| 1. |
- Jönsson, Anders, 1959, et al.
(författare)
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Effects of amide local anaesthetics on eicosanoid formation in burned skin.
- 1999
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Ingår i: Acta anaesthesiologica Scandinavica. - 0001-5172. ; 43:6, s. 618-22
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Tidskriftsartikel (refereegranskat)abstract
- Previous studies have demonstrated potent inhibition of burn oedema and progressive ischaemia by local anaesthetics. Since eicosanoids have been suggested to play an important role in the pathophysiology of burns, we compared in the present ex vivo study the effects of topical lidocaine/prilocaine cream (EMLA, ASTRA, Sweden) and intravenous lidocaine with that of saline on eicosanoid formation by normal and burned rat skin.
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| 2. |
- Jönsson, Robert, et al.
(författare)
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The Swedish Case Study, Different Fire Safety Design Methods Applied on a High Rise Building
- 1998
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The present report concerns a performance-based fire safety analysis and design of a high-rise building. The resulting fire safety recommendations are compared with those specified by acceptable solutions in terms of the earlier prescriptive building code. The respective risk to life resulting from the analyses is compared and discussed. The benefit and need of using a risk based verification method as a complement to a deterministic fire safety engineering method is demonstrated. The cost-effectiveness of different solutions is also demonstrated.
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| 3. |
- Marberg, Per-Anders, et al.
(författare)
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Practical Design and Performance Based Regulations
- 1998
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Ingår i: Fire Science and Technology. - 0285-9521. ; 18:1, s. 33-42
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Tidskriftsartikel (refereegranskat)abstract
- The paper presents a sample design of a multi-storey building with respect to the fire safety. Three design strategies are examined, a standard solution according to the requirements, a fire safety engineering design without a sprinkler system and finally a fire safety engineering design with a sprinkler system. The objective was to demonstrate different design strategies and still comply with the performance based Swedish building regulation. Mostly, only the safety to people has been considered in the design for the three cases. The use of fire safety engineering methods for the design shows that an optimised solution can be achieved with respect to both fire safety and economics.
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| 4. |
- Marberg, Per-Anders, et al.
(författare)
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The Swedish Case Study, Fire Safety Design for a Multitenant Business Occupancy
- 1996
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The report presents a sample design of a multi-storey building with respect to the fire safety. Three design strategies are examined, a standard solution according to the requirements, a fire safety engineering design without a sprinkler system and finally a fire safety engineering solution with a sprinkler system. Both occupant safety and structural safety have been considered in the design for the three cases. The use of fire safety engineering methods for the design shows that an optimised solution can be achieved with respect to both fire safety and economics. An executive summary is also attached to the report, which describes the major findings.
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| 5. |
- Mattsson, Ulf, 1955, et al.
(författare)
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Digital image analysis of erythema development after experimental thermal injury to human skin: effect of postburn topical local anesthetics (EMLA).
- 1999
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Ingår i: Anesthesia and analgesia. - 0003-2999. ; 88:5, s. 1131-6
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Tidskriftsartikel (refereegranskat)abstract
- Local anesthetics inhibit edema and improve circulation in experimental burns. We evaluated the effect of topical local anesthetics on human skin burns in volunteers using computerized color analysis that allowed repeated noninvasive quantitative measurements. A standardized partial-thickness burn (1 cm2) was induced in one forearm of 10 healthy volunteers and in the opposite forearm a week later. The burned areas were treated with lidocaine/prilocaine cream (EMLA; Astra, Sweden) or a placebo cream for 1 h. The experimental skin area was photographed before and 1, 2, 4, and 12 h postburn. Digitized images were evaluated using normalized red-green-blue and Hue-Saturation-Intensity. Differences in erythema between skin treated with EMLA and placebo were not significant during the first 4 h postburn. However, 12 h postburn, a pronounced decrease in the degree of erythema was observed in EMLA-treated skin compared with placebo-treated skin. We conclude that topical local anesthetics administered for 1 h postburn significantly reduces the duration of erythema after a mild thermal injury, which suggests a potential use in clinical practice in the treatment of minor skin burns.
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