| 1. |
- Kueppers, Michael, et al.
(författare)
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Triple F-a comet nucleus sample return mission
- 2009
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Ingår i: Experimental astronomy. - : Springer Science and Business Media LLC. - 0922-6435 .- 1572-9508. ; 23:3, s. 809-847
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Tidskriftsartikel (refereegranskat)abstract
- The Triple F (Fresh From the Fridge) mission, a Comet Nucleus Sample Return, has been proposed to ESA's Cosmic Vision program. A sample return from a comet enables us to reach the ultimate goal of cometary research. Since comets are the least processed bodies in the solar system, the proposal goes far beyond cometary science topics (like the explanation of cometary activity) and delivers invaluable information about the formation of the solar system and the interstellar molecular cloud from which it formed. The proposed mission would extract three sample cores of the upper 50 cm from three locations on a cometary nucleus and return them cooled to Earth for analysis in the laboratory. The simple mission concept with a touch-and-go sampling by a single spacecraft was proposed as an M-class mission in collaboration with the Russian space agency ROSCOSMOS.
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| 2. |
- Henkel, C., et al.
(författare)
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The density, the cosmic microwave background, and the proton-to-electron mass ratio in a cloud at redshift 0.9
- 2009
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 500:2, s. 725-734
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Tidskriftsartikel (refereegranskat)abstract
- Based on measurements with the Effelsberg 100-m telescope, a multi-line study of molecular species is presented toward the gravitational lens system PKS 1830-211, which is by far the best known target to study dense cool gas in absorption at intermediate redshift. Determining average radial velocities and performing Large Velocity Gradient radiative transfer calculations, the aims of this study are (1) to determine the density of the gas, (2) to constrain the temperature of the cosmic microwave background (CMB), and (3) to evaluate the proton-to-electron mass ratio at redshift z ˜ 0.89. Analyzing data from six rotational HC3N transitions (this includes the J=7≤ftarrow6 line, which is likely detected for the first time in the interstellar medium) we obtain n(H2) ~ 2600 cm-3 for the gas density of the south-western absorption component, assuming a background source covering factor, which is independent of frequency. With a possibly more realistic frequency dependence proportional to ν0.5 (the maximal exponent permitted by observational boundary conditions), n(H2) ~ 1700 cm-3. Again toward the south-western source, excitation temperatures of molecular species with optically thin lines and higher rotational constants are, on average, consistent with the expected temperature of the cosmic microwave background, T_CMB = 5.14 K. However, individually, there is a surprisingly large scatter which far surpasses expected uncertainties. A comparison of CS J =1 ≤ftarrow0 and 4≤ftarrow3 optical depths toward the weaker north-western absorption component results in T_ex = 11 K and a 1-σ error of 3 K. For the main component, a comparison of velocities determined from ten optically thin NH3 inversion lines with those from five optically thin rotational transitions of HC3N, observed at similar frequencies, constrains potential variations of the proton-to-electron mass ratio μ to Δμ / μ
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| 3. |
- Kirsanova, M.S., et al.
(författare)
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Study of triggered star formation around HII region S235
- 2007
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Ingår i: Proceedings of "Millimeter wave astronomy and star formation", ed. I. Zinchenko, Nizhny Novgorod, Russia, August 2007, Inst. of Applied Physics RAS. ; , s. 23-29
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 4. |
- Henkel, Herbert, et al.
(författare)
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Avike bay - a 10 km diameter possible impact structure at the Bothnian Sea coast of central Sweden.
- 2005
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Ingår i: IMPACT TECTONICS. - Berlin/Heidelberg : Springer-Verlag. - 3540241817 ; , s. 323-340
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Konferensbidrag (refereegranskat)abstract
- Avike Bay is a 270 degrees degree wide near-circular, 114 in deep bay on the Swedish coast of the Bothnian Sea, northeast of Sundsvall. The structure has a diameter of about 10 km. It was classified as a probable impact structure because of its extraordinary circular topography in the overwiew of impact structures in Fennoscandia. Recent studies lend further support to this interpretation. The structure has a submarine central mound, which is elevated some 40 in above the adjacent sea floor. It has a very distinct tangential and radial on-shore fracture pattern as seen in the topographic map. Along the southwestern shore of the Bay, an enigmatic quartzite breccia of unknown age occurs as part of a larger outcrop of polymict breccia with clasts of crystalline rocks and quartzite of unknown age. In thin section, planar fractures can be observed in quartz and feldspar grains. A detailed investigation showed that in a few cases the quartz grains contained microdeformation features closely resembling PDFs.
