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- Bauer, C, et al.
(författare)
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Photooxidation of an azo dye induced by visible light incident on the surface of TiO2
- 2001
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Ingår i: JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY. - : ELSEVIER SCIENCE SA. - 1010-6030. ; 140:1, s. 87-92
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Tidskriftsartikel (refereegranskat)abstract
- Oxidation of Acid Orange 7 (AO7) induced by visible light on TiO2 surfaces has been probed by FT-IR spectroscopy for identification and kinetic studies of degradation products. The tautomerism has been considered for this type of azo dye. The hydrazone fo
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- Belz, Gabrielle T, et al.
(författare)
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The CD8alpha+ dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens.
- 2002
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Ingår i: Journal of Experimental Medicine. - : The Rockefeller University Press. - 0022-1007 .- 1540-9538. ; 196:8, s. 1099-1104
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Tidskriftsartikel (refereegranskat)abstract
- We previously described a mechanism for the maintenance of peripheral self-tolerance. This involves the cross-presentation of tissue-associated antigens by a bone marrow-derived cell type that stimulates the proliferation and ultimate deletion of self-reactive CD8 T cells. This process has been referred to as cross-tolerance. Here, we characterize the elusive cell type responsible for inducing cross-tolerance as a CD8alpha(+) dendritic cell (DC). To achieve this aim, transgenic mice were generated expressing yellow fluorescent protein (YFP) linked to CTL epitopes for ovalbumin and glycoprotein B (gB) of herpes simplex virus under the rat insulin promoter (RIP). Although tracking of YFP was inconclusive, the use of a highly sensitive gB-specific hybridoma that produced beta-galactosidase on encounter with antigen, enabled detection of antigen presentation by cells isolated from the pancreatic lymph node. This showed that a CD11c(+)CD8alpha(+) cell was responsible for cross-tolerance, the same DC subset as previously implicated in cross-priming. These data indicate that CD8alpha(+) DCs play a critical role in both tolerance and immunity to cell-associated antigens, providing a potential mechanism by which cytotoxic T lymphocyte can be immunized to viral antigens while maintaining tolerance to self.
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5. |
- Tong, Longyu, et al.
(författare)
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Photo-dissociation of hydrogen passivated dopants in gallium arsenide
- 2002
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Ingår i: Nuclear Instruments and Methods in Physics Research Section B. - 0168-583X .- 1872-9584. ; 186:1-4, s. 234-239
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Tidskriftsartikel (refereegranskat)abstract
- A theoretical and experimental study of the photo-dissociation mechanisms of hydrogen passivated n- and p-type dopants in gallium arsenide is presented. The photo-induced dissociation of the Si Ga-H complex has been observed for relatively low photon energies (3.48 eV), whereas the photo-dissociation of C As-H is not observed for photon energies up to 5.58 eV. This fundamental difference in the photo-dissociation behavior between the two dopants is explained in terms of the localized excitation energies about the Si-H and C-H bonds.
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