| 1. |
- Aad, G., et al.
(författare)
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- 2012
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swepub:Mat__t (refereegranskat)
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| 2. |
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| 3. |
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| 4. |
- Schmoll, H. J., et al.
(författare)
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ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making
- 2012
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Ingår i: Annals of Oncology. - : Elsevier BV. - 0923-7534 .- 1569-8041. ; 23:10, s. 2479-2516
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Tidskriftsartikel (refereegranskat)abstract
- Colorectal cancer (CRC) is the most common tumour type in both sexes combined in Western countries. Although screening programmes including the implementation of faecal occult blood test and colonoscopy might be able to reduce mortality by removing precursor lesions and by making diagnosis at an earlier stage, the burden of disease and mortality is still high. Improvement of diagnostic and treatment options increased staging accuracy, functional outcome for early stages as well as survival. Although high quality surgery is still the mainstay of curative treatment, the management of CRC must be a multi-modal approach performed by an experienced multi-disciplinary expert team. Optimal choice of the individual treatment modality according to disease localization and extent, tumour biology and patient factors is able to maintain quality of life, enables long-term survival and even cure in selected patients by a combination of chemotherapy and surgery. Treatment decisions must be based on the available evidence, which has been the basis for this consensus conference-based guideline delivering a clear proposal for diagnostic and treatment measures in each stage of rectal and colon cancer and the individual clinical situations. This ESMO guideline is recommended to be used as the basis for treatment and management decisions.
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| 5. |
- Keys, Patrick W., et al.
(författare)
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Analyzing precipitationsheds to understand the vulnerability of rainfall dependent regions
- 2012
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Ingår i: Biogeosciences. - : Copernicus GmbH. - 1726-4170 .- 1726-4189. ; 9:2, s. 733-746
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Tidskriftsartikel (refereegranskat)abstract
- It is well known that rivers connect upstream and downstream ecosystems within watersheds. Here we describe the concept of precipitationsheds to show how upwind terrestrial evaporation source areas contribute moisture for precipitation to downwind sink regions. We illustrate the importance of upwind land cover in precipitationsheds to sustain precipitation in critically water stressed downwind areas, specifically dryland agricultural areas. We first identify seven regions where rainfed agriculture is particularly vulnerable to reductions in precipitation, and then map their precipitationsheds. We then develop a framework for qualitatively assessing the vulnerability of precipitation for these seven agricultural regions. We illustrate that the sink regions have varying degrees of vulnerability to changes in upwind evaporation rates depending on the extent of the precipitationshed, source region land use intensity and expected land cover changes in the source region.
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| 6. |
- Wimmer, K., et al.
(författare)
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Identification of the slow E3 transition (136)C(s)(m)->(136)Cs with conversion electrons
- 2011
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 84:1, s. 014329-
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Tidskriftsartikel (refereegranskat)abstract
- We performed at ISOLDE the spectroscopy of the decay of the 8(-) isomer in (136)Cs by. and conversion-electron detection. For the first time the excitation energy of the isomer and the multipolarity of its decay have been measured. The half-life of the isomeric state was remeasured to T(1/2) = 17.5(2) s. This isomer decays via a very slow 518-keV E3 transition to the ground state. In addition to this, a much weaker decay branch via a 413-keV M4 and a subsequent 105-keV E2 transition has been found. Thus we have found a new level at 105 keV with spin 4(+) between the isomeric and the ground state. The results are discussed in comparison to shell-model calculations.
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