon, S (2); Foroud, TM (2); McIntosh, AM (2); Montgomery, GW (2); Muller-Myhsok, B (2); Nothen, MM (2); Rietschel, M (2); Martin, NG (2); Medland, SE (2); Adams, MJ (2); Lucae, S (2); Copeland, WE (2); Silberg, J (2); Costello, EJ (2); Degenhardt, F (2); Chen, LS (2); Lichtenstein, P. (2); Lahti, J (2); Raikkonen, K. (2); Palotie, A (2); Dahmen, N (2); Neale, BM (2); Mannisto, S (2); Eriksson, JG (2); Ripatti, S (2); Herms, S. (2); Hartz, S (2); Streit, F (2); visa färre...

Lärosäte: Karolinska Institutet (5); Linköpings universitet (1)

Språk: Engelska (6)

Forskningsämne (UKÄ/SCB): Naturvetenskap (1); Medicin och hälsovetenskap (1)

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