| 1. |
- Elsik, Christine G., et al.
(författare)
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The Genome Sequence of Taurine Cattle : A Window to Ruminant Biology and Evolution
- 2009
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 324:5926, s. 522-528
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Tidskriftsartikel (refereegranskat)abstract
- To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.
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| 2. |
- Anisi, David A., 1977-
(författare)
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Online trajectory planning and observer based control
- 2006
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The main body of this thesis consists of four appended papers. The first two consider different aspects of the trajectory planning problem, while the last two deal with observer design for mobile robotic and Euler-Lagrange systems respectively. The first paper addresses the problem of designing a real time, high performance trajectory planner for aerial vehicles. The main contribution is two-fold. Firstly, by augmenting a novel safety maneuver at the end of the planned trajectory, this paper extends previous results by having provable safety properties in a 3D setting. Secondly, assuming initial feasibility, the planning method is shown to have finite time task completion. Moreover, in the second part of the paper, the problem of simultaneous arrival of multiple aerial vehicles is considered. By using a time-scale separation principle, one is able to adopt standard Laplacian control to this consensus problem, which is neither unconstrained, nor first order. Direct methods for trajectory optimization are traditionally based on a priori temporal discretization and collocation methods. In the second paper, the problem of adaptive node distribution is formulated as a constrained optimization problem, which is to be included in the underlying nonlinear mathematical programming problem. The benefits of utilizing the suggested method for online trajectory optimization are illustrated by a missile guidance example. In the third paper, the problem of active observer design for an important class of non-uniformly observable systems, namely mobile robotics systems, is considered. The set of feasible configurations and the set of output flow equivalent states are defined. It is shown that the inter-relation between these two sets may serve as the basis for design of active observers. The proposed observer design methodology is illustrated by considering a unicycle robot model, equipped with a set of range-measuring sensors. Finally, in the fourth paper, a geometrically intrinsic observer for Euler-Lagrange systems is defined and analyzed. This observer is a generalization of the observer recently proposed by Aghannan and Rouchon. Their contractivity result is reproduced and complemented by a proof that the region of contraction is infinitely thin. However, assuming a priori bounds on the velocities, convergence of the observer is shown by means of Lyapunov's direct method in the case of configuration manifolds with constant curvature.
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| 3. |
- Cheng, Daizhan, et al.
(författare)
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An extension of LaSalle's invariance principle and its application to multi-agent consensus
- 2008
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Ingår i: IEEE Transactions on Automatic Control. - : Institute of Electrical and Electronics Engineers (IEEE). - 0018-9286 .- 1558-2523. ; 53:7, s. 1765-1770
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Tidskriftsartikel (refereegranskat)abstract
- In the paper, an extension of LaSalle's Invariance Principle to a class of switched linear systems is studied. One of the motivations is the consensus problem in multi-agent systems. Unlike most existing results in which each switching mode in the system needs to be asymptotically stable, this paper allows that the switching modes are only Lyapunov stable. Under certain ergodicity assumptions, an extension of LaSalle's Invariance Principle for global asymptotic stability is obtained. Then it is used to solve the consensus reaching problem of certain multi-agent systems in which each agent is modeled by a double integrator, and the associated interaction graph is switching and is assumed to be only jointly connected.
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| 4. |
- Cheng, D., et al.
(författare)
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Set stability and controllability for switched non-homogeneous linear systems
- 2007
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Ingår i: 2006 Chinese Control Conference Proceedings, CCC 2006. - : IEEE. - 7810778021 - 9787810778022 ; , s. 2171-2176
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Konferensbidrag (refereegranskat)abstract
- In this paper we consider some control problems of switched non-homogeneous linear systems. First, the set stability of switched non-homogeneous linear systems is considered. It is proved that as the linear parts have a common quadratic Lyapunov function the set stability is assured. The problem of searching smallest attracting set is then considered. Then we assume the switching law is controllable and investigate the controllability condition within the attracting region. Finally, we consider the aggregation and the control of aggregation of flocking behavior. Particularly, the results obtained are implemented to analyzing and manipulating of a group of mobile robots.
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| 5. |
- Cheng, D., et al.
(författare)
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Stabilization of switched linear systems via LaSalle's invariance principle
- 2008
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Konferensbidrag (refereegranskat)abstract
- This paper considers the stability of switched linear systems. Assume a common weak quadratic Lyapunov function exists and the switches satisfy certain ergodic property, we investigate two extensions of LaSalle's invariance principle. Unlike most existing results, the systems we investigated may have switching modes, which are not asymptotically stable. An application to the consensus of multi-agent systems is presented.
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| 6. |
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| 7. |
- Klionsky, Daniel J., et al.
(författare)
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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
- 2008
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Ingår i: Autophagy. - : Landes Bioscience. - 1554-8627 .- 1554-8635. ; 4:2, s. 151-175
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Forskningsöversikt (refereegranskat)abstract
- Research in autophagy continues to accelerate,1 and as a result many new scientists are entering the field. Accordingly, it is important to establish a standard set of criteria for monitoring macroautophagy in different organisms. Recent reviews have described the range of assays that have been used for this purpose.2,3 There are many useful and convenient methods that can be used to monitor macroautophagy in yeast, but relatively few in other model systems, and there is much confusion regarding acceptable methods to measure macroautophagy in higher eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers of autophagosomes versus those that measure flux through the autophagy pathway; thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from fully functional autophagy that includes delivery to, and degradation within, lysosomes (in most higher eukaryotes) or the vacuole (in plants and fungi). Here, we present a set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes. This set of guidelines is not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to verify an autophagic response.
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| 8. |
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| 9. |
- Nabiollahi, Nabi, 1983, et al.
(författare)
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FEM Simulation of Bimodal and Trimodal Thermally Conductive Adhesives
- 2009
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Ingår i: 2009 9th IEEE Conference on Nanotechnology, IEEE NANO 2009; Genoa; Italy; 26 July 2009 through 30 July 2009. - 9789810836948 ; , s. 422-425
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Konferensbidrag (refereegranskat)abstract
- A simulation with combination of a finite element analysis of Thermally Conductive Adhesive and contact resistance modeling has been presented. Using ANSYS and MATLAB software thermal conductivity and electrical resistivity of Conductive Adhesives with Ag filler and Epoxy matrix has been calculated. Thermally Conductive Adhesives are used as a thermal interface material to provide a better conduction and heat transfer between two surfaces. The results show that the conductivity dependency is relatively high for different filler shape and alignment. Discussed models are bimodal, Ag flakes and Ag spherical micro particles and trimodal with Multi-WallCNT nano particles.
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| 10. |
- Ni, W., et al.
(författare)
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Minimum dwell time for stability and stabilization of switched linear systems
- 2008
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Ingår i: Proc. World Congr. Intelligent Control Autom. WCICA. - 9781424421145 ; , s. 4103-4108
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Konferensbidrag (refereegranskat)abstract
- In this paper, the problem of minimum dwell time for the stability and stabilization of switched linear systems is considered. First, using the method of multiple Lyapunov functions, we obtain an estimate for the minimum dwell time(MDT), which assures the exponential stability of switched linear systems. Using the stability result obtained for free system, we then investigate the problem of MDT for stabilization of switched linear control system subject to input constraints. Under certain conditions the exponential stabilization can be achieved by using controls with restricted amplitudes as long as the switching laws satisfy the MDT time requirement. An illustrative example is presented to show the validity of the results.
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