| 1. |
- Anwar, Hassan, et al.
(författare)
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Exploring Spiking Neural Network on Coarse-Grain Reconfigurable Architectures
- 2014
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Ingår i: ACM International Conference Proceeding Series. - New York, NY, USA : ACM. - 9781450328227 ; , s. 64-67
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Konferensbidrag (refereegranskat)abstract
- Today, reconfigurable architectures are becoming increas- ingly popular as the candidate platforms for neural net- works. Existing works, that map neural networks on re- configurable architectures, only address either FPGAs or Networks-on-chip, without any reference to the Coarse-Grain Reconfigurable Architectures (CGRAs). In this paper we investigate the overheads imposed by implementing spiking neural networks on a Coarse Grained Reconfigurable Ar- chitecture (CGRAs). Experimental results (using point to point connectivity) reveal that up to 1000 neurons can be connected, with an average response time of 4.4 msec.
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| 2. |
- Khalil, Eltahir A G, et al.
(författare)
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Safety and efficacy of single dose versus multiple doses of AmBisome for treatment of visceral leishmaniasis in eastern Africa : a randomised trial.
- 2014
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Ingår i: PLoS Neglected Tropical Diseases. - : Public Library of Science (PLoS). - 1935-2727 .- 1935-2735. ; 8:1, s. e2613-
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Anti-leishmanial drug regimens that include a single dose AmBisome could be suitable for eastern African patients with symptomatic visceral leishmaniasis (VL) but the appropriate single dose is unknown.METHODOLOGY: A multi-centre, open-label, non-inferiority, randomized controlled trial with an adaptive design, was conducted to compare the efficacy and safety of a single dose and multiple doses of AmBisome for the treatment of VL in eastern Africa. The primary efficacy endpoint was definitive cure (DC) at 6 months. Symptomatic patients with parasitologically-confirmed, non-severe VL, received a single dose of AmBisome 7.5 mg/kg body weight or multiple doses, 7 times 3 mg/kg on days 1-5, 14, and 21. If interim analyses, evaluated 30 days after the start of treatment following 40 or 80 patients, showed the single dose gave significantly poorer parasite clearance than multiple doses at the 5% significance level, the single dose was increased by 2·5 mg/kg. In a sub-set of patients, parasite clearance was measured by quantitative reverse transcriptase (qRT) PCR.PRINCIPAL FINDINGS: The trial was terminated after the third interim analysis because of low efficacy of both regimens. Based on the intention-to-treat population, DC was 85% (95%CI 73-93%), 40% (95%CI 19-64%), and 58% (95%CI 41-73%) in patients treated with multiple doses (n = 63), and single doses of 7·5 (n = 21) or 10 mg/kg (n = 40), respectively. qRT-PCR suggested superior parasite clearance with multiple doses as early as day 3. Safety data accorded with the drug label.CONCLUSIONS: The tested AmBisome regimens would not be suitable for VL treatment across eastern Africa. An optimal single dose regimen was not identified.TRIALS REGISTRATION: www.clinicaltrials.govNCT00832208.
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| 3. |
- Ahmed, Abubeker W., et al.
(författare)
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An Algorithm to Estimate Rational Values of Phase Angles and Moduli of Asphalt Mixtures
- 2013
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Ingår i: International Journal of Pavement Research and Technology. - Taiwan : Chinese Society of Pavement Engineering. - 1996-6814 .- 1997-1400. ; 6:6, s. 745-754
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Tidskriftsartikel (refereegranskat)abstract
- The objective of this study was to develop and evaluate an algorithm based on Fast Fourier Transform (FFT) that can calculate rational values of phase angle (f) and moduli of the variants of asphalt mixtures for the data obtained from the different frequency sweep tests. f and moduli for ten different asphalt mixtures resulting in over 690 data points collected from both USA and Sweden were computed using FFT. Theoretical observations revealed that there were significant differences for f between FFT and other methods to the order of 10-50%; however, there was no difference in moduli estimates for any mix and was independent of the test. Precisely, the FFT method produced rational f for mixtures that deviate from conventional mixture properties. Furthermore, statistical comparisons corroborated the predicted f estimates indicative of significant differences between the analysis techniques; but, the moduli were unaffected by the analysis methods. The study successfully illustrated the FFT technique, a user-friendly analytical procedure that can obviate the errors in the rational estimation of the acutely sensitive viscoelastic parameters.
