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Sökning: WFRF:(Iselius Lennart) > (2010-2014)

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1.
  • Sluys, Kerstin, 1956- (författare)
  • Adult and pediatric trauma : outcomes and health-related quality of life
  • 2012
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • Background: Trauma is the number one killer of children and young adults and the  most common cause for hospital admissions for these age-groups in Sweden. Trauma is  also one of the most common causes for hospital care and early death for older people.  In the last decades trauma care has advanced and improved short-term survival of  injured but knowledge of the long-term outcome is limited.The overall aim of this thesis is to investigate long-term outcome and health-related  quality of life after injuries in different age groups and to identify factors associated  with outcome.Methods: The thesis is based on four studies. In the first study patients with major  trauma were contacted 5 years after injury and HRQL was measures using the SF-36  questionnaire and compared to an age and sex-matched reference group. In the second  study data was collected on children with injuries to describe demographic and injury  characteristics and outcome. The sample in the second study was the source for the  third and fourth study. The third study measured HRQL using the PedsQL 4.0 in a  cohort of children 6 years after injury and determined the relationship within subgroups  in the cohort. The fourth study measured child HRQL in a sample of children after  injury and their parent´s and determined the relationship within scoring results and the impact of parents reported mental health status.Results: The adult major trauma patients (n=205) reported significantly lower HRQL  scores in all eight domains compared to the reference group. A large number of patients  suffered from physical (68%) and psychological disabilities (41%) and nearly half reported the need for better follow-up after discharge from hospital. The severity of the injury did not anticipate a lower health-related quality of life. In the pediatric group  (n=432) the median injury severity score was 4 (IQR 1-9), 50% sustained head injuries  and the most severe head injuries were seen in the youngest age group. Mortality rate  was low (1%), 19% stayed in a PICU and the median length of hospital stay was two  days. In the follow-up study (n=204) the youngest children had the lowest PedsQL  scores. Children who suffered from extremity injuries had lower scores in the school  functioning compared to children with head injuries. The levels of agreement between  child self-report and parent proxy report of PedsQL 4.0 scales were excellent  (ICC≥0.80) for all scales with the exception of children´s self-reported emotional  functioning. Multiple regression analyses showed that poor parental mental health  status contributed to worse child self-report and parent proxy report of children´s  HRQL.Conclusion: Adult major trauma patients have significant disabilities 5 years after  injury. Improved follow-up by trauma specialist teams are needed. Children´s HRQL 6  years after trauma seems to in parity or better than healthy peers. Parent´s mental health  status can possibly impact on children´s HRQL long after an injury. Further studies are  recommended to evaluate the PedsQL 4.0versions for self-report in pediatric trauma  population.
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2.
  • Sluys, Kerstin, 1956-, et al. (författare)
  • Outcomes in Pediatric Trauma Care in the Stockholm Region
  • 2010
  • Ingår i: European Journal of Trauma and Emergency Surgery. - Berlin : Springer Berlin/Heidelberg. - 1863-9933 .- 1863-9941. ; 36:4, s. 308-317
  • Tidskriftsartikel (refereegranskat)abstract
    • Background:Although trauma is a leading cause of pediatric mortality and morbidity in Sweden, few studies have examined the outcome of pediatric trauma.Objective:Here, we describe the age and gender distribution, injury mechanisms, injury severity, and outcome of pediatric trauma in the Stockholm region.Methods:This retrospective study comprises all trauma patients (age ≤ 15 years) admitted to a regional pediatric trauma center and all pediatric deaths due to trauma in Stockholm in 2002. Data from the trauma registry database were verified by comparison with medical records and autopsy reports. Outcome was measured by mortality and length of stay in a pediatric intensive care unit (PICU) and acute care hospital.Results:In all, 432 injured children were included. The median age was 10 years and 59% were males. The median injury severity score was 4 (interquartile range [IQR] 1–9) and 50% sustained head injuries. Mortality was low (1%) and the median length of hospital stay was 2 days (IQR 1–3); 19% stayed in a PICU and, of those, 89% stayed for one day. Comparison with medical records showed that much information in the trauma registry database was either incorrect or missing.Conclusions:Many injuries were minor and half of the children were discharged home from the emergency department. Head injuries were the most common injury in all age groups. The most severe head injuries were seen in the youngest group and were caused by falls. Trauma team activation criteria should be improved to avoid overutilization. The quality and completeness of data in the trauma registry must be enhanced.
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