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Träfflista för sökning "WFRF:(Holmgren Christina) srt2:(2010-2014)"

Sökning: WFRF:(Holmgren Christina) > (2010-2014)

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1.
  • Andersson, Annika, 1981, et al. (författare)
  • Participation in leisure activities and binge drinking in adults – findings from a Swedish general population sample.
  • 2012
  • Ingår i: Addiction Research & Theory. - : Informa UK Limited. - 1606-6359 .- 1476-7392. ; 20:2, s. 172-182
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this cross-sectional study was to estimate the associations between participation in different leisure activities and binge drinking in Swedish adults. The study was based on a questionnaire in a general population sample (n=3567) of individuals aged 19–64 years old. Men and women were defined as binge drinkers if they reported that they had consumed alcohol at least once a month, and stated that at a typical drinking occasion they consumed five or more standard glasses (12g of alcohol). Multivariate analyses found associations between binge drinking and socializing with friends among men aged 19–30 years (odds ratio, OR 2.88), in the 31–64 years old age group (OR 1.87). Corresponding results was found in younger women (OR 2.36). A higher OR was also found for younger men who regularly attended sporting events as spectators (OR 1.83), and among respondents in the older age group who regularly played computer or video games (OR 2.11 for women and 1.61 for men). A lower OR for binge drinking was found for men who regularly participated in religious services in both age-groups. Lower prevalence of binge drinking among women was only found in the younger group among those who regularly participated in sports/athletics or other training (OR 0.51). Our findings suggest that prevention strategies could benefit from an everyday life approach, but also that different interventions should be used in relation to specific leisure activities.
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2.
  • Holmgren, Christina M, et al. (författare)
  • Changes in Medication Preceding Out-of-hospital Cardiac Arrest Where Resuscitation Was Attempted
  • 2014
  • Ingår i: Journal of Cardiovascular Pharmacology. - : Lippincott Williams & Wilkins. - 0160-2446 .- 1533-4023. ; 63:6, s. 497-503
  • Tidskriftsartikel (refereegranskat)abstract
    • Objective: To describe recent changes in medication preceding out-of-hospital cardiac arrest (OHCA) where resuscitation was attempted. Methods: OHCA victims were identified by the Swedish Cardiac Arrest Register and linked by means of their unique 10-digit personal identification numbers to the Prescribed Drug Register. We identified new claimed prescriptions during a 6-month period before the OHCA compared with those claimed in the period 12 to 18 months before. The 7-digit Anatomical Therapeutical Chemical codes of individual drugs were used. The study period was November 2007-January 2011. Results: OHCA victims with drugs were (1) older than those who did not claim any drugs in any period (70 +/- 16 years vs. 54 +/- 22 years, P < 0.001), (2) more often women (34% vs. 20%, P < 0.001), and (3) had more often a presumed cardiac etiology (67% vs. 54%, P < 0.001). The OHCA victims were less likely to have ventricular tachycardia/ventricular fibrillation as the first recorded ;rhythm (26% vs. 33%, P < 0.001) or to survive 1 month (9% vs. 17%, P < 0.0001). New prescriptions were claimed by 5122 (71%) of 7243 OHCA victims. The most frequently claimed new drugs were paracetamol (acetaminophen) 10.3%, furosemide 7.8%, and omeprazole 7.6%. Of drugs known or supposed to cause QT prolongation, ciprofloxacin was the most frequent (3.4%) altogether; 16% had a new claimed prescription of a drug included in the "qtdrugs.org" lists. Conclusions: Most OHCA victims had new drugs prescribed within 6 months before the event but most often intended for diseases other than cardiac. No claims can be made as to the causality.
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3.
  • Holmgren, Christina M (författare)
  • On the causes of ventricular arrhythmia, its treatment and outcome
  • 2011
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • On the causes of ventricular arrhythmia, its treatment and outcome Christina Holmgren Institute of Medicine Sahlgrenska Academy at University of Gothenburg Göteborg, Sweden ABSTRACT Background: Ventricular arrhythmia is the most common aetiology of sudden cardiac death. Death can sometimes be prevented by the implantation of a defibrillator (ICD). When an out-of-hospital cardiac arrest (OHCA) has occurred some circumstances characterize those who survive. Medication used to treat disease is not always harmless. Methods: The population in the Swedish Cardiac Arrest Register was used to characterize the survivors, and for the recently added drugs, before an OHCA, used together with the Swedish Prescribed Drug Register. The outcome of all consecutive acute myocardial infarction patients during 21 month time at Sahlgrenska University Hospital was investigated to determine if a simple echocardiographic criterion could identify the patients that would die of arrhythmia during two years after the myocardial infarction. Thirty patients with an implanted defibrillator were tested with Transcutaneous Electrical Nerve Stimulation (TENS) to determine the risk of electrical interference with the ICD. Results: The echocardiographic criterion of an ejection fraction ≤30% alone, found only three of the patients who died of presumed arrhythmia and only one of them would have been implanted with an ICD in clinical practice. Six patients who died of presumed arrhythmia had a better ejection fraction. The TENS interfered with 16/30 ICDs. Among survivors of OHCA 20% were from the group found in a non-shockable rhythm and the majority was not reached by the ambulance within five minutes. Recently added drugs before OHCA were most often prescribed for infectious, respiratory and neuro-psychological diseases. 16.2% of the OCHA victims had recently claimed a drug from the” qtdrugs.org” lists .Conclusion: Better criteria or combinations are needed to identify the patients that would benefit from an ICD on a primary prevention indication after myocardial infarction. The TENS device cannot be recommended to be used simultaneously with an ICD and protocols for testing other implantable devices to be used together with an ICD are warranted. New drugs frequently claimed before OHCA should be further investigated and the OHCA victims found in non-shockable rhythm need more attention. The delay-time for ambulance arrival to the OHCA victim is long. Keywords: Cardiac arrest, ICD, ventricular arrhythmia ISBN: 978-91-628-8389-8
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