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- Frassinetti, Lorenzo, et al.
(författare)
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Cold pulse propagation in a reversed-field pinch
- 2007
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Ingår i: Nuclear Fusion. - : IOP Publishing. - 0029-5515 .- 1741-4326. ; 47:2, s. 135-145
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Tidskriftsartikel (refereegranskat)abstract
- The cold pulse propagation is a powerful tool for the study of heat transport and the determination of perturbative electron heat diffusivity chi(CP)(e). In this paper the experimental study of cold pulses generated by pellet injection in a reversed-field pinch device is described. The most common phenomenology is an inward cold pulse propagation, from the edge to the core; however, we will describe that outward propagation can occur if the pellet ablates up to the plasma centre. A model to simulate the dynamics of the pulse (i.e. the relation between the arrival time of the pulse and its radial position) has been developed. With this model it is possible to explain the cold pulse phenomenologies as well as to estimate chi(CP)(e) in the plasma core. The heat diffusivity in standard and enhanced confinement plasmas has been determined and compared; in standard regimes chi(CP)(e) is three times larger than in enhanced confinement regimes. Finally, it has been possible to confirm a scaling between diffusivity and magnetic stochasticity.
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- Frassinetti, Lorenzo, et al.
(författare)
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Turbulence and particle confinement in a reversed-field pinch plasma
- 2007
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Ingår i: Plasma Physics and Controlled Fusion. - : IOP Publishing. - 0741-3335 .- 1361-6587. ; 49:3, s. 199-209
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Tidskriftsartikel (refereegranskat)abstract
- The confinement properties of a reversed-field pinch ( RFP) device are limited by the high level of magnetic stochasticity produced by the interaction of tearing modes in the plasma core. Away to reduce the core magnetic stochasticity is the application of the pulsed poloidal current drive ( PPCD) technique. By applying the PPCD, tearing modes are stabilized, magnetic stochasticity and turbulence are reduced and hence the confinement is enhanced. In the TPE-RX device, standard RFP plasmas are characterized by magnetic and electrostatic edge turbulence dominated by intermittent phenomena; on the contrary, the improved confinement regime generated by the PPCD is characterized by turbulence with a self-similar nature. We show that the increase in tau(p) is well correlated with the change in the nature of both the magnetic and the electrostatic turbulence. While plasmas with low confinement are dominated by intermittent events and by magnetic and electrostatic activity with a non-self-similar nature, plasmas with high confinement show turbulence with a self-similar character.
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- Horvath, Rita, et al.
(författare)
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Molecular basis of infantile reversible cytochrome c oxidase deficiency myopathy.
- 2009
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Ingår i: Brain : a journal of neurology. - : Oxford University Press (OUP). - 1460-2156. ; 132:Pt 11, s. 3165-74
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Tidskriftsartikel (refereegranskat)abstract
- Childhood-onset mitochondrial encephalomyopathies are usually severe, relentlessly progressive conditions that have a fatal outcome. However, a puzzling infantile disorder, long known as 'benign cytochrome c oxidase deficiency myopathy' is an exception because it shows spontaneous recovery if infants survive the first months of life. Current investigations cannot distinguish those with a good prognosis from those with terminal disease, making it very difficult to decide when to continue intensive supportive care. Here we define the principal molecular basis of the disorder by identifying a maternally inherited, homoplasmic m.14674T>C mt-tRNA(Glu) mutation in 17 patients from 12 families. Our results provide functional evidence for the pathogenicity of the mutation and show that tissue-specific mechanisms downstream of tRNA(Glu) may explain the spontaneous recovery. This study provides the rationale for a simple genetic test to identify infants with mitochondrial myopathy and good prognosis.
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