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- Alkhede, Maria, 1961-, et al.
(författare)
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Preschool children’s discernment of different forms of numbers
- 2018
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- The aim of this study is to describe in what way preschool activities contribute to the development of children's knowledge of different forms of numbers; symbols, ordinal and cardinal. Video -recordings from three different groups of preschool children age d 3 to 5 years old have been analyzed based on variation theory (Marton, 2015) to describe the children’s discernment of numbers. The activities were planned and enacted by preschool teachers. The teachers’ intentions were to teach the children numerosity (Hannula - Sormunen et.al., 2016). The activities offered learning possibilities during the activities, e.g. to sort digits by magnitude, value or just to match symbols. The video -recordings were analyzed to capture what as- pects of the numbers the children were offered to discern, and what aspects were not offered to discern during the different activities. Simultaneous discernment of numbers in different forms are important for children’s future mathematical performance (Hannul- Sormunen et.al., 2015). The fi ndings unveil the teachers’ challenges to design preschool activities offering children simultaneously discernment of num- bers’ different forms. The activities mainly make the children discern numbers as symbols to match or as magnitude, while the cardinal form occurred only to a limited extent.
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| 2. |
- Andersson, Ellen, et al.
(författare)
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GRACE: Geriatric patients tReated with Avastin in CRC multiple linEs
- 2017
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Ingår i: Clinical Practice. - : Future Medicine. - 2044-9038 .- 2044-9046. ; 14:3, s. 175-182
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Tidskriftsartikel (refereegranskat)abstract
- Continuous treatment with bevacizumab in elderly patients with mCRC: A phase IV prospective, open-label, single-arm trial to evaluate outcomes and safety with continuous bevacizumab treatment in combination with chemotherapy over disease progression.
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| 3. |
- Bonnesen, Trine G., et al.
(författare)
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Disease-specific Hospitalizations among 5-Year Survivors of Hepatoblastoma : A Nordic Population-based Cohort Study
- 2019
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Ingår i: Journal of Pediatric Hematology/Oncology. - 1077-4114. ; 41:3, s. 181-186
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: The long-term risk of somatic disease in hepatoblastoma survivors has not been thoroughly evaluated in previous studies. In this population-based study of 86 five-year HB survivors, we used inpatient registers to evaluate the risk for a range of somatic diseases.Methods: In total, 86 five-year survivors of hepatoblastoma were identified in the Nordic cancer registries from 1964 to 2008 and 152,231 population comparisons were selected. Study subjects were followed in national hospital registries for somatic disease classified into 12 main diagnostic groups. Standardized hospitalization rate ratios (RRs) and absolute excess risks were calculated.Results: After a median follow-up of 11 years, 35 of the 86 five-year hepatoblastoma survivors had been hospitalized with a total of 69 hospitalizations, resulting in an RR of 2.7 (95% confidence interval [CI], 2.2-3.5) and an overall absolute excess risk of 4.2 per 100 person-years. Highest risk was seen for benign neoplasms (RR=16) with 6 hospitalizations for benign neoplasms in the colon and one in rectum.Conclusions: The pattern of hospitalizations found in this first comprehensive follow-up of hepatoblastoma survivors seems reassuring. Less than 50% of the 5-year survivors had been hospitalized and often for diseases that were not severe or life-threatening.
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| 4. |
- Bonnesen, Trine Gade, et al.
(författare)
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Liver diseases in Adult Life after Childhood Cancer in Scandinavia (ALiCCS) : A population-based cohort study of 32,839 one-year survivors
- 2018
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Ingår i: International Journal of Cancer. - : Wiley. - 0020-7136. ; 142:4, s. 702-708
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Tidskriftsartikel (refereegranskat)abstract
- Information on late onset liver complications after childhood cancer is scarce. To ensure an appropriate follow-up of childhood cancer survivors and reducing late liver complications, the need for comprehensive and accurate information is presented. We evaluate the risk of liver diseases in a large childhood cancer survivor cohort. We included all 1-year survivors of childhood cancer treated in the five Nordic countries. A Cox proportional hazards model was used to estimate hospitalisation rate (hazard) ratios (HRs) for each liver outcome according to type of cancer. We used the risk among survivors of central nervous system tumour as internal reference. With a median follow-up time of 10 years, 659 (2%) survivors had been hospitalised at least once for a liver disease. The risk for hospitalisation for any liver disease was high after hepatic tumour (HR = 6.9) and leukaemia (HR = 1.7). The Danish sub-cohort of leukaemia treated with haematopoietic stem cell transplantation had a substantially higher risk for hospitalisation for all liver diseases combined (HR = 3.8). Viral hepatitis accounted for 286 of 659 hospitalisations corresponding to 43% of all survivors hospitalised for liver disease. The 20-year cumulative risk of viral hepatitis was 1.8% for survivors diagnosed with cancer before 1990 but only 0.3% for those diagnosed after 1990. The risk of liver disease was low but significantly increased among survivors of hepatic tumours and leukaemia. Further studies with focus on the different treatment modalities are needed to further strengthen the prevention of treatment-induced late liver complications.
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| 5. |
- Bonnesen, Trine Gade, et al.
