| 1. |
- Chimuka, Luke, et al.
(författare)
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Application of membrane-based extraction techniques to food and agricultural samples
- 2006
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Ingår i: Modern extraction techniques; food and agricultural samples (ACS symposium series). - 0097-6156. - 9780841239401 - 0841239401 ; 926, s. 149-162
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The use of membrane-based extractions are increasingly seen as offering an alternative to conventional sample preparation procedures in analysis of chemical species in both food and agricultural samples. In this article, emphasis is placed on the attractiveness of membrane based extraction techniques to a variety of food and agricultural samples such as circulating nutrient solutions, fruit juices, fruits, beverages, vegetables, food oils and others. Examples of membrane based applications demonstrating how selective these techniques are even for food and agricultural samples are given.
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| 2. |
- Domeij, Maria, et al.
(författare)
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Utställningen Odens öga -att binda samman, transformera och visualisera
- 2006
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Ingår i: Odens öga - mellan människor och makter i det förkristna Norden.. - 1651-6796. - 9789197455053 - 9197455059 ; , s. 20-31
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Bokkapitel (populärvet., debatt m.m.)abstract
- Artikeln handlar om arbetet med utställningen Odens öga - mellan människor och makter i det förksristna Norden.
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| 3. |
- Jönsson, Charlotta, et al.
(författare)
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Pole walking for patients with breast cancer-related arm lymphedema.
- 2009
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Ingår i: Physiotherapy Theory and Practice. - : Informa UK Limited. - 0959-3985 .- 1532-5040. ; 25:3, s. 165-173
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Tidskriftsartikel (refereegranskat)abstract
- Arm lymphedema is a well-known side effect of breast cancer treatment. Studies of the effect of physical exercise on arm lymphedema are very rare. The purpose of this study was to investigate the influence of pole walking on breast cancer-related arm lymphedema when using a compression sleeve. Twenty-six women with unilateral arm lymphedema took part in a clinical study of pole walking on one occasion, 4 kilometers for 1 hour. Measurements were made before, immediately after, and 24 hours later. Results revealed no changes in total arm volume of the swollen arm, measured with water displacement method, or in subjective assessments of heaviness and tightness in the affected arm using visual analogue scale. Immediately after pole walking, a temporary increase in total arm volume of the healthy arm (P=0.037) was found. Twenty-four hours later, no differences were found compared to the measurements before walking. The median for perceived exertion immediately after pole walking, measured with Borg scale, was 11 ("fairly light"). The results suggest that a controlled, short-duration pole-walking program can be performed by patients with arm lymphedema, using a compression sleeve, without deterioration of the arm lymphedema.
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| 4. |
- Levay, Charlotta, et al.
(författare)
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Karismatiskt ledarskap
- 2009
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Ingår i: Ledarskapsboken. - 9789147088751 ; , s. 316-331
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 5. |
- Magnusson, Marie V, et al.
(författare)
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Pentoxifylline and vitamin E treatment for prevention of radiation-induced side-effects in women with breast cancer : a phase two, double-blind, placebo-controlled randomised clinical trial (Ptx-5)
- 2009
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Ingår i: European Journal of Cancer. - Oxford : Elsevier. - 0959-8049 .- 1879-0852. ; 69:24, s. 740-740
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Tidskriftsartikel (refereegranskat)abstract
- Background: A previous study has shown that pentoxifylline in combination with vitamin E can reverse radiation-induced fibrosis. The aim of the present study is to investigate if the same drugs could prevent radiation-induced side-effects in women with breast cancer.Patients and methods: A randomised, placebo-controlled, double-blind, parallel group trial was performed. Women with breast cancer were treated for 12 months with 400 mg pentoxifylline t.i.d. or placebo, in combination with 100 mg vitamin E t.i.d,, starting 1-3 months after the completion of radiotherapy. The primary end-point was passive abduction of the shoulder, and the secondary end-point was difference in arm volumes. The trial is registered on the ISRCTN.org website, number ISRCTN39143623.Results: 83 patients were included in the study; 42 in the pentoxifylline + vitamin E group and 41 in the placebo + vitamin E group. Both treatments were generally well tolerated. Seven patients were withdrawn from the treatment due to disease progression; four in the pentoxifylline group and three in the placebo group. At inclusion, patients had impaired passive abduction of the shoulder. During treatment, both the groups improved significantly. Median improvement from baseline was 3.7 degrees (p = 0.0035) on pentoxifylline and was 9.4 degrees (p = 0.0041) in the placebo group, but no difference between the groups was detected (p = 0.20). Arm volumes increased over time in the placebo group (1.04%), but not on pentoxifylline (0.50%), and differed significantly between the groups (p = 0.0172).Conclusions: The combination of pentoxifylline and vitamin E was safe and may be used for the prevention of some radiation-induced side-effects. (C) 2009 Elsevier Ltd. All rights reserved.
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| 6. |
- Nilsson, Ulrika, et al.
(författare)
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Tamoxifen decreases extracellular TGF-beta 1 secreted from breast cancer cells - A post-translational regulation involving matrix metalloproteinase activity
- 2009
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Ingår i: Experimental Cell Research. - : Elsevier BV. - 0014-4827 .- 1090-2422. ; 315:1, s. 1-9
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Tidskriftsartikel (refereegranskat)abstract
- Transforming growth factor-beta 1 (TGF-beta 1) promotes cancer progression by regulating tumor cell growth and angiogenesis and high levels of TGF-beta 1 have been associated with metastatic disease and poor prognosis in breast cancer patients. We have previously reported anti-angiogenic effects of the anti-estrogen tamoxifen in breast cancer, by increased matrix metalloproteinase-9 (MMP-9) activity and generation of endostatin. Here, we show that exposure of tamoxifen to ER-positive breast cancer cells for 7 days, decreased extracellular TGF-beta 1. Intracellular TGF-beta 1 levels were unaffected by tamoxifen treatment, indicating a post-translational regulation of TGF-beta 1. Inhibition of MMP activity restored TGF-beta 1 levels, suggesting an involvement of MMP activities in the down-regulation of TGF-beta 1 by tamoxifen. Moreover, using an in vivo model of solid MCF-7 tumors in nude mice, we analyzed tumor levels of TGF-beta 1 after in vivo treatment with estradiol and tamoxifen. Exposure of tumor-bearing mice to tamoxifen significantly decreased tumor TGF-beta 1 protein levels, tumor growth and angiogenesis. In conclusion, our findings suggest a novel mechanism of action of tamoxifen in breast cancer via sex steroid dependent modulation of the proteolytic tumor microenvironment resulting in reduced extracellular TGF-beta 1 levels.
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| 7. |
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