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| 2. |
- Aksyutina, Yu, et al.
(författare)
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Lithium isotopes beyond the drip line
- 2008
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Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693. ; 666:5, s. 430-434
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Tidskriftsartikel (refereegranskat)abstract
- The unbound isotopes 10Li, 12Li and 13Li have been observed after nucleon-knockout reactions at relativistic energies with 11Li and 14Be beams impinging on a liquid hydrogen target. The channels , and were analysed in the ALADIN-LAND setup at GSI. The 10Li data confirm earlier findings, while the 12Li and 13Li nuclei were observed for the first time. The relative-energy spectrum shows that the ground state of 12Li can be described as a virtual s-state with a scattering length of -13.7(1.6) fm. A broad energy spectrum was found for the channel. Based on the assumption that the relative-energy spectrum is dominated by a correlated background presumably stemming from initial correlations in the 14Be ground-state, evidence for a 13Li resonance at 1.47(31) MeV above the threshold with a width around 2 MeV has been found.
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| 4. |
- Buervenich, Silvia, et al.
(författare)
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A rare truncating mutation in ADH1C (G78Stop) shows significant association with Parkinson disease in a large international sample.
- 2005
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Ingår i: Archives of neurology. - : American Medical Association (AMA). - 0003-9942. ; 62:1, s. 74-8
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Alcohol dehydrogenases (ADHs) may be involved in the pathogenesis of neurodegenerative disorders because of their multiple roles in detoxification pathways and retinoic acid synthesis. In a previous study, significant association of an ADH class IV allele with Parkinson disease (PD) was found in a Swedish sample. PATIENTS: The previously associated single-nucleotide polymorphism plus 12 further polymorphisms in the ADH cluster on human chromosome 4q23 were screened for association in an extension of the original sample that now included 123 Swedish PD patients and 127 geographically matched control subjects. A rare nonsense single-nucleotide polymorphism in ADH1C (G78stop, rs283413) was identified in 3 of these patients but in no controls. To obtain sufficient power to detect a possible association of this rare variant with disease, we screened a large international sample of 1076 PD patients of European ancestry and 940 matched controls. RESULTS: The previously identified association with an ADH class IV allele remained significant (P<.02) in the extended Swedish study. Furthermore, in the international collaboration, the G78stop mutation in ADH1C was found in 22 (2.0%) of the PD patients but only in 6 controls (0.6%). This association was statistically significant (chi(2)(1) = 7.5; 2-sided P = .007; odds ratio, 3.25 [95% confidence interval, 1.31-8.05]). In addition, the G78stop mutation was identified in 4 (10.0%) of 40 Caucasian index cases with PD with mainly hereditary forms of the disorder. CONCLUSION: Findings presented herein provide further evidence for mutations in genes encoding ADHs as genetic risk factors for PD.
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| 5. |
- Dyrssen, Catharina, 1949, et al.
(författare)
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Buller kan inte byggas bort
- 2005
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Ingår i: Arkitekten. - Stockholm : Arkitektförbundet. - 0347-058X. ; 2005:3, s. 52-:4, s. 52-52
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 6. |
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| 7. |
- Hellström, Björn, 1959-, et al.
(författare)
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Acoustic Design Artifacts and Methods for Urban Soundscapes
- 2008
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Ingår i: The 15th International Congress on Sound and Vibration In: International Journal of Acoustics & Vibration. ; , s. 52-52
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Konferensbidrag (refereegranskat)abstract
- The research question is: “How to develop and apply acoustic artifacts and design methodologies for improving soundscapes in urban outdoor spaces?” In the project, this research question is limited to two specific types of urban outdoor spaces – city-park and city-square – and to two types of acoustic design artifacts. These are: I. Dynamic promotion of qualitative site specific sounds (e.g., the overall site specific sonic atmosphere, sounds from human activities, birds and fountains), which creates an improved soundscape. II. Sound-art installations, that creates delimited auditory sub-spaces within the park/square. The purpose and method is: 1. To provide two case-studies of artistic soundscape improvement, one in a noise polluted city-park and one in a city-square. The case-studies will serve as models for future applications of the new acoustic design artifacts. 2. To create and validate an innovative acoustic design methodology based on state-of-the-art real-time acoustic simulation tools integrated into the design process. The methodology will be validated in psychoacoustic listening experiments and field studies. 3. To determine the potential of the two acoustic design artifacts (I Dynamic promotion of qualitative site specific sounds, and II Sound-art installations) for providing pleasant and restorative soundscapes, in order to strengthening the social interaction as well as the spatial and aesthetical qualities in noise polluted city parks/squares. The present project beats a new track by combining acoustic design with sound art research, integrating methodologies based on real-time acoustic simulation and application of psychoacoustic methodology for validating simulations and for evaluating perceptual, emotional and behavioural effects on visitors to public open spaces. The ongoing research project, financed by the Swedish Research Council, is executed by the University College of Arts, Crafts and Design (Konstfack), Gösta Ekman Laboratory – Stockholm University and Karolinska Institutet and the Interactive Institute, all in Stockholm, Sweden.
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| 8. |
- Hellström, Björn, 1959-
(författare)
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Acoustic design Artifacts and Methods for Urban Soundscapes
- 2009
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Ingår i: Proceedings of a meeting held 5-9 July 2009, Krakow, Poland.. - : International Institute of Acoustics and Vibration (IIAV). - 9781615677368 ; , s. 1-8
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Konferensbidrag (refereegranskat)abstract
- The research question is: "How to develop and apply acoustic artefacts and design method-ologies for improving soundscapes in urban outdoor spaces?" In the project, this research question is limited to one specific type of urban outdoor space – city-park – and to two types of acoustic design artefacts. These are: I. Dynamic promotion of qualitative site specific sounds (e.g., the overall site specific sonic atmosphere, sounds from activities, birds and fountains), which creates an improved soundscape. II. Sound-art installations, that creates de-limited auditory sub-spaces within the park/square.
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| 9. |
- Hellström, Björn, 1959-
(författare)
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Acoustic design in Commercial Space
- 2006
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Ingår i: ICSV13 Proceedings.
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Konferensbidrag (refereegranskat)abstract
- The starting point for this paper is to discuss and challenge the visual dominance in architectural thinking, and to raise competence among architects and planners on sound and sound environment issues. To promote a sustainable urban environment,sounds must be integrated in the complexity of urban design and development. Therefore,it is especially important to integrate acoustic and architectural analysis.The paper focuses on urban public space as well as indoor public pathways, communication space and semi-public commercial space, e.g. shopping malls, wherereliability on sonic orientation may be crucial. For these kinds of collective spaces, I argue, it is especially important to integrate acoustic and architectural analysis. Their sonic conditions are often loud, blurred, and confusing, with little correspondence between visual and aural perception, and with weak articulations of spatial dimension, distance, borders, and orientation. If not cared for, the result may be increasing sound disturbance, lack of people’s moving through the areas, dangerous differences between day and night use, disorientation for several user groups, and segregation.The paper is integrated in the ongoing research project, Transmission, executed by Urban Sound Institute (USIT), financed by Swedish Research Council. Results will hopefully deliver good examples and operative methods to be used by architects, planners and acousticians. The paper is also a result of ongoing projects and research at the acoustic consultancy company Ingemansson Technology AB, Sweden
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