| 1. |
- Jansson, Kjell, 1958-, et al.
(författare)
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Normal values and differences between intraperitoneal and subcutaneous microdialysis in patients after non‐complicated gastrointestinal surgery
- 2005
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Ingår i: Scandinavian Journal of Clinical and Laboratory Investigation. - : Informa UK Limited. - 0036-5513 .- 1502-7686. ; 65:4, s. 273-282
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Tidskriftsartikel (refereegranskat)abstract
- Objective. Visceral ischemia is an early event in the development of shock and organ failure. Microdialysis has been presented as a promising method for detection of visceral hypoxia and ischemia. The aim of this study was to investigate differences in the metabolic response measured by microdialysis between intraperitoneal and subcutaneous locations and to estimate normal values of lactate/pyruvate ratio, glucose and glycerol. Material and methods. Intraperitoneal and subcutaneous metabolic responses were compared regarding lacate/pyruvate ratio, glucose and glycerol, during 45 postoperative hours in 33 patients undergoing various non‐complicated elective major gastrointestinal surgery. Results. Intraperitoneal lactate/pyruvate ratio started around 15 and decreased over time, while subcutaneous levels were stable around 9. Glucose levels were higher intraperitoneally and increased rapidly during the first 9 h to 8.6 mM, while the subcutaneous levels increased during 21 h to 7.5 mM. Intraperitoneal glycerol levels were stable around 100 µM, while subcutaneous values started around 230 µM and then increased. Conclusions. In a non‐complicated postoperative course the lactate/pyruvate ratio and glucose levels are higher intraperitoneally, suggesting a higher postoperative intraperitoneal metabolism. Glycerol levels are higher and increase subcutaneously, suggesting increased postoperative energy demand, particularly in the visceral organs, as being responsible for the lipolysis seen in the subcutaneous tissue.
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| 2. |
- Christensen, Kirsten E., et al.
(författare)
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An open-framework silicogermanate with 26-ring channels built from seven-coordinated (Ge,Si)10(O, OH)28 clusters
- 2008
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Ingår i: Journal of the American Chemical Society. - : American Chemical Society (ACS). - 0002-7863 .- 1520-5126. ; 130:12, s. 3758-3759
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Tidskriftsartikel (refereegranskat)abstract
- We report a new open-framework silicogermanate SU-61 containing 26-ring channels with a low framework density. It can be seen as a crystalline analogue to the mesoporous silica MCM-41. The structure is built from the assembly of (Ge,Si)10(O,OH)28 clusters. It is the first time that silicon has been successfully introduced in the Ge10 cluster in significant amounts (21% of the tetrahedral sites). Five- and six-coordinated Ge10 clusters have previously been observed in other germanate compounds leading to either dense or open structures. In SU-61, the seven-coordinated clusters fall onto yet another underlying net, the osf net. SU-61, along with other Ge10 based frameworks, shows the versatility of the germanate system to adopt defined topologies playing on the connectivity of the clusters following the principles of net decoration and scale chemistry.
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| 3. |
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| 4. |
- Cinthio, Magnus, et al.
(författare)
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Longitudinal movements and resulting shear strain of the arterial wall
- 2006
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Ingår i: American Journal of Physiology: Heart and Circulatory Physiology. - : American Physiological Society. - 1522-1539 .- 0363-6135. ; 291:1, s. 394-402
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Tidskriftsartikel (refereegranskat)abstract
- There has been little interest in the longitudinal movement of the arterial wall. It has been assumed that this movement is negligible compared with the diameter change. Using a new high-resolution noninvasive ultrasonic method, we measured longitudinal movements and diameter change of the common carotid artery of 10 healthy humans. During the cardiac cycle, a distinct bidirectional longitudinal movement of the intima-media complex could be observed in all the subjects. An antegrade longitudinal movement, i.e., in the direction of blood flow, in early systole [ 0.39 mm ( SD 0.26)] was followed by a retrograde longitudinal movement, i.e., in the direction opposite blood flow [ -0.52 mm ( SD 0.27)], later in systole and a second antegrade longitudinal movement [ 0.41 mm ( SD 0.33)] in diastole. The corresponding diameter change was 0.65 mm ( SD 0.19). The adventitial region showed the same basic pattern of longitudinal movement; however, the magnitude of the movements was smaller than that of the intimamedia complex, thereby introducing shear strain and, thus, shear stress within the wall [ maximum shear strain between the intima-media complex and the adventitial region was 0.36 rad ( SD 0.26). These phenomena have not previously been described. Measurements were also performed on the abdominal aorta ( n = 3) and brachial ( n = 3) and popliteal ( n = 3) arteries. Our new information seems to be of fundamental importance for further study and evaluation of vascular biology and hemodynamics and, thus, for study of atherosclerosis and vascular diseases.