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| 4. |
- Farahini, Nasim, et al.
(författare)
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Parallel distributed scalable runtime address generation scheme for a coarse grain reconfigurable computation and storage fabric
- 2014
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Ingår i: Microprocessors and microsystems. - : Elsevier BV. - 0141-9331 .- 1872-9436. ; 38:8, s. 788-802
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents a hardware based solution for a scalable runtime address generation scheme for DSP applications mapped to a parallel distributed coarse grain reconfigurable computation and storage fabric. The scheme can also deal with non-affine functions of multiple variables that typically correspond to multiple nested loops. The key innovation is the judicious use of two categories of address generation resources. The first category of resource is the low cost AGU that generates addresses for given address bounds for affine functions of up to two variables. Such low cost AGUs are distributed and associated with every read/write port in the distributed memory architecture. The second category of resource is relatively more complex but is also distributed but shared among a few storage units and is capable of handling more complex address generation requirements like dynamic computation of address bounds that are then used to configure the AGUs, transformation of non-affine functions to affine function by computing the affine factor outside the loop, etc. The runtime computation of the address constraints results in negligibly small overhead in latency, area and energy while it provides substantial reduction in program storage, reconfiguration agility and energy compared to the prevalent pre-computation of address constraints. The efficacy of the proposed method has been validated against the prevalent address generation schemes for a set of six realistic DSP functions. Compared to the pre-computation method, the proposed solution achieved 75% average code compaction and compared to the centralized runtime address generation scheme, the proposed solution achieved 32.7% average performance improvement.
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| 5. |
- Hamid Muhammed, Hamed, 1967-, et al.
(författare)
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Skin Cancer Detection Using Temperature Variation Analysis
- 2013
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Ingår i: Engineering. - 1947-394X. ; 5:10B
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Tidskriftsartikel (refereegranskat)abstract
- In the medical field, new technologies are incorporated for the sole purpose of enhancing the quality of life for the patients and even for the normal healthy people. Infrared technology is one of the technologies that have some applications in both the medical and biological fields. In this work, the thermal infrared (IR) measurement is used to investigate the potential of skin cancer detection. IR enjoys non-invasive and non-contact advantages as well as favorable cost, apparently. It is also very well developed regarding the technological and methodological aspects. IR per se is an electro-metric radiation that all objects emit when their temperature is above the absolute zero. And the human body is not different in this regard. The IR range extends, ideally, to cover wavelengths from 800 nanometer to few hundred micrometer. Cancer, in modern life, has grown tangibly due to many factors, such as life expectancies increase, personal habits and ultraviolet radiation exposures among others. Moreover, the significant enhancement of technologies has helped identifying more types of cancers than before. The sole purpose of this work is to investigate further IR technology methods and applications not yet matured in skin cancer detection to enhance the detection ability with higher safety level.
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| 6. |
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| 7. |
- Hassan, Osama Ahmed, et al.
