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25-Hydroxyvitamin D...
25-Hydroxyvitamin D reference percentiles and the role of their determinants among European children and adolescents
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- Wolters, M. (författare)
- Leibniz Institute for Prevention Research and Epidemiology-BIPS, Bremen, Germany
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- Intemann, T. (författare)
- Leibniz Institute for Prevention Research and Epidemiology-BIPS, Bremen, Germany
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- Russo, P. (författare)
- Institute of Food Sciences, National Research Council, Avellino, Italy
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- Moreno, L. A. (författare)
- GENUD (Growth, Exercise, Nutrition and Development) Research Group, Faculty of Health Sciences, Universidad de Zaragoza, Instituto Agroalimentario de Aragón (IA2), Instituto de Investigación Sanitaria Aragón (IIS Aragón), Zaragoza, Spain and Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERObn), Instituto de Salud Carlos III, Madrid, Spain
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- Molnar, D. (författare)
- Department of Pediatrics, Medical School, University of Pécs, Hungary
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- Veidebaum, T. (författare)
- National Institute for Health Development, Estonian Centre of Behavioral and Health Sciences, Tallinn, Estonia
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- Tornaritis, M. (författare)
- Research and Education Institute of Child Health, Strovolos, Cyprus
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- De Henauw, S. (författare)
- Department of Public Health and Primary Care, Ghent University, Belgium
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- Eiben, Gabriele, 1960 (författare)
- Högskolan i Skövde,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Institutionen för hälsovetenskaper,Forskningsmiljön hälsa, hållbarhet och digitalisering,Department of Public Health and Community Medicine, University of Gothenburg, Sweden,Medborgarcentrerad hälsa MeCH, Research on Citizen Centered Health, University of Skövde (Reacch US)
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- Ahrens, W. (författare)
- Leibniz Institute for Prevention Research and Epidemiology-BIPS, Bremen, Germany ; Institute of Statistics, Faculty of Mathematics and Computer Science, University of Bremen, Germany
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- Floegel, A. (författare)
- Leibniz Institute for Prevention Research and Epidemiology-BIPS, Bremen, Germany
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(creator_code:org_t)
- 2021-07-23
- 2022
- Engelska.
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Ingår i: European Journal of Clinical Nutrition. - : Springer Science and Business Media LLC. - 0954-3007 .- 1476-5640. ; 76, s. 564-573
- Relaterad länk:
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https://www.nature.c...
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https://doi.org/10.1...
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https://his.diva-por... (primary) (Raw object)
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background/objectives To provide age- and sex-specific percentile curves of serum 25-hydroxyvitamin D (25(OH)D) by determinants from 3-<15 year-old European children, and to analyse how modifiable determinants influence 25(OH)D. Subjects/methods Serum samples were collected from children of eight European countries participating in the multicenter IDEFICS/I.Family cohort studies. Serum 25(OH)D concentrations were analysed in a central lab by a chemiluminescence assay and the values from 2171 children (N = 3606 measurements) were used to estimate percentile curves using the generalized additive model for location, scale and shape. The association of 25(OH)D with time spent outdoors was investigated considering sex, age, country, parental education, BMI z score, UV radiation, and dietary vitamin D in regressions models. Results The age- and sex-specific 5th and 95th percentiles of 25(OH)D ranged from 16.5 to 73.3 and 20.8 to 79.3 nmol/l in girls and boys, respectively. A total of 63% had deficient (<50 nmol/l), 33% insufficient (50-<75 nmol/l) and 3% sufficient (>= 75 nmol/l) levels. 25(OH)D increased with increasing UV radiation, time spent outdoors, and vitamin D intake and slightly decreased with increasing BMI z score and age. The odds ratio (OR) for a non-deficient 25(OH)D status (reference category: deficient status) by one additional hour spent outdoors was 1.21, 95% CI [1.12-1.31], i.e., children who spent one more hour per day outdoors than other children had a 21% higher chance of a non-deficient than a deficient status. Conclusion A majority of children suffer from deficient 25(OH)D. UV radiation, outdoor time, and dietary vitamin D are important determinants of 25(OH)D.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Nyckelord
- vitamin-d status
- parathyroid-hormone concentrations
- body-mass index
- d
- deficiency
- young-children
- life-style
- health
- overweight
- prevention
- society
- Nutrition & Dietetics
- Research on Citizen Centered Health, University of Skövde (Reacch US)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Wolters, M.
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Intemann, T.
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Russo, P.
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Moreno, L. A.
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Molnar, D.
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Veidebaum, T.
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Tornaritis, M.
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De Henauw, S.
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Eiben, Gabriele, ...
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Ahrens, W.
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Floegel, A.
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Näringslära
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Pediatrik
- Artiklar i publikationen
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European Journal ...
- Av lärosätet
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Göteborgs universitet
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Högskolan i Skövde