| 1. |
- Balasubramanian, T, et al.
(författare)
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Surface electronic band structure and (A)over-bar surface state lifetimes at the Be(10(1)over-bar-0) surface : Experiment and theory
- 2001
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Ingår i: Physical Review B. Condensed Matter and Materials Physics. - 1098-0121 .- 1550-235X. ; 64:20
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Tidskriftsartikel (refereegranskat)abstract
- The surface electronic band structure of the Be(10(1) over bar 0) surface is experimentally determined by angle-resolved photoemission and calculated by using density-functional theory. The experimental results agree well with the calculations, except for the fact that we were only able to resolve three surface states in the gap at (L) over bar, instead of four as predicted by the calculations. Through the temperature-dependent study, the phonon contribution subtracted width (h times inverse lifetime) of the shallow surface state at (A) over bar is found to be 51 +/- 8 meV. This is compared with the electron-electron interaction contribution to the width (53 meV) of the shallow surface state at A obtained from model potential calculations.
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| 2. |
- Barnett, NP, et al.
(författare)
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Identification and brief treatment of alcohol problems with medical patients : An international perspective
- 2003
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Ingår i: Alcoholism. - 0145-6008 .- 1530-0277. ; 27:2, s. 262-270
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Tidskriftsartikel (refereegranskat)abstract
- This article summarizes the proceedings of a symposium at the 2002 RSA meeting in San Francisco, California. The chair was Peter Monti and co-chair was Nancy Barnett. The aim of the symposium was to bring together researchers from the United States, Sweden, and Mexico to present current findings on the development and implementation of screening and intervention research in Emergency Departments (ED). Cheryl Cherpitel presented findings on the performance of the Rapid Alcohol Problems Screen (RAPS4), a 4-item instrument used for screening for alcohol dependence and harmful drinking in the ED. Dr. Cherpitel also presented for her collaborator, Guilherme Borges, their research on the performance of a number of screening measures including the RAPS among Mexicans and Mexican-Americans with alcohol-related disorders in the ED. Preben Bendtsen described the implementation of an alcohol screening and intervention procedure delivered by ordinary ED staff in Sweden. Nancy Barnett presented data on characteristics related to readiness to change alcohol use in a sample of young adults who were treated in an ED for injury or intoxication.
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| 3. |
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| 4. |
- Pavey, S, et al.
(författare)
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Microarray expression profiling in melanoma reveals a BRAF mutation signature
- 2004
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Ingår i: Oncogene. - : Springer Science and Business Media LLC. - 1476-5594 .- 0950-9232. ; 23:23, s. 4060-4067
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Tidskriftsartikel (refereegranskat)abstract
- We have used microarray gene expression pro. ling and machine learning to predict the presence of BRAF mutations in a panel of 61 melanoma cell lines. The BRAF gene was found to be mutated in 42 samples (69%) and intragenic mutations of the NRAS gene were detected in seven samples (11%). No cell line carried mutations of both genes. Using support vector machines, we have built a classifier that differentiates between melanoma cell lines based on BRAF mutation status. As few as 83 genes are able to discriminate between BRAF mutant and BRAF wild-type samples with clear separation observed using hierarchical clustering. Multidimensional scaling was used to visualize the relationship between a BRAF mutation signature and that of a generalized mitogen-activated protein kinase ( MAPK) activation ( either BRAF or NRAS mutation) in the context of the discriminating gene list. We observed that samples carrying NRAS mutations lie somewhere between those with or without BRAF mutations. These observations suggest that there are gene-specific mutation signals in addition to a common MAPK activation that result from the pleiotropic effects of either BRAF or NRAS on other signaling pathways, leading to measurably different transcriptional changes.
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| 5. |
- Persson, CM, et al.
(författare)
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Interfacial behavior of n-Octylß-D-glucopyranoside compared to that of a technical mixture consisting of octyl glucosides
- 2000
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Ingår i: Langmuir. - 0743-7463 .- 1520-5827. ; 16, s. 10227-10235
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Tidskriftsartikel (refereegranskat)abstract
- The difference in interfacial behavior between a technical mixture consisting of n-octyl glucopyranosides, having between 1 and 7 glucose units in the polar headgroup, and n-octylß-D-glucopyranoside was investigated using a range of methods. The forces acting between two hydrophobic solid surfaces across surfactant solutions were determined with a surface force apparatus. It was found that adsorption of the technical mixture generated a long-range repulsive force of electrostatic nature. At shorter separations a local minimum in the force curve (located on the repulsive side) was observed. Further in a steric repulsion dominated the interaction. In contrast, adsorption of pure n-octylß-D-glucopyranoside did not generate any long-range electrostatic double-layer force and an attractive force was present between the monolayer-coated surfaces close to contact. Wetting experiments showed that the technical mixture was a better wetting agent of hydrophobic surfaces (lower contact angle and higher wetting tension). The adsorption to air-liquid interfaces was also investigated by surface tension measurements and by measuring the forces acting across single foam films. The latter measurements were carried out using a thin film balance employing the porous frit technique. The technical mixture was more efficient in generating long-range electrostatic forces whereas the pure n-octylß-D-glucopyranoside was more efficient in generating stable Newton black films. Pyrene fluorescence measurements revealed that the micelles formed by the technical mixture continuously change its average composition with concentration toward structures with a more hydrophobic micellar core
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