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- Dahlin, Jakob, et al.
(författare)
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Several cases of undesirable effects caused by methacrylate ultraviolet-curing nail polish for non-professional use
- 2016
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Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 75:3, s. 151-156
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundUltraviolet (UV)-curing nail polishes based on acrylates or methacrylates are currently also available for non-professional use. The Swedish Medical Products Agency recently prohibited one brand of UV-curing polish, because several consumers reported undesirable effects after using it. ObjectivesTo investigate whether consumers with undesirable effects after using the UV-curing nail polish that was later prohibited were contact allergic to the polish and its individual ingredients. Materials/MethodsEight patients who had reported severe skin reactions after the use of the UV-curing polish were patch tested with two coatings of the nail polish and its ingredients at five dermatology departments in Sweden. ResultsAll patients tested except one showed contact allergic reactions to one or several of the acrylate-based or methacrylate-based ingredients in the nail polish. ConclusionsThe non-professional use of UV-curing nail polishes poses a risk of sensitization from acrylates and methacrylates.
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- Dubnika Hauksson, Inese, et al.
(författare)
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Skin care products containing low concentrations of formaldehyde detected by the chromotropic acid method can not be safely used in formaldehyde-allergic patients.
- 2015
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Ingår i: British Journal of Dermatology. - : Oxford University Press (OUP). - 1365-2133 .- 0007-0963.
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Tidskriftsartikel (refereegranskat)abstract
- Preservatives are widely used to prevent microbial growth both for skin care products and in the industry. Many of them have allergic potential. Allergic contact dermatitis caused by preservatives can often be chronic, probably because it is difficult to suspect contact allergy to these chemicals based on the patient's history only. Formaldehyde is a common cause of contact allergy and has been included in the baseline series since the 1930s (1) . The prevalence of formaldehyde allergy has been reported to be 2-3% in European countries and 8-9% in the US (2) . The use of free formaldehyde as a preservative has decreased and formaldehyde-releasing agents are used instead. Individuals who are allergic to formaldehyde are recommended not only to avoid products preserved with formaldehyde but also products containing formaldehyde-releasers. This article is protected by copyright. All rights reserved.
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- Engfeldt, Malin, et al.
(författare)
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Patch Testing with a New Composition of Mercapto Mix: A Multi-centre Study by the Swedish Contact Dermatitis Research Group
- 2019
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Ingår i: Acta Dermato-Venereologica. - : Medical Journals Sweden AB. - 0001-5555 .- 1651-2057. ; 99:11, s. 960-963
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Tidskriftsartikel (refereegranskat)abstract
- This study investigated whether more patients with contact allergies were detected by patch testing with mercapto mix with a higher concentration of 2-mercaptobenzothiazolinone (MBT) than the commonly used mercapto mix. A total of 3,143 dermatitis patients in 5 Swedish dermatology departments were patch-tested with 3 mercapto test preparations: MBT 2.0% petrolatum (pet.); mercapto mix 2.0% pet.; and mercapto mix 3.5% pet. Positive reactions to these mercapto mixes varied between 0-0.50%, 0-0.93%, and 0-1.4%, respectively, in the 5 centres. Numerically, mercapto mix 3.5% pet. detected all positive patients and more patch-test positive patients than did the 2 other substances, but the difference was not statistically significant. The authors recommend replacing mercapto mix 2.0% pet. in the Swedish baseline series with mercapto mix 3.5% pet., since the latter also detected those patients who would have been missed because MBT 2.0% is not included in the Swedish baseline series.
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- Engfeldt, Malin, et al.
