SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Jafferali Mohammed Hakim)
 

Sökning: WFRF:(Jafferali Mohammed Hakim) > (2023) > Long-term SARS-CoV-...

Long-term SARS-CoV-2 surveillance in the wastewater of Stockholm : What lessons can be learned from the Swedish perspective?

Perez-Zabaleta, Mariel, 1987- (författare)
KTH,Resursåtervinning,Industriell bioteknologi,Albanova VinnExcellence Center for Protein Technology, ProNova
Archer, Amena (författare)
Karolinska Institutet,KTH,Science for Life Laboratory, SciLifeLab,Cellulär och klinisk proteomik
Khatami, Kasra (författare)
KTH,Kemiteknik,Albanova VinnExcellence Center for Protein Technology, ProNova,Industriell bioteknologi
visa fler...
Jafferali, Mohammed Hakim (författare)
KTH,Proteinvetenskap,Science for Life Laboratory, SciLifeLab
Nandy, Prachi (författare)
KTH,Kemiteknik
Atasoy, Merve, PhD, 1990- (författare)
KTH,Resursåtervinning
Birgersson, Madeleine (författare)
Karolinska Institutet,KTH,Science for Life Laboratory, SciLifeLab,Proteinvetenskap
Williams, Cecilia, Professor, 1969- (författare)
KTH,Science for Life Laboratory, SciLifeLab,Cellulär och klinisk proteomik
Cetecioglu, Zeynep, PhD, 1981- (författare)
KTH,Industriell bioteknologi,Resursåtervinning,Albanova VinnExcellence Center for Protein Technology, ProNova
visa färre...
 (creator_code:org_t)
Elsevier BV, 2023
2023
Engelska.
Ingår i: Science of the Total Environment. - : Elsevier BV. - 0048-9697 .- 1879-1026. ; 858
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Wastewater-based epidemiology (WBE) can be used to track the spread of SARS-CoV-2 in a population. This study pre-sents the learning outcomes from over two-year long monitoring of SARS-CoV-2 in Stockholm, Sweden. The three main wastewater treatment plants in Stockholm, with a total of six inlets, were monitored from April 2020 until June 2022 (in total 600 samples). This spans five major SARS-CoV-2 waves, where WBE data provided early warning signals for each wave. Further, the measured SARS-CoV-2 content in the wastewater correlated significantly with the level of positive COVID-19 tests (r = 0.86; p << 0.0001) measured by widespread testing of the population. Moreover, as a proof-of-concept, six SARS-CoV-2 variants of concern were monitored using hpPCR assay, demonstrating that var-iants can be traced through wastewater monitoring.During this long-term surveillance, two sampling protocols, two RNA concentration/extraction methods, two calcula-tion approaches, and normalization to the RNA virus Pepper mild mottle virus (PMMoV) were evaluated. In addition, a study of storage conditions was performed, demonstrating that the decay of viral RNA was significantly reduced upon the addition of glycerol to the wastewater before storage at -80 degrees C. Our results provide valuable information that can facilitate the incorporation of WBE as a prediction tool for possible future outbreaks of SARS-CoV-2 and preparations for future pandemics.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Infectious Medicine (hsv//eng)

Nyckelord

Severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2)
COVID-19
Wastewater-based epidemiology (WBE)
Storage conditions
Sewage surveillance
hpPCR

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy