| 1. |
- Blomqvist, My, et al.
(författare)
-
How do children with attention deficit hyperactivity disorder interact in a clinical dental examination? : A video analysis.
- 2005
-
Ingår i: European Journal of Oral Sciences. - : Wiley. - 0909-8836 .- 1600-0722. ; 113:3, s. 203-209
-
Tidskriftsartikel (refereegranskat)abstract
- Attention deficit hyperactivity disorder (ADHD) is currently the most common behavioural disorder in school-age children. The aim of this study was to perform a detailed analysis of behavioural interactions between the dentist and the child patient with ADHD. All children born in 1991(n=555) in one Swedish municipality were screened for attention and learning problems and assessed for ADHD: Twenty-two children with ADHD and a control group of 47 children without attention and learning problems were included in the study. The dental recall visit was recorded on video. The interaction between the dentist and the child was analyzed in detail and scored as verbal and nonverbal initiatives and responses. Compared to the children in the control group, the children with ADHD made significantly more initiatives, especially initiatives that did not focus on the eaxmination or the dentist. The children with ADHD had fewer verbal responses and more missing responses. In conclusion, the problems in communication resulted in less two-way communication between the dentist and the children with ADHD than the interaction between the dentist and the children in the control group. The children with ADHD had particular difficulties staying focused on the examination.
|
|
| 2. |
- Carlsén, Stefan, et al.
(författare)
-
Cartilage oligomeric matrix protein induction of chronic arthritis in mice
- 2008
-
Ingår i: Arthritis and Rheumatism. - : Wiley. - 0004-3591 .- 1529-0131. ; 58:7, s. 2000-2011
-
Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To develop a new mouse model for arthritis using cartilage oligomeric matrix protein (COMP) and to study the role of major histocompatibility complex (MHC) and Ncf1 genes in COMP-induced arthritis (COMPIA). METHODS: Native (pentameric) and denatured (monomeric) COMP purified from a rat chondrosarcoma was injected into mice with Freund's adjuvant to induce arthritis. C3H.NB, C3H.Q, B10.P, B10.Q, (B10.Q x DBA/1)F1, (BALB/c x B10.Q)F1, Ncf1 mutated, H-2Aq, H-2Ap, and human DR4+-transgenic mice were used. Anti-COMP antibodies and COMP levels in the immune sera were analyzed, and passive transfer of arthritis with purified immune sera was tested. RESULTS: Immunization with rat COMP induced a severe, chronic, relapsing arthritis, with a female preponderance, in the mice. The disease developed in C3H.NB mice, but not in B10.P mice, although they share the same MHC haplotype. Both H-2q and H-2p MHC haplotypes allowed the initiation of COMPIA. Using H-2Aq-transgenic and H-2Ap-transgenic mice, we demonstrated a role of both the Aq and Ep class II molecules in this model. Interestingly, the introduction of a mutation in the Ncf1 gene, which is responsible for the reduced oxidative burst phenotype, into the COMPIA-resistant B10.Q mouse strain rendered them highly susceptible to arthritis. In addition, the transfer of anti-COMP serum was found to induce arthritis in naive mice. Mice transgenic for the rheumatoid arthritis (RA)-associated DR4 molecule were found to be highly susceptible to COMPIA. CONCLUSION: Using rat COMP, we have developed a new and unique mouse model of chronic arthritis that resembles RA. This model will be useful as an appropriate and alternative model for studying the pathogenesis of RA.
|
|
| 3. |
- Hertz, Hans M., et al.
(författare)
-
Laboratory X-ray micro- and nano-imaging
- 2009
-
Ingår i: Frontiers in Optics (FiO) 2009. - Washington, D.C. : Optical Society of America. - 9781557528780
-
Konferensbidrag (refereegranskat)abstract
- We summarize recent progress in laboratory x-ray imaging systems based on compact high-brightness liquid-jet sources, including <25 nm soft x-ray zone-plate microscopy and <10 μm (lens-free) hard x-ray phase-contrast imaging.
|
|
| 4. |
- Hertz, Hans M., et al.
(författare)
-
Laboratory x-ray micro imaging : Sources, optics, systems and applications
- 2009
-
Ingår i: Journal of Physics, Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 186
-
Tidskriftsartikel (refereegranskat)abstract
- We summarize the recent progress in laboratory-scale soft and hard x-ray micro imaging in Stockholm. Our soft x-ray work is based on liquid-jet laser-plasma sources which are combined with diffractive and multilayer optics to form laboratory x-ray microscopes. In the hard x-ray regime the imaging is based on a liquid-metal-jet electron-impact source which provides the necessary coherence to allow phase-contrast imaging with high fidelity.
|
|
| 5. |
- Holmberg, Andreas, 1982-, et al.