(författare)
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Patch testing with hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) - a multicentre study of the Swedish Contact Dermatitis Research Group
- 2017
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Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 76:1, s. 34-39
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Tidskriftsartikel (refereegranskat)abstract
- Background. In 2014, the fragrance hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) was excluded from the Swedish baseline series. Objectives. To study (i) whether fragrance mix (FM) II with 5% HICC detects more positive reactions than usual FM II with 2.5% HICC, and (ii) the reproducibility of patch testing with HICC. Methods. Two thousand one hundred and eighteen dermatitis patients at five Swedish dermatology departments were consecutively tested with FM II 14% pet., FM II 16.5% pet., and duplicate preparations of HICC 5% pet. Results. Of the patients, 3.2% reacted to FMII 14%, and 1.5% reacted to HICC. Separate testing with HICC detected 0.3% reactions without concomitant reactivity to FM II. FM II with 5% HICC did not give rise to more irritant reactions or signs of active sensitization than FM II with 2.5% HICC. Patch testing with duplicate applications of HICC increased the overall prevalence of HICC contact allergy to 1.9%. Conclusion. FMII with5% HICC does not detect more positive reactions than FMII with 2.5% HICC. Separate testing with HICC does not detect a sufficient proportion of patients who react only to HICC, without concomitant reactions to FMII, to warrant its inclusion in a baseline series.
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- Engfeldt, Malin, et al.
(författare)
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Swedish Experiences From Patch-testing Methylisothiazolinone Separately
- 2015
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Ingår i: Acta Dermato-Venereologica. - : Medical Journals Sweden AB. - 0001-5555 .- 1651-2057. ; 95:6, s. 717-719
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Tidskriftsartikel (refereegranskat)abstract
- The preservative methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) is a well-known sensitiser and present in the Swedish baseline series since the 1980s. The proportions of MCI/MI are 3:1. MI alone has been used as a preservative since less than 10 years. This study was conducted on behalf of the Swedish Contact Dermatitis Research Group to evaluate inclusion of MI in the Swedish baseline series since the preparation of MCI/MI might fail to detect contact-allergic reactions to MI alone. Patients with suspected allergic contact dermatitis at 5 Swedish dermatology departments were consecutively patch-tested with MI 2,000 ppm aq and MCI/MI 200 ppm aq. The number of cases with exclusive contact allergy to MI varied between 0.8-4.2%. In total, 1.9% reacted exclusively to MI and not to MCI/MI. Due to the considerable frequency of contact allergy to MI not traced by MCI/MI, MI 2,000 ppm aq is included in the Swedish baseline series from January 2014. This corresponds to a dose of 60 mu g/cm(2).
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- Eriksson, Thomas, et al.
(författare)
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The use of photos from patch-test reactions on day 7 taken by mobile phones by professional ice hockey players in Sweden investigated for the presence of occupational dermatoses
- 2016
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Ingår i: Contact Dermatitis. - 0105-1873 .- 1600-0536. ; 75:Suppl. 1, s. 39-
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- survey was undertaken in all ice hockey players in 26 professional teams in Sweden representing the two highest divisions. All players answered a questionnaire and the players from six teams, three from each of the two divisions, were patch tested with 72 test preparations in a baseline series supplemented with a series representing the work environment of the players. For practical reasons, the patch testing and test reading on day 3 took place in the arenas of the teams. As a traditional dermatologist reading on day 7 was impossible to perform in all but one team, the players and coaches were asked to use their mobile phones to take photos of the tested backs of the players on day 7 and to send them to the investigative team. In one team a dermatologist reading took place on day 7 independently of the mobile phone photos. In total, 107 players in the six teams were patch tested, and a reading on day 3 was performed in 103. Fifty contact allergic reactions were noted in 26 players. When comparing the reactions present on day 3 with the photos from day 7, seven (14%) more positive reactions were registered. The seven additional reactions were noted to seven different sensitizers: hexavalent chromium, oxidized linalool, thiomersal, mercapto mix, mercaptobenzothiazole, PFR-2 (a resol resin based on phenol and formaldehyde) and methylenedianiline. In summary, 14% more contact allergic reactions were diagnosed when using photos of the tested backs to replace the traditional dermatologist reading.
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