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- Johansen, K. R., et al.
(författare)
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Risk of atrial fibrillation and stroke among older men exposed to prolonged endurance sport practice: a 10-year follow-up. The Birkebeiner Ageing Study and the Tromso Study
- 2022
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Ingår i: Open Heart. - : BMJ. - 2053-3624. ; 9:2
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Tidskriftsartikel (refereegranskat)abstract
- AimsEndurance sport practice is associated with a high prevalence of atrial fibrillation (AF), which increases the risk of stroke in the general population. However, stroke risk in endurance athletes with AF is sparsely investigated. Most studies have been limited by design and are largely restricted to younger and middle-aged populations. Thus, we aimed to investigate AF and stroke risk in older athletes exposed to prolonged endurance training.MethodDuring a 10-year period, 505 male athletes aged >= 65 years frequently participating in a long-distance ski race were compared with 1867 men of the same age from the general population. The main exposure was endurance sport practice with self-reported AF and stroke as outcomes. Stroke risk was further examined by joint modelling of AF and endurance practice. Statistical analysis was conducted with a modified Poisson model.ResultsAthletes (median age: 68, range: 65-90) participated in a long-distance ski race over a median of 14 years (range: 1-53). Prevalence (28.5% vs 17.8%) and adjusted risk of AF (risk ratio (RR): 1.88, 95% CI: 1.49 to 2.37) were higher in athletes compared with non-athletes, whereas the prevalence (5.4% vs 9.7%) and risk of stroke were lower (RR: 0.60, 95% CI: 0.37 to 0.95). Compared with athletes without AF, risk of stroke was twofold in athletes (RR: 2.38, 95% CI: 1.08 to 5.24) and nearly fourfold in non-athletes (RR: 3.87, 95% CI: 1.98 to 7.57) with AF.ConclusionAlthough older male endurance athletes experienced an increased risk of AF, the long-term risk of stroke was substantially reduced compared with non-athletes.
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| 2. |
- Klingberg, Sofia, 1979, et al.
(författare)
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Loss of height predicts total and cardiovascular mortality: a cohort study of northern European women
- 2021
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Ingår i: BMJ Open. - : BMJ. - 2044-6055. ; 11:8
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Tidskriftsartikel (refereegranskat)abstract
- Objective To examine height changes in middle-aged northern European women in relation to overall and cardiovascular mortality. Design Population-based cohort studies with longitudinally measured heights and register-based mortality. Setting Sweden and Denmark. Participants Population-based samples of 2406 Swedish and Danish women born on selected years in 1908-1952, recruited to baseline examinations at ages 30-60, and re-examined 10-13 years later. Main outcome measure Total and cardiovascular disease (CVD) specific mortality during 17-19 years of follow-up after last height measure. Results For each 1 cm height loss during 10-13 years, the HR (95% CI) for total mortality was 1.14 (1.05 to 1.23) in Swedish women and 1.21 (1.09 to 1.35) in Danish women, independent of key covariates. Low height and high leisure time physical activity at baseline were protective of height loss, independent of age. Considering total mortality, the HR for major height loss, defined as height loss greater than 2 cm, were 1.74 (1.32 to 2.29) in Swedish women and 1.80 (1.27 to 2.54) in Danish women. Pooled analyses indicated that height loss was monotonically associated with an increased mortality, confirming a significant effect above 2 cm height loss. For cause-specific mortality, major height loss was associated with a HR of 2.31 (1.09 to 4.87) for stroke mortality, 2.14 (1.47 to 3.12) for total CVD mortality and 1.71 (1.28 to 2.29) for mortality due to causes other than CVD. Conclusion Height loss is a marker for excess mortality in northern European women. Specifically the hazard of CVD mortality is increased in women with height loss during middle age, and the results suggest that the strongest cause-specific endpoint may be stroke mortality. The present findings suggest attention to height loss in early and mid-adulthood to identify women at high risk of CVD, and that regular physical activity may prevent early onset height loss.
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| 3. |
- Lavall, Rodrigo L., et al.
(författare)
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An unprecedented hybrid polyoxometalate based on niobium oligomers: A notable application as redox supercapacitor electrode
- 2023
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Ingår i: Chemical Engineering Journal. - : ELSEVIER SCIENCE SA. - 1385-8947 .- 1873-3212. ; 455
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Tidskriftsartikel (refereegranskat)abstract
- An unprecedented polyoxoniobate (PONb) oligomer was obtained by addition of a methylene blue (MB) dye solution over the PONb solution formed a blue nanogel that was converted into a stable blue solid through a lyophilization process. The new solid composite, so-called "blue polyoxoniobate" (blue-PONb), presents a two-dimensional (2D) morphology with electrochemical performance that stand out among the materials used in redox supercapacitor technology. This new material was evaluated as supercapacitor electrode showing a high areal specific capacitance and power density that reaches 110.50 mF cm(-2) and 8.49 mW cm(-2). In addition, in this composite the redox additive (MB) and the PONb presented a peculiar electrochemical behavior, the reduction of the niobium species and the transfer of electrons necessary for the accumulation of charge occurring simultaneously. As a result, blue-PONb electrode maintains the cycling performance with high coulombic effi-ciency (similar to 99 %) over the 50,000 cycles evaluated. Here, the origins of the electrochemical stability and the mechanism of operation of the blue-PONb electrode are analyzed and discussed. Finally, this work presents a PONb as a new and promising class of redox-capacitive materials with matrix/redox shuttle synergism.
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