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Träfflista för sökning "WFRF:(Hursti Timo) srt2:(2000-2004)"

Sökning: WFRF:(Hursti Timo) > (2000-2004)

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1.
  • Björklund, Fredrik, et al. (författare)
  • A Swedish translation and validation of the Disgust Scale: A measure of disgust sensitivity
  • 2004
  • Ingår i: Scandinavian Journal of Psychology. - : Wiley. - 1467-9450 .- 0036-5564. ; 45:4, s. 279-284
  • Tidskriftsartikel (refereegranskat)abstract
    • The psychometric properties of a Swedish version of Haidt, McCauley and Rozin's (1994) Disgust Scale were studied. Confirmatory factor analysis of the original model with eight factors (food, animals, body products, sex, body envelope violations, death, hygiene, and magic) provided satisfactory fit to the data (N= 280), significantly better than to the alternative one-factor and five-factor models. As in the US version women scored significantly higher than men. Positive correlations with measures of food neophobia (r= 0.30, p < 0.0001) and nausea frequency (r(s)= 0.28, p < 0.001) indicate convergent validity. In a separate study (N= 30) a behavioral measure of the willingness to touch, hold, and taste disgusting food objects correlated negatively with the Disgust Scale (r=-0.46, p < 0.01), indicating criterion-related validity.
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2.
  • Lundström, Staffan, et al. (författare)
  • Aspects of delayed chemotherapy-induced nausea : Dexamethasone and adrenal response patterns in patients and healthy volunteers
  • 2000
  • Ingår i: Supportive Care in Cancer. - : Springer. - 0941-4355 .- 1433-7339. ; 8:5, s. 431-434
  • Tidskriftsartikel (refereegranskat)abstract
    • Delayed chemotherapy-induced nausea is still a clinical problem, and the underlying mechanisms are poorly understood. Previous studies have suggested that corticosteroids are involved, although the mechanisms by which corticosteroids exert their anti-emetic effect are largely unknown. We have previously found impaired control of delayed nausea after injection of dexamethasone. The possibility of differences in the recovery of the hypothalamic-pituitary-adrenal (HPA) axis after injection of dexamethasone was investigated in patients (n = 5) with gynaecological cancer being treated with platinum-based chemotherapy and in healthy female volunteers (n = 10). Urinary free cortisol was used to assess the levels of endogenous cortisol. Results showed that in both patients and controls injections of dexamethasone led to a significant decline in endogenous cortisol levels in 24 h and a subsequent significant recovery in the next 24 h. We conclude that the recovery of the HPA axis is rapid after a single dose of dexamethasone in patients and controls. The absence of an abnormal response pattern in patients makes it probable that the suppression and recovery of the HPA axis after injection of dexamethasone does not influence the corticosteroid-induced rebound effect on delayed platinum-induced nausea.
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