(författare)
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Long-term risk of renal and urinary tract diseases in childhood cancer survivors : A population-based cohort study
- 2016
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Ingår i: European Journal of Cancer. - : Elsevier BV. - 0959-8049. ; 64, s. 52-61
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Tidskriftsartikel (refereegranskat)abstract
- Background Childhood cancer has been associated with long-term risk of urinary tract diseases, but risk patterns remain to be comprehensively investigated. We analysed the lifetime risk of urinary tract diseases in survivors of childhood cancer in the Nordic countries. Methods We identified 32,519 one-year survivors of childhood cancer diagnosed since the 1940s and 1950s in the five Nordic cancer registries and selected 211,156 population comparisons of a corresponding age, sex, and country of residence from the national population registries. To obtain information on all first-time hospitalizations for a urinary tract disease, we linked all study subjects to the national hospital registry of each country. Relative risks (RRs) and absolute excess risks (AERs) and associated 95% confidence intervals (CIs) for urinary tract diseases among cancer survivors were calculated with the appropriate morbidity rates among comparisons as reference. Results We observed 1645 childhood cancer survivors ever hospitalized for urinary tract disease yielding an RR of 2.5 (95% CI 2.4-2.7) and an AER of 229 (95% CI 210-248) per 100,000 person-years. The cumulative risk at age 60 was 22% in cancer survivors and 10% in comparisons. Infections of the urinary system and chronic kidney disease showed the highest excess risks, whereas survivors of neuroblastoma, hepatic and renal tumours experienced the highest RRs. Conclusion Survivors of childhood cancer had an excess risk of urinary tract diseases and for most diseases the risk remained elevated throughout life. The highest risks occurred following therapy of childhood abdominal tumours.
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| 6. |
- Borgestig, Maria, et al.
(författare)
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Nya möjligheter i vardagen – ögonstyrd dator för personer med omfattande funktionsnedsättning
- 2019
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Konferensbidrag (refereegranskat)abstract
- Bakgrund/SyfteÖgonstyrd dator har potential att ge nya möjligheter för personer med omfattande funktionsnedsättning och kan vara det enda sättet för dessa att på egen hand utföra vardagsaktiviteter. Syftet med symposiet är att delge forskningsresultat och kliniska tillämpningar kring användning av ögonstyrd dator i vardagen.Metod/TillvägagångssättSymposiet består av korta presentationer (10-15 min) av fyra presentatörer: forskare, yrkesverksam arbetsterapeut samt logoped inom området. Användning av ögonstyrd dator kommer rapporteras utifrån; en interventionsstudie med longitudinell design (10 barn, omfattande funktionsnedsättning), två kvalitativa studier (föräldrars och lärares perspektiv), fallstudier med litet barn (9 månader) respektive ungdom med Rett syndrom, nationell enkätundersökning (171 användare, 4-81 år). Utvecklingsprojekt om upplägg i datorn för att erbjuda färdiga lösningar kommer också rapporteras.Resultat/Preliminärt resultatInterventionen visar att ögonstyrd dator är användbart som hjälpmedel för barn i olika åldrar och med olika diagnoser. Utifrån föräldrars och lärares perspektiv kan barnen påverka sin situation genom ögonstyrd dator vilket ger hopp inför framtiden. Fallstudierna kommer rapportera nyttan med ögonstyrd dator som tidig intervention för att gradvis lära sig utföra aktiviteter samt hur aktivt deltagande i vardagen kan påverkas. Enkätundersökningen visar på olika aspekter av användbarheten med ögonstyrd dator för personer med funktionsnedsättning. Färdiga upplägg för kommunikation, fritidsaktiviteter och lärandesituationer kommer också presenteras.Slutsats/Praktisk tillämpningSymposiet ger fördjupade kunskaper och förståelse för hur ögonstyrd dator kan bidra till och används för lek, kommunikation, skol- och arbetsuppgifter av personer med omfattande funktionsnedsättning.Deltagare på symposiet kommer få delge sina erfarenheter och delta i diskussion om hur forskningsresultat kan bidra till förståelse, möjligheter och tillämpning av ögonstyrd dator.
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| 7. |
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| 10. |
- Holmqvist, Anna
(författare)
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Integritet på undantag? : En studie av barns röst i patientlagen och patientorganisationer
- 2019
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis explores discourses regarding children’s voice, in the Swedish Patient Act, as well as in Swedish patient organizations. In the Patient Act, children’s rights as patients are construed on the basis of custodians’ parental rights and the assumption that patients are competent and autonomous adults. The child is given an object position, weaker than an adult patient and subordinated to parents’ authority. Consequently, the integrity of the child is not absolute, as it is construed through an autonomy discourse and a family discourse which set boundaries for the child´s voice in the Patient Act. The family discourse combined with a mass movement discourse form the prerequisits for children’s voice in the context of patient organizations. As a consequence, patient organizations do not act as voice in relation to children’s rights as patients, in the Patient Act. Rather, interviews with representatives of patient organizations show that the parents act as voice having a child in need of health care. The position of children in the organizationsis ambiguous and, rather than having a voice of their own, children can be used in advertising campaigns to attract funding, expressing the voice of the organization. When children are used in this way by organizations, children’s integrity seem to be negotiable. The thesis shows that in both the Patient Act and the patient organizations, the integrity of the child is questioned. Children seem to be regarded as imperfect rights-holders and as imperfect members of society.This perception of the child is traced to dominant ethical perspectives from which children’s human rights have emerged. Drawing on current academic debates, analternative approach to these prevailing ethical perspectives is suggested. Instead of making rights conditional upon presumed autonomy and adulthood, rights can be perceived as relational and expressions of the mutual interdependence of humans, regardless of age and maturity. If rights are seen in this way, with children being understood not as essentially different but differently equal, then the child´s voice can have actual importance.
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