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> (2024) >
Response strategies...
Response strategies and biological applications of organic fluorescent thermometry: cell- and mitochondrion-level detection
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- Li, Shuai (författare)
- Xiamen Univ, Peoples R China
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- Li, Yaoxuan (författare)
- Shanxi Med Univ, Peoples R China
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- Zhang, Shiji (författare)
- Xiamen Univ, Peoples R China
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- Fang, Haixiao (författare)
- Xiamen Univ, Peoples R China; Future Display Inst Xiamen, Peoples R China
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- Huang, Ze (författare)
- Xiamen Univ, Peoples R China
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- Zhang, Duoteng (författare)
- Xiamen Univ, Peoples R China
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- Ding, Aixiang (författare)
- Xiamen Univ, Peoples R China
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- Uvdal, Kajsa (författare)
- Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten
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- Hu, Zhang-Jun (författare)
- Linköpings universitet,Molekylär ytfysik och nanovetenskap,Tekniska fakulteten
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- Huang, Kai (författare)
- Future Display Inst Xiamen, Peoples R China
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- Li, Lin (författare)
- Xiamen Univ, Peoples R China; Future Display Inst Xiamen, Peoples R China
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(creator_code:org_t)
- 2024
- 2024
- Engelska.
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Ingår i: Analytical Methods. - : ROYAL SOC CHEMISTRY. - 1759-9660 .- 1759-9679.
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Temperature homeostasis is critical for cells to perform their physiological functions. Among the diverse methods for temperature detection, fluorescent temperature probes stand out as a proven and effective tool, especially for monitoring temperature in cells and suborganelles, with a specific emphasis on mitochondria. The utilization of these probes provides a new opportunity to enhance our understanding of the mechanisms and interconnections underlying various physiological activities related to temperature homeostasis. However, the complexity and variability of cells and suborganelles necessitate fluorescent temperature probes with high resolution and sensitivity. To meet the demanding requirements for intracellular/subcellular temperature detection, several strategies have been developed, offering a range of options to address this challenge. This review examines four fundamental temperature-response strategies employed by small molecule and polymer probes, including intramolecular rotation, polarity sensitivity, Forster resonance energy transfer, and structural changes. The primary emphasis was placed on elucidating molecular design and biological applications specific to each type of probe. Furthermore, this review provides an insightful discussion on factors that may affect fluorescent thermometry, providing valuable perspectives for future development in the field. Finally, the review concludes by presenting cutting-edge response strategies and research insights for mitigating biases in temperature sensing. In this review, we primarily summarized four temperature-response strategies. Then, we further analyzed the chemical modifications and biological applications of the probes. Finally, we have provided a prospective on the future development of probes.
Ämnesord
- NATURVETENSKAP -- Kemi -- Analytisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Analytical Chemistry (hsv//eng)
Publikations- och innehållstyp
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Till lärosätets databas
- Av författaren/redakt...
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Li, Shuai
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Li, Yaoxuan
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Zhang, Shiji
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Fang, Haixiao
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Huang, Ze
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Zhang, Duoteng
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visa fler...
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Ding, Aixiang
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Uvdal, Kajsa
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Hu, Zhang-Jun
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Huang, Kai
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Li, Lin
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- Om ämnet
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- NATURVETENSKAP
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NATURVETENSKAP
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och Kemi
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och Analytisk kemi
- Artiklar i publikationen
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Analytical Metho ...
- Av lärosätet
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Linköpings universitet