| 1. |
- Abrahamsen, Rune, et al.
(författare)
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Dynamic Response of Tall Timber Buildings Under Service Load : The DynaTTB Research Program
- 2020
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Ingår i: EURODYN 2020, XI international conferece on structural dynamics. - : National Technical University of Athens. - 9786188507210 ; , s. 4900-4910
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Konferensbidrag (refereegranskat)abstract
- Wind-induced dynamic excitation is becoming a governing design action determin-ing size and shape of modern Tall Timber Buildings (TTBs). The wind actions generate dynamic loading, causing discomfort or annoyance for occupants due to the perceived horizontal sway – i.e. vibration serviceability failure. Although some TTBs have been instrumented and meas-ured to estimate their key dynamic properties (natural frequencies and damping), no systematic evaluation of dynamic performance pertinent to wind loading has been performed for the new and evolving construction technology used in TTBs. The DynaTTB project, funded by the Forest Value research program, mixes on site measurements on existing buildings excited by heavy shakers, for identification of the structural system, with laboratory identification of building elements mechanical features coupled with numerical modelling of timber structures. The goal is to identify and quantify the causes of vibration energy dissipation in modern TTBs and pro-vide key elements to FE modelers.The first building, from a list of 8, was modelled and tested at full scale in December 2019. Some results are presented in this paper. Four other buildings will be modelled and tested in spring 2020.
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| 2. |
- Abrahamsen, Rune, et al.
(författare)
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Dynamic response of tall timber buildings under service load : results from the dynattb research program
- 2023
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Ingår i: World Conference on Timber Engineering 2023 (WCTE 2023). - : Curran Associates, Inc.. - 9781713873297 ; , s. 2907-2914
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Konferensbidrag (refereegranskat)abstract
- Wind-induced dynamic excitation is a governing design action determining size and shape of modern Tall Timber Buildings (TTBs). The wind actions generate dynamic loading, causing discomfort or annoyance for occupants due to the perceived horizontal sway, i.e. vibration serviceability problem. Although some TTBs have been instrumented and measured to estimate their key dynamic properties (eigenfrequencies, mode shapes and damping), no systematic evaluation of dynamic performance pertinent to wind loading had been performed for the new and evolving construction technologies used in TTBs. The DynaTTB project, funded by the ForestValue research program, mixed on site measurements on existing buildings excited by mass inertia shakers (forced vibration) and/or the wind loads (ambient vibration), for identification of the structural system, with laboratory identification of building elements mechanical features, coupled with numerical modelling of timber structures. The goal is to identify and quantify the causes of vibration energy dissipation in modern TTBs and provide key elements to finite element models. This paper presents an overview of the results of the project and the proposed Guidelines for design of TTBs in relation to their dynamic properties.
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| 3. |
- Björnerås, Caroline, et al.
(författare)
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Inland blue holes of The Bahamas - chemistry and biology in a unique aquatic environment
- 2020
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Ingår i: Fundamental and Applied Limnology. - : Schweizerbart science publishers. - 1863-9135. ; 194:2, s. 95-106
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Tidskriftsartikel (refereegranskat)abstract
- While lake systems in temperate regions have been extensively studied, tropical and subtropical systems have received less attention. Here, we describe the water chemistry and biota of ten inland blue holes on Andros Island, The Bahamas, representative of the morphological, abiotic, and biotic variation among Androsian inland blue holes. The majority of the studied blue holes were vertically stratified with oxic freshwater overlying anoxic saline groundwater of marine origin. Water chemistry (e.g. total phosphorus and nitrogen) in shallow waters was similar among blue holes, while turbidity and water color varied. Presence of hydrogen sulfide and reduced iron in and below the halocline indicate reducing conditions in all stratified blue holes. The biota above the halocline was also similar among blue holes with a few taxa dominating the phytoplankton community, and the zooplankton community consisting of copepods and rotifers. The Bahamas mosquitofish (Gambusia hubbsi) was present in all investigated blue holes, often accompanied by other small planktivorous fish, while the piscivorous bigmouth sleeper (Gobiomorus donnitor) was only present in some of the blue holes. Our field study reinforces that inland blue holes are highly interesting for biogeochemical research, and provide naturally replicated systems for evolutionary studies.
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| 4. |
- Pärssinen, Varpu, et al.