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| 5. |
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| 6. |
- Cinthio, Magnus, et al.
(författare)
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New Approaches in Arterial Characterisation
- 2008
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Ingår i: Proceedings of 11th International Symposium on Advanced Biomedical Ultrasound (Invited). ; , s. 3-8
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- —The aim of this paper is to briefly present the historyand the status of the arterial characterization of today as wellas summarize our work on two new approaches in arterialcharacterization – measurements of the longitudinal movementand the minute roughness of the arterial wall.
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| 7. |
- Cinthio, Magnus, et al.
(författare)
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New improved and modified method for measurements of arterial wall movements in longitudinal and radial directions
- 2005
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Ingår i: Medical physics : proceedings of the jointly held congresses ICMP 2005, 14th International Conference of the Medical Physics of the International Organization for Medical Physics (IOMP), the European Federation of Organisations in Medical Physics (EFOMP) and the German Society of Medical Physics (DGMP) [and] BMT 2005, 39th annual congress of the German Society for Biomedical Engineering (DGBMT) ; 14th - 17th September 2005, Nuremberg, Germany. ; 50, s. 869-870
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 8. |
- Cinthio, Magnus, et al.
(författare)
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New improved method for 2D arterial wall movement measurements
- 2005
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Ingår i: Proceedings of the International Federation for Medical & Biomedical Engineering. 13th Nordic Baltic Conference on Biomedical Engineering and Medical Physics. - 9173059102 ; , s. 117-118
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Konferensbidrag (refereegranskat)abstract
- We have recently reported that the inner layers of the arteries, the intima-media complex, of common carotid artery, move as much in the longitudinal direction as in the radial direction, during the cardiac cycle. In order to study this phenomenon we have developed a high-resolution ultrasonic method that can simultaneously record both the longitudinal and the radial movements of the arterial wall non-invasively in vivo. However, in young individuals with large movements and with thin intima-media complex it happens sometimes that the echoes from the adventitia region interfere. To be able to minimise the size of the region-of-interest in the radial direction, we suggest that the radial movement of the arterial vessel is first measured and that the radial movement is used as a priori information when the longitudinal movement is measured. The mean difference between the two methods is 8 and 2 standard deviation is 24 μm
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| 9. |
- Cinthio, Magnus, et al.
(författare)
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New non-invasive method for intima-media thickness and intima-media compression measurements
- 2005
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Ingår i: Proceedings - IEEE Ultrasonics Symposium. - 1051-0117. - 0780393821 ; 1, s. 389-392
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Konferensbidrag (refereegranskat)abstract
- Intim a-media thickness (IMT) is considered as a valuable marker of early atherosclerosis. We suggest a new algorithm for simultaneous measurements of absolute diameter at diastole, distension (diameter change), IMT at diastole and the intima-media compression (IMC) with a new fast, robust, high-resolution, and automatic algorithm utilizing the ultrasonic gray-scale information. The new algorithm is evaluated in a limited in vivo study on the common carotid artery of 5 healthy volunteers. The standard deviation within an investigation was (8 ± 4 μm; range 4-14 μm) during IMC measurements, (8 ± 5 μm; range 4-16 μm) during the measurements of the IMT at diastole, (30 ±36 μm; range 6-92 μm) during the distension measurements and (48 ±49 μm; range 15-134 μm) during the measurements of the lumen diameter at diastole. The evaluation shows that the algorithm is fast and that the reproducibility and resolution are more than sufficient for in vivo studies. © 2005 IEEE.
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| 10. |
- Cinthio, Magnus, et al.
(författare)
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Non-invasive measurements of longitudinal strain of the arterial wall
- 2007
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Ingår i: Ultrasonics Symposium, 2007. IEEE, vols 1-6. - 1051-0117. - 9781424413843 ; , s. 570-572
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Konferensbidrag (refereegranskat)abstract
- We have recently shown that there is a previous unknown longitudinal movement present in the arterial wall. The aim is now to investigate whether the longitudinal movement is associated with longitudinal strain of the arterial wall. The objective of this paper was to describe a new non-invasive ultrasonic technique that measures the longitudinal strain of arteries in human in-vivo. Results indicate that a longitudinal strain is present in the common carotid artery.
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