| 2. |
- Heiberg, Einar, et al.
(författare)
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Time resolved three-dimensional automated segmentation of the left ventricle
- 2005
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Ingår i: Computers in Cardiology 2005. - 0780393376 ; 32, s. 599-602
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Konferensbidrag (refereegranskat)abstract
- This paper describes a robust approach for multimodality segmentation of the cardiac left ventricle. The method is based on the concept of deformable models, but extended with an enhanced and fast edge detection scheme that includes temporal information, and anatomical a priori information. The algorithm is implemented with a fast numeric scheme for solving energy minimization, and efficient filter nets for fast edge detection. This allows clinically applicable time for a whole time resolved 3D cardiac data set to be achieved on a standard desktop computer. The algorithm is validated on images acquired using MRI gradient echo, MRI (SSFP) images, and Cardiac CT The complete algorithm is implemented into a software package freely available for non commercial research at http://segment.heiberg.se
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| 3. |
- Malm, Gunilla, et al.
(författare)
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Mucopolysaccharidoses in the Scandinavian countries: incidence and prevalence.
- 2008
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Ingår i: Acta paediatrica (Oslo, Norway : 1992). - : Wiley. - 1651-2227 .- 0803-5253. ; 97:11, s. 1577-81
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Tidskriftsartikel (refereegranskat)abstract
- AIM: The aim of this study was to estimate the incidence and prevalence of mucopolysaccharidoses (MPS disorders) in Scandinavia. METHODS: The retrospective period used for the incidence study covered the period from 1975 to 2004 in Sweden and Denmark and from 1979 to 2004 in Norway. Prevalence was derived from the number of MPS patients alive as of December 31, 2007. RESULTS: The incidence of all MPS disorders was 1.75 cases in Sweden, 3.08 cases in Norway and 1.77 cases in Denmark per 100 000 newborns. The incidence of MPS I was the most common in all three countries, with 0.67, 1.85 and 0.54 cases per 100 000 newborns, respectively; for MPS II, numbers were 0.27, 0.13 and 0.27, respectively. For patients with other MPS disorders the incidence varied widely. The prevalence for all MPS disorders was 4.24, 7.06 and 6.03 per 1 000 000 inhabitants in Sweden, Norway and Denmark, respectively. CONCLUSION: From three Scandinavian countries the incidence of MPS disorders is retrospectively evaluated for 25 years in Norway and 30 years in Sweden and Denmark. Incidence and prevalence studies of lysosomal disorders are prerequisites for cost benefit calculations in the face of newly developed and expensive therapies in the future.
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