| 1. |
- Gente-Lidholm, Anette, et al.
(författare)
-
Loss of patch-test reaction to aluminium years after vaccination with aluminium adjuvants in a population of 76.000 children.
- 2010
-
Ingår i: Contact Dermatitis. - 0105-1873 .- 1600-0536.
-
Konferensbidrag (refereegranskat)abstract
- During trials of aluminium adsorbed diphtheria–rntetanus/acellular pertussis vaccines from a single producer,rnpersistent intensely itching nodules at the vaccination site werernobserved in an unexpectedly high frequency (about 1%) in thernstudy area around Gothenburg, Sweden. All afflicted childrenrnwere offered patch testing for aluminium. Among the childrenrnsensitisation to aluminium was demonstrated in a highrnfrequency (77%). The children demonstrated positive patchrntests for aluminium were offered to repeat the test 5 years later.rnObjectives: To study the clinical course of itching nodules andrncontact allergy to aluminium.rnMethods: Two hundred and fifty children with itching nodulesrnat the injection site after vaccination with aluminium adsorbedrndiphtheria–tetanus/acellular pertussis vaccines that earlier hadrnshown a positive patch test reaction to aluminium, wherernrepeated the patch test more than 5 years later. Thernchildren were patch tested in the same way as beforernwith aluminiumchloridehexahydrate 2% in petrolatumrn(Chemotechnique Diagnostics, Sweden) in plastic chambersrnfrom the same manufacturer, and also with an empty FinnrnChamber (Epitest, Finland). The tests were read on day threernusing the ICDRG’s criteria.rnResults: Among the 250 children tested, approximately 75% hadrnno remaining positive patch test to aluminium. Only a few of thernchildren presented still itching nodules.rnConclusion: Three out of four children with earlier shownrncontact allergy to aluminium had lost their patch testrnreactivity 5 years later.
|
|
| 2. |
- Inerot, Annica, 1949, et al.
(författare)
-
LOCAL ITCHING AND SWELLING THREE DAYS AFTER TATTOOING WITH YELLOW AND GREEN COLORS IN A YOUNG WOMEN, KNOWN TO BE CONTACT ALLERGIC TO ALUMINIUM
- 2013
-
Ingår i: European Congress on Tattoo and Pigment Research, Nov 13-14, 2013, Copenhagen.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Aim: To highlight the risk of local contact dermatitis from aluminum in a tattoo, a case report. Method: Observing an 18 years of age women seeking medical care three days after having tattooed a flower decoration on her right arm. Background: At the age of 10 she had problems with itching and eczema on her upper left arm after vaccination and in her armpits, when using deodorants. A dermatologist referred her to a patch test clinic on the suspicion of contact allergy to aluminum. The patch test showed a strong reaction (+++) to aluminum chloride hexahydrate 2, 0 % in petrolatum. Eight years later – on a Monday – she asked a tattoo parlor to make a four-colored decoration of her right arm. She asked them before if there were any aluminum in the tattoo and was reassured that this was not the case. The tattooing was done in black, red, yellow and green colors. On Thursday she had severe itching and swelling where there was yellow and green tattooing. She had no reaction at all where there were black or red colors. She was recommended local steroid application. Results: The itching continued for around a year. The yellow color was analysed and contained 960 microgram aluminum per gram. Conclusions: Individuals with an earlier subcutaneous itching nodule from vaccination could get long lasting contact dermatitis after a tattoo.
|
|
| 3. |
- Isaksson, Marléne, et al.
(författare)
-
Multicentre patch testing with a resol resin based on phenol and formaldehyde
- 2011
-
Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 65:1, s. 34-37
-
Tidskriftsartikel (refereegranskat)abstract
- Background. Contact allergy to phenol-formaldehyde resins (PFRs) based on phenol and formaldehyde is not detected by a p-tertiary-butylphenol-formaldehyde resin (PTBP-FR) included in most baseline patch test series. Objectives. To investigate the rate of contact allergy to PFR-2 (a mixture of monomers and dimers from a resol resin based on phenol and formaldehyde) in a Swedish population, and to investigate associated simultaneous allergic reactions. Methods. Five centres representing the Swedish Contact Dermatitis Research Group included PFR-2 in their patch test baseline series for a period of 1.5 years. Results. Of 2504 patients tested, 27 (1.1%) reacted to PFR-2. Of those 27 individuals, 2 had a positive reaction to formaldehyde and 2 to PTBP-FR. Simultaneous allergic reactions were noted to colophonium in 6, to Myroxylon pereirae in 14, and to fragrance mix I in 15. Conclusions. The contact allergy frequency in the tested population (1.1%) merits its inclusion in the Swedish baseline series and possibly also in other baseline series. Simultaneous allergic reactions were noted to colophonium, M. pereirae, and fragrance mix I.
|
|
| 4. |
- Isaksson, Marléne, et al.