(författare)
-
A test rig and experimental procedure to determine the aeroacoustic properties of a splitter plate
- 2009
-
Ingår i: 15th AIAA/CEAS Aeroacoustics Conference (30th AIAA Aeroacoustics Conference). - 9781563479748 ; , s. 2009-3258-
-
Konferensbidrag (refereegranskat)abstract
- A test rig for a study of aero-acoustic phenomena over a sharp edge inside a duct is developed and described. The aero-acoustic losses over the edge are experimentally determined in quiescent air by measurements of a three-port, from which a power balance analysis yields the dissipated acoustic energy. The phenomenon of interest is interaction between the vortices shed by an acoustic wave propagating over a sharp edge and the wave itself. However, this phenomenon require high levels of particle velocity. The levels achieved are low, thus the dominating losses seen in the results are instead due to transfer of acoustic energy from sound waves into vibration energy in the splitter plate. This fact was observed by calculating the two-port scattering matrix over each sidebranch.
|
|
| 6. |
|
|
| 7. |
- Holmberg, Hans-Christer, 1958-, et al.
(författare)
-
Tekniken som analyserar eliten
- 2008
-
Ingår i: Skidsport. - Stockholm : Media text network. ; :2, s. 36-38
-
Tidskriftsartikel (populärvet., debatt m.m.)
|
|
| 8. |
|
|
| 9. |
- Holmberg, Johan, et al.
(författare)
-
One-year follow-up of cognitive behavioral therapy for phobic postural vertigo
- 2007
-
Ingår i: Journal of Neurology. - : Springer Science and Business Media LLC. - 1432-1459 .- 0340-5354. ; 254:9, s. 1189-1192
-
Tidskriftsartikel (refereegranskat)abstract
- Background Phobic postural vertigo is characterized by dizziness in standing and walking despite normal clinical balance tests. Patients sometimes exhibit anxiety reactions and avoidance behavior to specific stimuli. Different treatments are possible for PPV, including vestibular rehabilitation exercises, pharmacological treatment, and cognitive behavioral therapy. We recently reported significant benefits of cognitive behavioural therapy for patients with phobic postural vertigo. This study presents the results of a one-year follow-up of these patients. Methods Swedish translations of the following questionnaires were administered: (Dizziness Handicap Inventory, Vertigo Symptom Scale, Vertigo Handicap Questionnaire, and Hospital Anxiety and Depression Scale) were administered to 20 patients (9 men and 11 women; mean age 43 years, range 23-59 years) one year after completion of cognitive behavioral therapy. Results Test results were similar to those obtained before treatment, showing that no significant treatment effects remained. Conclusion Cognitive behavioral therapy has a limited long-term effect on phobic postural vertigo. This condition is more difficult to treat than panic disorder with agoraphobia. Vestibular rehabilitation exercises and pharmacological treatment might be the necessary components of treatment.
|
|
| 10. |
- Holmberg, Johan, et al.
(författare)
-
Reduced postural differences between phobic postural vertigo patients and healthy subjects during a postural threat.
- 2009
-
Ingår i: Journal of Neurology. - : Springer Science and Business Media LLC. - 1432-1459 .- 0340-5354. ; 256, s. 1258-1262
-
Tidskriftsartikel (refereegranskat)abstract
- Phobic postural vertigo is characterized by subjective imbalance and dizziness while standing or walking, despite normal values for clinical balance tests. Patients with phobic postural vertigo exhibit an increased high-frequency sway in posturographic tests. Their postural sway, however, becomes similar to the sway of healthy subjects during difficult balance tasks. Posturographic recordings of 30 s of quiet stance was compared to recordings of 30 s of quiet stance during a postural threat, which consisted of the knowledge of forthcoming vibratory calf muscle stimulation, in 37 consecutive patients with phobic postural vertigo and 24 healthy subjects. During quiet stance without the threat of forthcoming vibratory stimulation, patients with phobic postural vertigo exhibited a postural sway containing significantly more high-frequency sway than the healthy subjects. During the quiet stance with forthcoming vibratory stimulation, i.e., anticipation of a postural threat, the significant differences between groups disappeared for all variables except sagittal high-frequency sway. During postural threat, healthy subjects seemed to adopt a postural strategy that was similar to that exhibited by phobic postural vertigo patients. The lack of additional effects facing a postural threat among phobic postural vertigo patients may be due to an already maximized postural adaptation. Deviant postural reactions among patients with phobic postural vertigo may be considered as an avoidant postural response due to a constant fear of losing postural control.
|
|