(författare)
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Variation in predation regime drives sex-specific differences in mosquitofish foraging behaviour
- 2021
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Ingår i: Oikos. - : Wiley-Blackwell. - 0030-1299 .- 1600-0706. ; 130:5, s. 790-797
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Tidskriftsartikel (refereegranskat)abstract
- Predation is a well-studied driver of ecological selection on prey traits, which frequently drives divergence in anti-predator performance across environments that vary in predation risk. However, predation also alters prey mortality regimes, where low predation risk often results in higher prey densities and consequently higher intensities of intraspecific resource competition. In addition, predation risk alters the foraging context, as acquiring food can be risky in the presence of predators. Thus, different predation regimes can drive divergent selection on traits associated with resource competition, such as foraging behaviours. Moreover, because sexes often differ in susceptibility to predation and limitations to their reproductive output, the intensity of the tradeoff between predator avoidance and resource competition may depend on sex. We used a laboratory experiment to assess key aspects of foraging performance in a predator-free context in Bahamas mosquitofish Gambusia hubbsi wild-caught from multiple populations that experience either high or low levels of predation risk. When competing for limited food resources at a common density, females from low-predation regimes showed higher foraging and food consumption rates than females from high-predation regimes. Males showed fewer differences between predation regimes, and an opposite pattern from females. We suggest these sex-specific effects result from females facing a greater tradeoff between predation risk and resource competition, combined with males from high-predation environments elevating foraging behaviours in the absence of nearby predators and females. Females of this species are larger than males, bear live young and show higher foraging rates in the wild than males. On the other hand, males spend more time pursuing females in the wild, and may exhibit greater flexibility in foraging behaviours based on the immediate context. Our results show that varying levels of predation risk can lead to differences in behaviours associated with resource competition, but these effects can strongly differ between sexes.
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| 5. |
- Agarwal, Girish Kumar, et al.
(författare)
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Edge AI Driven Technology Advancements Paving Way towards New Capabilities
- 2020
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Ingår i: International Journal of Innovation and Technology Management (IJITM). - : World Scientific. - 0219-8770.
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Tidskriftsartikel (refereegranskat)abstract
- As industries hold the opportunity to embrace artificial intelligence (AI) driven innovation, their success to a significant extent will depend on the value the new technology generates for different business stakeholder groups. This is in turn dependent upon how management can embrace these techniques and change as companies will frequently need to transform both internal processes and offerings to customers in order to reap the benefits of AI. AI is a growing research area currently concentrated around technology and modeling of techniques and yet only few examples and limited research are available, on how AI technology enables new capabilities that can impact the value delivered as well as radically transform it. We thus need to understand what new capabilities these technologies bring about and how they are used. Based on three concrete empirical quasi-experiments, interviews conducted with start-ups and a Swedish industrial manufacturing firm dealing with outdoor power products (like grass-cutters, chain-saws, concrete-saws, etc.) for professional and consumer use and using an analytical framework derived from the Resource Based View, this paper explores capabilities enabled through Edge AI and the competitive advantage these may offer. Specific capabilities (self-calibration, enhanced-sensing, selective-capture and reputation) are identified and implications for theory are discussed, pointing out the importance to consider this type of technology not only as a resource, but rather as a dynamic capability in itself.
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| 6. |
- Agarwal, Girish Kumar, et al.
(författare)
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Value Changes during Service Delivery
- 2021
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Ingår i: 2021 IEEE International Conference on Engineering, Technology and Innovation (ICE/ITMC). - : Institute of Electrical and Electronics Engineers (IEEE).
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Konferensbidrag (refereegranskat)abstract
- Most industries are shifting from product-orientedbusiness models towards services to step up the value chain andengage in long-term relationships with their customersthroughout the service lifecycle. Digital technologies arecontributing to servitization in many ways by creating andenabling capabilities like connectivity, IoT, data generation andassessment, etc., for new value generation, distribution, andcapture. Because value is subjective, dynamic, and changes duringthe service lifecycle, service providers need to examine closely thevalue perceptions of customers to constantly provide better valueand remain relevant with the competition. Through a consumersurvey and a longitudinal study of thirteen customers, this paperuses qualitative and quantitative assessment to identify the valuedimensions that play a major role for customers being onboardedon a digital enabled service, and also highlights how customervalue dimensions change over the course of the service lifecycle.One important finding is that change in customer value perceptiondoes not follow a pattern and is highly individual and personal.This opens a discussion regarding the need for hyperpersonalizationin successful servitization, and the role of digitaltechnologies towards the same.
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| 7. |
- Aranda-Guillén, Maribel, et al.
(författare)
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A polygenic risk score to help discriminate primary adrenal insufficiency of different etiologies.
- 2023
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Ingår i: Journal of internal medicine. - : John Wiley & Sons. - 0954-6820 .- 1365-2796. ; 294:1, s. 96-109
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Tidskriftsartikel (refereegranskat)abstract
- Autoimmune Addison's disease (AAD) is the most common cause of primary adrenal insufficiency (PAI). Despite its exceptionally high heritability, tools to estimate disease susceptibility in individual patients are lacking. We hypothesized that polygenic risk score (PRS) for AAD could help investigate PAI pathogenesis in pediatric patients.We here constructed and evaluated a PRS for AAD in 1223 seropositive cases and 4097 controls. To test its clinical utility, we reevaluated 18 pediatric patients, whose whole genome we also sequenced. We next explored the individual PRS in more than 120 seronegative patients with idiopathic PAI.The genetic susceptibility to AAD-quantified using PRS-was on average 1.5 standard deviations (SD) higher in patients compared with healthy controls (p<2e-16), and 1.2 SD higher in the young patients compared with the old (p=3e-4). Using the novel PRS, we searched for pediatric patients with strikingly low AAD susceptibility and identified cases of monogenic PAI, previously misdiagnosed as AAD. By stratifying seronegative adult patients by autoimmune comorbidities and disease duration we could delineate subgroups of PRS suggesting various disease etiologies.The PRS performed well for case-control differentiation and susceptibility estimation in individual patients. Remarkably, a PRS for AAD holds promise as a means to detect disease etiologies other than autoimmunity.