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| 5. |
- Henkel, M, et al.
(författare)
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Service collaboration environment
- 2006
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Ingår i: Proceedings of the International Workshop on E-Services in Public Administration.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The extended use of services for cross enterprise collaboration rely on that the use and provisioning of services are simple, and yet that the provided services follows a coherent set of rules for their behaviour and interaction. This balance between simplicity and regulation is crucial for the stepwise evolution of both business and software services. In this paper we present the concept of a service collaboration environment to denote a domain of services working under a limited set of regulations. We use the theory of competitive market forces to define a set of guidelines that aims to enable service growth by stimulating new service consumers and providers to enter the environment. Furthermore, the guidelines, being both technical and business oriented, can be applied to balance the competitive forces from service consumers and providers.
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| 6. |
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| 7. |
- Wiltfang, J., et al.
(författare)
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Consensus Paper of the WFSBP Task Force on Biological Markers of Dementia : The role of CSF and blood analysis in the early and differential diagnosis of dementia
- 2009
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Ingår i: Revista de Psiquiatria Clinica. - 0101-6083. ; 36, s. 1-16
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Forskningsöversikt (refereegranskat)abstract
- Aging of population, and increasing life expectancy result in an increasing number of patients with dementia. This symptom can be a part of a completely curable disease of the central nervous system (e.g, neuroinflammation), or a disease currently considered irreversible (e.g, Alzheimer's disease, AD). In the latter case, several potentially successful treatment approaches are being tested now, demanding reasonable standards of pre-mortem diagnosis. Cerebrospinal fluid and serum analysis (CSF/serum analysis), whereas routinely performed in neuroinflammatory diseases, still requires standardization to be used as an aid to the clinically based diagnosis of AD. Several AD-related CSF parameters (total tau, phosphorylated forms of tau, A beta peptides, ApoE genotype, p97, etc.) tested separately or in a combination provide sensitivity and specificity in the range of 85%, the figure commonly expected from a good diagnostic tool. In this review, recently published reports regarding progress in neurochemical pre-mortem diagnosis of dementias are discussed with a focus on an early and differential diagnosis of AD. Novel perspectives offered by recently introduced technologies, e.g, fluorescence correlation spectroscopy (FCS) and surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) are briefly discussed.
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| 8. |
- Wiltfang, J, et al.
(författare)
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Consensus paper of the WFSBP Task Force on Biological Markers of Dementia: the role of CSF and blood analysis in the early and differential diagnosis of dementia.
- 2005
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Ingår i: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. - : Informa UK Limited. - 1562-2975. ; 6:2, s. 69-84
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Forskningsöversikt (refereegranskat)abstract
- Aging of population, and increasing life expectancy result in an increasing number of patients with dementia. This symptom can be a part of a completely curable disease of the central nervous system (e.g, neuroinflammation), or a disease currently considered irreversible (e.g, Alzheimer's disease, AD). In the latter case, several potentially successful treatment approaches are being tested now, demanding reasonable standards of pre-mortem diagnosis. Cerebrospinal fluid and serum analysis (CSF/serum analysis), whereas routinely performed in neuroinflammatory diseases, still requires standardization to be used as an aid to the clinically based diagnosis of AD. Several AD-related CSF parameters (total tau, phosphorylated forms of tau, Abeta peptides, ApoE genotype, p97, etc.) tested separately or in a combination provide sensitivity and specificity in the range of 85%, the figure commonly expected from a good diagnostic tool. In this review, recently published reports regarding progress in neurochemical pre-mortem diagnosis of dementias are discussed with a focus on an early and differential diagnosis of AD. Novel perspectives offered by recently introduced technologies, e.g, fluorescence correlation spectroscopy (FCS) and surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) are briefly discussed.
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