(författare)
-
Multicentre patch testing with compositae mix by the Swedish contact dermatitis research group
- 2011
-
Ingår i: Acta Dermato-Venereologica. - : Society for Publication of Acta Dermato-Venereologica. - 0001-5555 .- 1651-2057. ; 91:3, s. 295-298
-
Tidskriftsartikel (refereegranskat)abstract
- Sesquiterpene lactone mix detects contact allergy to these compounds present in the plant family Asteraceae. This marker is present in many baseline series. An additional marker is Compositae mix, which is not present in many baseline series. To investigate whether this allergen should be inserted into the Swedish baseline series, sex dermatology centres representing the Swedish Contact Dermatitis Research Group included Compositae mix into their baseline series for 1.5 years. Of 2818 patients tested, 31 (1.1%) reacted to Compositae mix and 26 (0.9%) to Sesquiterpene lactone mix. Active sensitization to Compositae mix was noted in two cases. Only 0.4% of Asteraceae contact allergy cases would have been missed if Compositae mix had not been tested, a frequency too low to merit its inclusion in the baseline series. Due to obvious geographical differences in frequency in frequency of simultaneous allergic reactions to Compositae mix and Sesquiterpene lactone mix, the question as to whether specific baseline series (including Compositae mix or not as a "tail" substance) should be used in the different centres must be addressed. Another option could be to remove Sesquiterpene lactone mix from the baseline series and substitute it with Compositae mix.
|
|
| 5. |
|
|
| 6. |
|
|
| 7. |
- Lidholm, Anette Gente, et al.
(författare)
-
Unexpected loss of contact allergy to aluminium induced by vaccine
- 2013
-
Ingår i: Contact Dermatitis. - : John Wiley & Sons. - 0105-1873 .- 1600-0536. ; 68:5, s. 286-292
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND:In studies in Gothenburg, Sweden, in the 1990s of an aluminium hydroxide-adsorbed pertussis toxoid vaccine, 745 of ~76 000 vaccinated children developed long-lasting itchy subcutaneous nodules at the vaccination site. Of 495 children with itchy nodules patch tested for aluminium allergy, 376 (76%) were positive.OBJECTIVES:To study the prognosis of the vaccine-induced aluminium allergy.PATIENTS AND METHODS:Two hundred and forty-one children with demonstrated aluminium allergy in the previous study were patch tested again 5-9 years after the initial test, with the same procedure as used previously.RESULTS:Contact allergy to aluminium was no longer demonstrable in 186 of the retested 241 children (77%). A negative test result was more common in children who no longer had itching at the vaccination site; it was also related to the age of the child, the time after the first aluminium-adsorbed vaccine dose, and the strength of the reaction in the first test.CONCLUSIONS:Patch test reactivity to aluminium seems to disappear or weaken with time.
|
|
| 8. |
- Tammela, Monica, et al.
(författare)
-
Patch testing with own cosmetics : a prospective study of testing and reporting of adverse effects to the Swedish Medical Products Agency
- 2012
-
Ingår i: Contact Dermatitis. - Hoboken, USA : Wiley-Blackwell. - 0105-1873 .- 1600-0536. ; 67:1, s. 42-46
-
Tidskriftsartikel (refereegranskat)abstract
- Background: The Swedish Medical Products Agency (MPA) provides a voluntary reporting system for adverse reactions to cosmetics. However, the reporting is sparse, and the products involved are sometimes difficult to identify.Objectives: To investigate how often patients referred for patch testing were tested with the cosmetic products that they had been using themselves, and to improve the reporting to the MPA by the use of photographic documentation of product labels.Patients and methods: Consecutive patients at five dermatology departments who were patch tested with their own cosmetics were included. Reports including protocols of positive patch test results for the patients' own cosmetics and photographs/photocopies of product labels were sent to the MPA. Results. Three hundred and sixteen of 948 patients (33%) were tested with their own cosmetics, and 15% of these tested positive with one or more products. The number of reports was more than three times higher than in corresponding periods in earlier years. For 79% of the products, photographs/photocopies of the containers were submitted, and for 30%, batch numbers were submitted.Conclusions: For a substantial number of patients, their own cosmetics were suspected of causing adverse reactions and were therefore tested. During the study, the number of reports to the MPA tripled, and the relevant products were easier to identify.
|
|
| 9. |
|
|