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| 8. |
- Brennan, S. J., et al.
(författare)
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Photometric and spectroscopic evolution of the interacting transient AT 2016jbu(Gaia16cfr)
- 2022
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Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 513:4, s. 5642-5665
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Tidskriftsartikel (refereegranskat)abstract
- We present the results from a high-cadence, multiwavelength observation campaign of AT 2016jbu (aka Gaia16cfr), an interacting transient. This data set complements the current literature by adding higher cadence as well as extended coverage of the light-curve evolution and late-time spectroscopic evolution. Photometric coverage reveals that AT 2016jbu underwent significant photometric variability followed by two luminous events, the latter of which reached an absolute magnitude of MV ∼ −18.5 mag. This is similar to the transient SN 2009ip whose nature is still debated. Spectra are dominated by narrow emission lines and show a blue continuum during the peak of the second event. AT 2016jbu shows signatures of a complex, non-homogeneous circumstellar material (CSM). We see slowly evolving asymmetric hydrogen line profiles, with velocities of 500 km s−1 seen in narrow emission features from a slow-moving CSM, and up to 10 000 km s−1 seen in broad absorption from some high-velocity material. Late-time spectra (∼+1 yr) show a lack of forbidden emission lines expected from a core-collapse supernova and are dominated by strong emission from H, He I, and Ca II. Strong asymmetric emission features, a bumpy light curve, and continually evolving spectra suggest an inhibit nebular phase. We compare the evolution of H α among SN 2009ip-like transients and find possible evidence for orientation angle effects. The light-curve evolution of AT 2016jbu suggests similar, but not identical, circumstellar environments to other SN 2009ip-like transients.
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| 9. |
- Eriksson, Daniel, et al.
(författare)
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GWAS for autoimmune Addison’s disease identifies multiple risk loci and highlights AIRE in disease susceptibility
- 2021
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Ingår i: Nature Communications. - : Nature Publishing Group. - 2041-1723. ; 12:1
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Tidskriftsartikel (refereegranskat)abstract
- Autoimmune Addison's disease (AAD) is characterized by the autoimmune destruction of the adrenal cortex. Low prevalence and complex inheritance have long hindered successful genetic studies. We here report the first genome-wide association study on AAD, which identifies nine independent risk loci (P < 5 × 10-8). In addition to loci implicated in lymphocyte function and development shared with other autoimmune diseases such as HLA, BACH2, PTPN22 and CTLA4, we associate two protein-coding alterations in Autoimmune Regulator (AIRE) with AAD. The strongest, p.R471C (rs74203920, OR = 3.4 (2.7-4.3), P = 9.0 × 10-25) introduces an additional cysteine residue in the zinc-finger motif of the second PHD domain of the AIRE protein. This unbiased elucidation of the genetic contribution to development of AAD points to the importance of central immunological tolerance, and explains 35-41% of heritability (h2).
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| 10. |
- Fretz, Samuel Joseph, 1987, et al.
(författare)
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Amine- and Amide-Functionalized Mesoporous Carbons: A Strategy for Improving Sulfur/Host Interactions in Li-S Batteries
- 2020
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Ingår i: Batteries and Supercaps. - : Wiley. - 2566-6223. ; 3:8, s. 757-765
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Tidskriftsartikel (refereegranskat)abstract
- Lithium-sulfur (Li-S) batteries are of great interest due to their potentially high energy density, but the low electronic conductivity of both the sulfur (S-8) cathode active material and the final discharge product lithium sulfide (Li2S) require the use of a conductive host. Usually made of relatively hydrophobic carbon, such hosts are typically ill-suited to retain polar discharge products such as the intermediate lithium polysulfides (LiPs) and the final Li2S. Herein, we propose a route to increase the sulfur utilization by functionalizing the surface of ordered mesoporous carbon CMK3 with polar groups. These derivatized CMK3 materials are made using a simple two-step procedure of bromomethylation and subsequent nucleophilic substitution with amine or amide nucleophiles. We demonstrate that, compared to the unfunctionalized control, these modified CMK3 surfaces have considerably larger binding energies with LiPs and Li2S, which are proposed to aid the electrochemical conversion between S-8 and Li2S by keeping the LiPs species in close proximity to the carbon surface during Li-S battery cycling. As a result, the functionalized cathodes exhibit significantly improved specific capacities relative to their unmodified precursor.
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