(författare)
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A need for One Health approach : lessons learned from outbreaks of Rift Valley fever in Saudi Arabia and Sudan
- 2014
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Ingår i: Infection Ecology & Epidemiology. - : CoAction Publishing. - 2000-8686. ; 4
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Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: Rift Valley fever (RVF) is an emerging viral zoonosis that impacts human and animal health. It is transmitted from animals to humans directly through exposure to blood, body fluids, or tissues of infected animals or via mosquito bites. The disease is endemic to Africa but has recently spread to Saudi Arabia and Yemen. Our aim was to compare two major outbreaks of RVF in Saudi Arabia (2000) and Sudan (2007) from a One Health perspective.METHODS: Using the terms 'Saudi Arabia', 'Sudan', and 'RVF', articles were identified by searching PubMed, Google Scholar, and web pages of international organizations as well as local sources in Saudi Arabia and Sudan.RESULTS: The outbreak in Saudi Arabia caused 883 human cases, with a case fatality rate of 14% and more than 40,000 dead sheep and goats. In Sudan, 698 human cases of RVF were recognized (case fatality, 31.5%), but no records of affected animals were available. The ecology and environment of the affected areas were similar with irrigation canals and excessive rains providing an attractive habitat for mosquito vectors to multiply. The outbreaks resulted in livestock trade bans leading to a vast economic impact on the animal market in the two countries. The surveillance system in Sudan showed a lack of data management and communication between the regional and federal health authorities, while in Saudi Arabia which is the stronger economy, better capacity and contingency plans resulted in efficient countermeasures. Studies of the epidemiology and vectors were also performed in Saudi Arabia, while in Sudan these issues were only partly studied.CONCLUSION: We conclude that a One Health approach is the best option to mitigate outbreaks of RVF. Collaboration between veterinary, health, and environmental authorities both on national and regional levels is needed.
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| 8. |
- Hassan, Osama Ahmed, et al.
(författare)
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The 2007 rift valley Fever outbreak in Sudan
- 2011
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Ingår i: PLoS Neglected Tropical Diseases. - San Francisco, CA : Public Library of Science. - 1935-2727 .- 1935-2735. ; 5:9
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Forskningsöversikt (refereegranskat)abstract
- Rift Valley fever (RVF) is a neglected, emerging, mosquito-borne disease with severe negative impact on human and animal health and economy. RVF is caused by RVF virus (RVFV) affecting humans and a wide range of animals. The virus is transmitted through bites from mosquitoes and exposure to viremic blood, body fluids, or tissues of infected animals. During 2007 a large RVF outbreak occurred in Sudan with a total of 747 confirmed human cases including 230 deaths (case fatality 30.8%); although it has been estimated 75,000 were infected. It was most severe in White Nile, El Gezira, and Sennar states near to the White Nile and the Blue Nile Rivers. Notably, RVF was not demonstrated in livestock until after the human cases appeared and unfortunately, there are no records or reports of the number of affected animals or deaths. Ideally, animals should serve as sentinels to prevent loss of human life, but the situation here was reversed. Animal contact seemed to be the most dominant risk factor followed by animal products and mosquito bites. The Sudan outbreak followed an unusually heavy rainfall in the country with severe flooding and previous studies on RVF in Sudan suggest that RVFV is endemic in parts of Sudan. An RVF outbreak results in human disease, but also large economic loss with an impact beyond the immediate influence on the directly affected agricultural producers. The outbreak emphasizes the need for collaboration between veterinary and health authorities, entomologists, environmental specialists, and biologists, as the best strategy towards the prevention and control of RVF.
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| 9. |
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| 10. |
- Jafri, Syed Mohammad Asad Hassan, et al.
(författare)
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Compression Based Efficient and Agile Configuration Mechanism for Coarse Grained Reconfigurable Architectures
- 2011
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Ingår i: Proc. IEEE Int Parallel and Distributed Processing Workshops and Phd Forum (IPDPSW) Symp. - 9780769543857 ; , s. 290-293
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Konferensbidrag (refereegranskat)abstract
- This paper considers the possibility of speeding up the configuration by reducing the size of configware in coarsegrained reconfigurable architectures (CGRAs). Our goal was to reduce the number of cycles and increase the configuration bandwidth. The proposed technique relies on multicasting and bitstream compression. The multicasting reduces the cycles by configuring the components performing identical functions simultaneously, in a single cycle, while the bitstream compression increases the configuration bandwidth. We have chosen the dynamically reconfigurable resource array (DRRA) architecture as a vehicle to study the efficiency of this approach. In our proposed method, the configuration bitstream is compressed offline and stored in a memory. If reconfiguration is required, the compressed bitstream is decompressed using an online decompresser and sent to DRRA. Simulation results using practical applications showed upto 78% and 22% decrease in configuration cycles for completely parallel and completely serial implementations, respectively. Synthesis results have confirmed nigligible overhead in terms of area (1.2 %) and timing.
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